The TRUTH about % of finasteride side effects?

[Mew]

Compare what's listed below to their "2%" claim about Propecia side effects: http://www.propecia.com/finasteride/pro ... safety.jsp

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Check it out
http://www.merck.com/mmpe/lexicomp/finasteride.html


Adverse Reactions

Note: “Combination therapyâ€￾ refers to finasteride and doxazosin.

>10%:

Endocrine & metabolic: Impotence (19%; combination therapy 23%), libido decreased (10%; combination therapy 12%)

Genitourinary: Neuromuscular & skeletal: Weakness (5%; combination therapy 17%)

1% to 10%:

Cardiovascular: Postural hypotension (9%; combination therapy 18%), edema (1%, combination therapy 3%)

Central nervous system: Dizziness (7%; combination therapy 23%), somnolence (2%; combination therapy 3%)

Genitourinary: Ejaculation disturbances (7%; combination therapy 14%), decreased volume of ejaculate

Endocrine & metabolic: Gynecomastia (2%)

Respiratory: Dyspnea (1%; combination therapy 2%), rhinitis (1%; combination therapy 2%)

<1%, postmarketing and/or case reports: Hypersensitivity (pruritus, rash, urticaria, swelling of face/lips); breast tenderness, breast enlargement, breast cancer (males), prostate cancer (high grade), testicular pain

 

[Pondle]

The important thing is to compare to placebo (and test for statistically significant differences), rather than just looking at the raw numbers. Simply doing the latter is misleading. Comparing Propecia and Proscar trial groups directly is also misleading, because the latter were generally older, BPH being a problem usually confined to older men.

 

[Pondle]

wow 18.5% is far more than 2%.Anyways i think 18.5% is even way less then the real side effect rate is..Its 50/50

Rambo,

a. 18.5% refers to a sample of older guys, you're not drawing an appropriate comparison to the Propecia trial group, as I said
b. 12.2% of these older guys guys taking a sugar pill suffered from impotence 8)

 

[Pondle]

No one in there right mind would beleive 2% of people get sexual sides from propecia , That is pure and utter bullshit

Oh we've been though all this before! :doh: I don't think anyone is gonna change their minds either way.

 

[beaner]

No one in there right mind would beleive 2% of people get sexual sides from propecia , That is pure and utter bullshit

I believe it. I'll admit to being a little crazy, though.

 

[Mew]

In case anyone was wondering where the stats were from:

http://www.merckfrosst.ca/assets/en/pdf ... 2_06-E.pdf

Page 4.

 

[hairsucks]

I find it hard to belive the 2%,

Me and a person I know who started finasteride both stopped due to the sides. That's why I find it very hard to belive.

I can't imagine how many people use finasteride, so it is possibe both of us were in the 2% but I just don't think I belive it.

We both stuck with it for over 6 months to give the body time to adjust.

 

[e reed]

That makes me feel a little better about my side effect situation.