Hi all
Just been looking at Dr Lee's website and have pulled out this extract re: DHT
"Although Finasteride may lower the serum level of DHT by 60-80%., the DHT reduction at the actual follicle is far less than 60%-80% because the predominant enzyme that converts testosterone to DHT in the scalp is type 1, 5-alpha reductase, which is not affected by finasteride.
On the other hand, the 5% concentration of azelaic acid in Xandrox will inhibit virtually all synthesis of DHT in the scalp where applied. It does this by inhibiting the synthesis of testosterone into DHT of both type 1 and type 2, 5-alpha reductase enzymes. The extra reduction of DHT via azelaic acid helps many patients grow hair who would not otherwise be able to do so. "
If type I is the main cause, would dutasteride be a better option?
Just been looking at Dr Lee's website and have pulled out this extract re: DHT
"Although Finasteride may lower the serum level of DHT by 60-80%., the DHT reduction at the actual follicle is far less than 60%-80% because the predominant enzyme that converts testosterone to DHT in the scalp is type 1, 5-alpha reductase, which is not affected by finasteride.
On the other hand, the 5% concentration of azelaic acid in Xandrox will inhibit virtually all synthesis of DHT in the scalp where applied. It does this by inhibiting the synthesis of testosterone into DHT of both type 1 and type 2, 5-alpha reductase enzymes. The extra reduction of DHT via azelaic acid helps many patients grow hair who would not otherwise be able to do so. "
If type I is the main cause, would dutasteride be a better option?