Using finasteride and dutasteride together? finasteride/dutasteride effectiveness?

Which applies to you?

  • Dutasteride worked better than Finasteride.

    Votes: 0 0.0%

  • Total voters
    12

paximperia

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I've been taking 1mg Finasteride for about 5 months now and have been thrilled with the results. It took about 2 months of very light shedding, then the shedding stopped and my hair completely stopped falling out. I experienced a decent amount of regrowth. I only see maybe two or three hairs per day in the sink. The hair growth has pretty much stopped now, and I think this is about as good as it will get with Propecia. My dad and uncle went completely bald by the time they were 30, so I'm afraid that Propecia will stop working sooner or later.

Since earlier is better, I'm considering starting Dutasteride before it continues. I have two concerns, the first being that it is still basically an experimental treatment for hair loss. I remember reading about some of the earlier experimental DHT inhibitors (prior to Proscar) that never made it to market. They reduce DHT serum, but are ineffective at treating BPH (and possibly hair loss?), which makes me think that they still don't have a good grasp on how it all works. There are also no long-term studies (2+ years) on hair loss and Avodart, as far as I know.

If I start taking it and my hair starts falling out, I won't know if it's ineffective or if I'm going through a shedding period. I would hate to lose what I've gained/saved from Propecia.

Is there anyone here who is taking both Propecia and Avodart together? I understand that this might not be the best idea, but at least I'll be able to tell if Avodart works without risking losing the hair I currently have. Once the Avodart has had time to be effective (6-9 months or so), I can stop the Propecia and see if I lose hair. If anyone is doing this, any side effects? I understand that this is a somewhat risky prospect, and there are no studies on safety reguarding combinations, but I know I'm going to lose it all if I'm not careful.

Are there any Propecia responders here that responded even better to Avodart? Any people that responded worse?
 

Pondle

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It's pointless to take Avodart if you're responding well to Propecia and you're still only at the 5 month mark. Maximum effect is only seen within 12 months, and average hair counts (pulled down by the 17% or so who are non-responders or poor responders) begin to decline after yr 2. You could still be above baseline on Propecia more than 5 yrs after starting treatment.

Avodart is undoubtedly superior to Propecia, but only modestly so. Avodart's advantage is its superior inhibition of Type II 5AR (selectively targeted by Propecia) and effectiveness against Type I 5AR (which Propecia does not block, but is less important in hair loss anyway). Dutasteride inhibits 98.5% of DHT from 5ar2 and 50% from 5ar1 at 0.5mg/day. finasteride inhibits 90% and 0% respectively at 5mg/day, slightly less at 1mg/day.
 

dem

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I took finasteride for 9 years before I seemed to no longer respond to it. finasteride helped maintain my hair and provide some new hair. I learned about dutasteride and switched. Fortunately, I responded well to it and have experienced thicker hair both in the temples and vertex. However, the sheds I experienced on dutasteride are more severe and prolonged. Nevertheless, I feel better about my hair on dutasteride.
 
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Timi

Guest
dutasteride

dem

your better Hair can also be from minoxidil (Foam)
Aug 2006 minoxidil
Jun 2006 dutasteride



Timi
 

dem

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thats also true timi. However, i think that dutasteride had much more of an impact than finasteride.
 
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Timi

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dutasteride

dem

have you No Problem with Bodyfat?

under dutasteride i am fatter and fatter
face and Neck bigger
Thigh and ***-Belly fat
Eye rings -glassy eyes
and light Gyno

come this from higher Östrogen??

I think dutasteride is to heavy for me
0,5mg all 3Days and have this side Effect



Timi
 

paximperia

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Body fat isn't listed as one of the side-effects. It seems unlikely.

"Side effects may include:
Breast tenderness, decreased sex drive, ejaculation problems, enlarged breasts in males, hives, impotence, itchy spots, rash"

By the way, enlarged breasts was only 1.6% higher than placebo in people taking 0.5mg/day.
 

dem

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Re: dutasteride

Timi said:
dem

have you No Problem with Bodyfat?

under dutasteride i am fatter and fatter
face and Neck bigger
Thigh and ***-Belly fat
Eye rings -glassy eyes
and light Gyno

come this from higher Östrogen??

I think dutasteride is to heavy for me
0,5mg all 3Days and have this side Effect

Timi

Timi,
I have no problems with body fat or any of the other listed sides. I originally did feel a decrease in my libido, however, that only lasted about a month.

The sides should dissipate after some time. If they don't, I really don't know what to say other than maybe you should revert back to finasteride.

Are you taking anything else that could help contribute to the side effects?
 

Nick4441

Experienced Member
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My advice - Don't mess with something that is working.

Although dutasteride is stronger there are obviously chemical differences between the two because some people respond better on finasteride than dutasteride. I never responded to finasteride and I moved to dutasteride cos finasteride did not work for me..too early for results yet but I have no sides on dutasteride and I had heavy sides on Propecia so something is different between these two drugs other than the simple 'it blocks more DHT'.

So only change if finasteride stops working...excellent news that it is working for you, stick with it.
 
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Timi

Guest
dutasteride

dem

I had take 2Days Proscar one Day 0,5Dut

i have with Proscar sides- Eyes burning-Tiredness

Proscar my Problem? and not dutasteride???
the last time i have take 2x1,25 Proscar Dayli
and Bodyfat without dutasteride in former times
Bodyfat was always a Problem from DHT Pills (Proscar)

in ouer Board says many People under Proscar fat
and under dutasteride not



Timi
 

person

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Timmah!!! Timiarr! Timah!!!!
 
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