Jacob
Senior Member
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Male rats (Sprague-Dawley) were orally administered with TEOSIDETM
10 (5 mg) or finasteride (5 mg) and DHT (dihydrotestosterone) levels
in blood were measured before the treatment and 3, 6 and 8 hours
after the treatment. Quantitative evaluation of DHT in prostatic
tissue was carried out 6 hours after the treatment.*
At difference from finasteride, TEOSIDETM 10 effectively reduces
DHT blood levels starting from 3 hours after oral administration
with effects lasting up to 8 hours.
TEOSIDETM 10 lowers DHT levels in prostatic tissue with the
same efficacy of finasteride.
Also anti-inflammatory:
SYSTEMIC ANTI-INFLAMMATORY ACTIVITY
Experimental inflammation has been induced in CD1 mice by
intraperitoneal administration of lipopolysaccharide (LPS, 2,5 ?g/
animal). TEOSIDETM 10 (0,35 mg/Kg) has been orally administered
30 minutes before LPS injection and blood samples were collected
after 90 minutes for determination of the inflammatory markers
TNF-? and lipoperoxides. Teoside performance has been compared
with that of dexamethasone, injected intraperitoneally (30 mg/Kg).
(see pictures 3 and 4)
http://www.irbtech.com/fileadmin/user_upload/PDF_Prodotti/Brochure_Teoside10.pdf
http://www.irbtech.com/inglese/products/nutritional/htn-actives/teoside-10/