Retin-A reduces Androgen Receptors?

[JWM]

A common belief among many is that retin-a reduces androgen sensors with continued use.

Is this just another forum rumor that has been spread for years or has there actually been studies done?

 

[Bryan]

I definitely read that in a study once, but don't ask me to cite it for you. It was a LOOONG time ago!

 

[JWM]

So it's true!!! :woot:

 

[JLL]

I'm sure I read that too just a while ago, but I can't find where.

 

[diffuse propecia]

9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor

although this is not retin-a, it still is a usefull find and is found in a topical formulation known as Panretin.

http://www.ncbi.nlm.nih.gov/pubmed/15650026