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Researchers from South Korea have now found effective ways to cure or at least help with male pattern baldness with three distinct natural treatments: pumpkin seed oil, cistanche tubulosa + laminaria japnica, and now rice bran extract. I had noticed this before with just two studies, but with the rice bran study being discussed today that makes three "scientific" studies published in the medical literature.
I don't know what's up with this bizarre sociological phenomenon, any ideas?
Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial
Jae-Suk Choi, Jae Beom Park, Woi-Sook Moon, Jin-Nam Moon, Sang Wook Son, Mi-Ryung Kim
Major in Food Biotechnology, Division of Bioindustry, College of Medical and Life Sciences, Silla University 2) Department of Dermatology, Korea University Ansan Hospital 3) Department of R&D, ECOMINE Co., Ltd.
https://www.jstage.jst.go.jp/article/bpb/38/12/38_b15-00387/_html#sec03.01
Efficacy of Cistanche Tubulosa and Laminaria Japonica Extracts (MK-R7) Supplement in Preventing Patterned Hair Loss and Promoting Scalp Health
Joon Seok, Tae Su Kim, Hyun Jung Kwon, Sung Pyo Lee, Myung Hwa Kang, Beom Joon Kim,and Myeung Nam Kim
Department of Dermatology, Chung-Ang University College of Medicine, Seoul 156-755, Korea.
Misuba RTech Co., Ltd., Asan 336-795, Korea.
Department of Food and Nutrition, Hoseo University, Asan 336-795, Korea.
http://synapse.koreamed.org/search....7762/cnr.2015.4.2.124&code=0214CNR&vmode=FULL
Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
Young Hye Cho, Sang Yeoup Lee, Dong Wook Jeong, Eun Jung Choi, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, and Hyeong Soo Cha
Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Beomeo-ri, Mulgeum-eup, Yangsan 770-626, Gyeongsangnam-do, Republic of Korea
Medical Education Unit, Pusan National University School of Medicine, Yangsan 626-870, Republic of Korea
Department of Family Medicine, Pusan National University Hospital, Busan 602-739, Republic of Korea
Centum Family Clinic, Busan 612-020, Republic of Korea
http://www.hindawi.com/journals/ecam/2014/549721/abs/
Edited to add on April 7th, 2015
Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression.
Park S1, Erdogan S, Hwang D, Hwang S, Han EH, Lim YH.
Department of Integrated Biomedical and Life Sciences, Graduate School, Korea University.
Alopecia is an important issue that can occur in people of all ages. Recent studies show that bee venom can be used to treat certain diseases including rheumatoid arthritis, neuralgia, and multiple sclerosis. In this study, we investigated the preventive effect of bee venom on alopecia, which was measured by applying bee venom (0.001, 0.005, and 0.01%) or minoxidil (2%) as a positive control to the dorsal skin of female C57BL/6 mice for 19 days. Growth factors responsible for hair growth were analyzed by quantitative real-time PCR and western blot analysis using mice skins and human dermal papilla cells (hDPCs). Bee venom promoted hair growth and inhibited transition from the anagen to catagen phase. In both anagen phase mice and dexamethasone-induced catagen phase mice, hair growth was increased dose dependently compared with controls. Bee venom inhibited the expression of SRD5A2, which encodes a type II 5α-reductase that plays a major role in the conversion of testosterone into dihydrotestosterone. Moreover, bee venom stimulated proliferation of hDPCs and several growth factors (IGF-1R, VEGF, FGF2, and FGF7) in bee venom-treated hDPCs dose dependently compared with the control group. In conclusion, bee venom is a potentially potent 5α-reductase inhibitor and hair growth promoter.
http://www.ncbi.nlm.nih.gov/pubmed/27040904
I don't know what's up with this bizarre sociological phenomenon, any ideas?
Safety and Efficacy of Rice Bran Supercritical CO2 Extract for Hair Growth in Androgenic Alopecia: A 16-Week Double-Blind Randomized Controlled Trial
Jae-Suk Choi, Jae Beom Park, Woi-Sook Moon, Jin-Nam Moon, Sang Wook Son, Mi-Ryung Kim
Major in Food Biotechnology, Division of Bioindustry, College of Medical and Life Sciences, Silla University 2) Department of Dermatology, Korea University Ansan Hospital 3) Department of R&D, ECOMINE Co., Ltd.
https://www.jstage.jst.go.jp/article/bpb/38/12/38_b15-00387/_html#sec03.01
Efficacy of Cistanche Tubulosa and Laminaria Japonica Extracts (MK-R7) Supplement in Preventing Patterned Hair Loss and Promoting Scalp Health
Joon Seok, Tae Su Kim, Hyun Jung Kwon, Sung Pyo Lee, Myung Hwa Kang, Beom Joon Kim,and Myeung Nam Kim
Department of Dermatology, Chung-Ang University College of Medicine, Seoul 156-755, Korea.
Misuba RTech Co., Ltd., Asan 336-795, Korea.
Department of Food and Nutrition, Hoseo University, Asan 336-795, Korea.
http://synapse.koreamed.org/search....7762/cnr.2015.4.2.124&code=0214CNR&vmode=FULL
Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial
Young Hye Cho, Sang Yeoup Lee, Dong Wook Jeong, Eun Jung Choi, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, and Hyeong Soo Cha
Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Beomeo-ri, Mulgeum-eup, Yangsan 770-626, Gyeongsangnam-do, Republic of Korea
Medical Education Unit, Pusan National University School of Medicine, Yangsan 626-870, Republic of Korea
Department of Family Medicine, Pusan National University Hospital, Busan 602-739, Republic of Korea
Centum Family Clinic, Busan 612-020, Republic of Korea
http://www.hindawi.com/journals/ecam/2014/549721/abs/
Edited to add on April 7th, 2015
Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression.
Park S1, Erdogan S, Hwang D, Hwang S, Han EH, Lim YH.
Department of Integrated Biomedical and Life Sciences, Graduate School, Korea University.
Alopecia is an important issue that can occur in people of all ages. Recent studies show that bee venom can be used to treat certain diseases including rheumatoid arthritis, neuralgia, and multiple sclerosis. In this study, we investigated the preventive effect of bee venom on alopecia, which was measured by applying bee venom (0.001, 0.005, and 0.01%) or minoxidil (2%) as a positive control to the dorsal skin of female C57BL/6 mice for 19 days. Growth factors responsible for hair growth were analyzed by quantitative real-time PCR and western blot analysis using mice skins and human dermal papilla cells (hDPCs). Bee venom promoted hair growth and inhibited transition from the anagen to catagen phase. In both anagen phase mice and dexamethasone-induced catagen phase mice, hair growth was increased dose dependently compared with controls. Bee venom inhibited the expression of SRD5A2, which encodes a type II 5α-reductase that plays a major role in the conversion of testosterone into dihydrotestosterone. Moreover, bee venom stimulated proliferation of hDPCs and several growth factors (IGF-1R, VEGF, FGF2, and FGF7) in bee venom-treated hDPCs dose dependently compared with the control group. In conclusion, bee venom is a potentially potent 5α-reductase inhibitor and hair growth promoter.
http://www.ncbi.nlm.nih.gov/pubmed/27040904