Really Interesting Study On Male Pseudo Hermaphroditism And Their Hormonal Level !

michel sapin

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https://sci-hub.tw/https://doi.org/10.1016/0002-9343(77)90313-8.

really interesting point ; you can see the the picture on page 8 -9 .And the dudes are lean , even at 42 yo !
No gynecomastia at all .

You can see their hormonal level ;
*the DHT is in the low range / AND the testosterone level is really high !
read on page 11 ; the average test level was 989 ng/ ml ! this is crazy high .

That is a shame that they don't measure their oestradiol level , but it might be really low .

The guys got no acne / beard / body hair / lack of hair thinning . which is great .
But they seem to have a " small penis " , small height .
 

Armando Jose

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Also, that is a shame that they did not knew about the three isoenzimes of 5-reductases.
Probably the type one is operative in these persons, they have a good hair with a sebaceous gland working.
 

abcdefg

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Yeah try telling me there is no connection between facial hair/body hair and head hair. Women dont go bald, and dont have any facial hair like a man.
Yes, and this is exactly what propecia attempts to replicate which is why it works so well. Its just a shame it changes 5 ar 3 and maybe neurosteroids which was not part of the original intention for what this drug was supposed to do. Minus this it would be even safer.
 

abcdefg

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Also, that is a shame that they did not knew about the three isoenzimes of 5-reductases.
Probably the type one is operative in these persons, they have a good hair with a sebaceous gland working.

I dont think type 1 is that important in male pattern baldness merck did experiments and they had bad results using a type 1 inhibitor. Its mostly type 2, and I dont know enough about type 3 but maybe its involved? I dont know
 

michel sapin

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i think the reason it doesnr't worj that well for people with hairloss , is that the hairloss ' trigger is already pulled when they start propecia .
Because we can see here that a lack of DHT = juvenile hairline .
and teststerone level have nothing to do with hair loss ! their test level are like steroid users for some
 

michel sapin

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I really need to know their E2 level . Because , with such low DHT level and higher test , this is a recipe for gyno in normal people .
 

Armando Jose

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I dont think type 1 is that important in male pattern baldness merck did experiments and they had bad results using a type 1 inhibitor. Its mostly type 2, and I dont know enough about type 3 but maybe its involved? I dont know
Is it the study of merck?
Immunohistochemical localization of types 1 and 2 5alpha-reductase in human scalp
https://www.ncbi.nlm.nih.gov/pubmed/10583052

have you a link of merck's experiment with type 1 inhibitor?
TIA
 
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