Minoxidil (MXD) is the most widely used drug in alopecia treatment, especially male-pattern hair loss. It is known to have a vasodilatory effect and expedite secretion of growth factors for hair regeneration.
Due to the characteristics of alopecia, it works effectively when applied to the topical skin area through transdermal delivery of MXD.
However, typical MXD delivery has the disadvantages of low efficiency of transdermal delivery and various side effects, such as tolerance, inflammation and low blood pressure.
Therefore, many studies have been investigated to improve the transdermal delivery efficiency of MXD applied to the skin and the therapeutic efficacy in alopecia, through the transdermal routes such as hair follicles, sweat glands or microneedle arrays.
biomaterialsres.biomedcentral.com
Due to the characteristics of alopecia, it works effectively when applied to the topical skin area through transdermal delivery of MXD.
However, typical MXD delivery has the disadvantages of low efficiency of transdermal delivery and various side effects, such as tolerance, inflammation and low blood pressure.
Therefore, many studies have been investigated to improve the transdermal delivery efficiency of MXD applied to the skin and the therapeutic efficacy in alopecia, through the transdermal routes such as hair follicles, sweat glands or microneedle arrays.
Transdermal delivery of Minoxidil using HA-PLGA nanoparticles for the treatment in alopecia - Biomaterials Research
Background Alopecia has become a very common disease that many people around the world are suffered. Minoxidil (MXD) is the most well-known commercialized drug in its treatment. However, in the case of MXD administration, there are some problems with low efficiency of transdermal delivery and...
biomaterialsres.biomedcentral.com