Yeah, just reading over the Testrogain information there:
Natural Dihydrotestosterone (DHT) Inhibitors:
As you know, the testes secrete several male sex hormones, which are collectively called androgens--testosterone, dihydrotestosterone, and androstenedione. When secreted, testosterone dwarfs the other two in concentration, so most people just refer to testosterone when discussing androgenic and anabolic effects of these hormones. Following secretion by the testes, most of the testosterone becomes loosely bound with either plasma albumin or a beta-globulin called gonadal steroid-binding globulin and circulates in the blood for about 20 minutes. By that time, it either adheres to tissues or becomes degraded into inactive products that are subsequently excreted. Much, if not most, of the testosterone that adheres to tissues is converted within the cells to dihydrotestosterone (a smaller amount goes to 5-alpha-androstanediol), commonly referred to as DHT. This is why we say that testosterone is converted to DHT at target tissues. Every target tissue, from the prostate to muscle cells, sees this conversion to some degree.
The rationale behind DHT inhibitors is that (a) if the conversion of testosterone to dihydrotestosterone is blocked, testosterone will remain in the bloodstream longer to positively affect and activate anabolic processes within muscle cells; and (b) since DHT is associated with some unwanted physiological effects, these can be minimized by blocking DHT. Research seems to be backing this rationale up.
Something I still don't understand is the True effects of DHT on the body. I believe them to be very complex. I'm still suffering severe side effects from taking (1mg) of Finasteride for 3 months. My Testicles have shrunk, my ejaculate is nearly non-existant, I've lost nearly all of my muscle mass and gained much weight, I'm very depressed. While I have all these problems, my hair loss has accelerated. What's going on? If these are side effects from low levels of DHT then why has my hair loss accelerated?
Who knows?