Propecia's clinical study

[noorur]

http://www.docguide.com/news/content.ns ... 880078c249


On average, people have 1000 hairs per inch circle. In the propecia's clinical study, the particicants had 876 hairs per inch circle on aveage at baseline. So, the reason why those participants didn't regrow much hair was because they didn't lose too much hair in the first place.

To be honest, I personally think it would have been better if the participants had an average baseline of around 500-600 hairs per inch circle, so that way, they would have been able to make a better analysis of how good propecia was at regrowing hair.

I believe propecia can regrow alot more than 100 hairs per inch circle for those who have around 400-500 hairs per inch circle on average, and have been losing hair for the past 2-3 years.

 

[Bryan]

Where'd you get the idea that people have an average of 1,000 hairs per inch circle?

Bryan

 

[noorur]

wasn't it 1000 hairs per inch circle on average ?


i find it believable, because according to Propecia's clinical study, those with minor hairloss had 876 hairs on average at baseline.

do you have any other figures that the average haircount is different from 1000 hairs per inch circle on an average non-balding men ?

 

[Bryan]

wasn't it 1000 hairs per inch circle on average ?

Haven't you ever heard the general rule-of-thumb that there are about 100,000 hairs on a typical human head? If what you say above is true, then there would have to be about 100 circles' worth of hair on that typical head! Doesn't that seem like an awful lot of circles? Could you arrange 100 1-inch circles over your own head (taking into account the spaces between the circles)??

i find it believable, because according to Propecia's clinical study, those with minor hairloss had 876 hairs on average at baseline.

"Minor" hairloss? I dunno about that. The subjects in that trial were described in the study as: "Men 18 to 41 years of age, with mild to moderately severe vertex male pattern hair loss according to a modified Norwood/Hamilton classification scale (II vertex, III vertex, IV or V), were enrolled..."

do you have any other figures that the average haircount is different from 1000 hairs per inch circle on an average non-balding men ?

Yes. Here's what a noted authority (David A. Whiting, MD) says in "Male Pattern Hair Loss: Current Understanding" (International Journal of Dermatology 1998, 37, 566-571):

"The anatomy of bald or balding scalp shows changes which have been well documented. Regarless of age, balding scalps have a reduced density of terminal hair follicles when compared with non-bald people of the same age. Those aged 30-90 years with normal hair have been reported to have 459 follicles per square centimeter, compared with 306 in male pattern hair loss. Recent data suggest that follicular counts in normal adults average 326 per square centimeter, and, in those with Androgenetic Alopecia, 278 per square centimeter (5)...

(5) Whiting DA. Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male androgenetic alopecia. J Am Acad Dermatol 1993; 28: 755-763."

There are about 5.1 square centimeters in a 1-inch circle, so the average number of follicles quoted above for a normal, non-balding person would be about 326 x 5.1 = 1,662 follicles in a 1-inch circle. In other words, the average baseline haircounts in the Propecia trial (assuming a 1:1 hair:follicle correspondence, which is itself another can of worms) appear to be a little bit more than HALF of a normal, non-balding person. That seems reasonable to me.

Bryan

 

[noorur]

ok
thanks alot for your help dude

so, we will not be getting back nowhere near half the amount, if we currently have around 300-400 hairs per inch circle