Topical probiotics to increase PGE2

drgs_not_hugs

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Stolen from longecity.org:


Given the positive effects on some skin and hair conditions, a proper topical probiotics formula might be a bonus for those wishing to manipulate prostaglandin production. Do homeless and non shampoo users benefit by not disturbing the scalp biome?


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188884/


"Increased levels of 6-ketoprostaglandin F1-α, epidermal growth factor (EGF) and b-fibroblast growth factor have been implicated in the protective effect displayed by peculiar bifidobacterial strains such asBifidobacterium brevis (B. brevis)and B. bifidum against gastric ulceration induced by acetic acid or ethanol in rats[55]. Pre-treatment of rats with Lactobacillus rhamnosus GG (L. GG) at 109 CFU/mL twice daily for three consecutive days was able to markedly lessen the suppressive actions of ethanol on mucus-secreting layer and trans-mucosal resistance along with an increase in the basal mucosal prostaglandin E2 (PGE2) levels and a concomitant reduction of cellular apoptosis[56].
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In a more recent study aimed at determining the role of viable lactobacilli in the healing of acetic acid-induced chronic gastric ulcer, Uchida et al[57] reported that a yogurt containing L. gasseri OLL 2716 inhibits the formation of HCl-induced acute gastric lesions through the generation of PGE2.
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