Ralf Paus company finds a new novel target for hair growth

FollicleGuardian

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Monasterium Laboratory Skin and Hair research, founded by the famous hair loss researcher Ralf Paus, filed a patent lately with a new interesting target for hair loss. Their new patent suggests that the hair follicle has taste receptors that regulate hair growth. This target receptor is called TAS2R4:

"Inverse agonist of the receptor such as Nα,Nα-bis(carboxymethyl)-l-lysine (BCML) results in hair growth promotion, delayed catagen promotion, increase in hair follicle proliferation and pigmentation, associated with upregulation of the expression of pro-anagenic growth factor IGF1 and downregulation of pro-catagenic growth factor TGFβ2" https://worldwide.espacenet.com/pat...7897/publication/EP3766545A1?q=pn=EP3766545A1

BCLM is an inhibitor of the hair follicle taste receptor. And is already available on the market.
 
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