waynakyo
Experienced Member
- Reaction score
- 465
Dr Wesley has been posting updates on BTT regarding pilofocus. A lot of people are comparing his weak statement of possibility of regeneration (he made no claims) with that of Cooley while I agree with him they are different. He is not implanting plucked hairs and he is able to cleanly (from below the scalp) transect a follicle. Yet he never mentioned the study (or others) showing that transected follicles grow.
For some reason I was never able to register at BTT, anyone (hellhouser?) can relay my question to him, which is basically to ask him his opinion on the study below which shows that transected follicles grow back and if that is what he has in mind....
http://www.hairsite.com/hair-loss/im...879_file43.pdf
BACKGROUND The use of bisected hair follicles in hair transplantation has been previously reported,but the capacity of each half to regenerate the entire hair has not been clarified.
OBJECTIVE To evaluate duplicative surgery rate of success and to analyze the cell populations involvedin hair regeneration.
METHODS We screened 28 patients undergoing duplicative surgery. Approximately 100 hair folliclesfrom each patient were horizontally bisected and implanted. Upper and lower portions were stained forthe known epithelial stem cell markers CD200, p63,b1-integrin, CD34, and K19.
RESULTS Similar percentages of hair regrowth after 12 months were observed when implanting theupper (72.770.4%) and lower (69.271.1%) portions. Expression of CD200, p63, and b1-integrin wasdetected in both portions, whereas K19 and CD34 stained different cell populations in the upper andlower fragment, respectively.
CONCLUSION Duplicative surgery might represent a successful alternative for hair transplantation,because both portions are capable of regenerating a healthy hair. Moreover, our results suggest thepossible presence of stem cells in both halves of the follicle.
For some reason I was never able to register at BTT, anyone (hellhouser?) can relay my question to him, which is basically to ask him his opinion on the study below which shows that transected follicles grow back and if that is what he has in mind....
http://www.hairsite.com/hair-loss/im...879_file43.pdf
BACKGROUND The use of bisected hair follicles in hair transplantation has been previously reported,but the capacity of each half to regenerate the entire hair has not been clarified.
OBJECTIVE To evaluate duplicative surgery rate of success and to analyze the cell populations involvedin hair regeneration.
METHODS We screened 28 patients undergoing duplicative surgery. Approximately 100 hair folliclesfrom each patient were horizontally bisected and implanted. Upper and lower portions were stained forthe known epithelial stem cell markers CD200, p63,b1-integrin, CD34, and K19.
RESULTS Similar percentages of hair regrowth after 12 months were observed when implanting theupper (72.770.4%) and lower (69.271.1%) portions. Expression of CD200, p63, and b1-integrin wasdetected in both portions, whereas K19 and CD34 stained different cell populations in the upper andlower fragment, respectively.
CONCLUSION Duplicative surgery might represent a successful alternative for hair transplantation,because both portions are capable of regenerating a healthy hair. Moreover, our results suggest thepossible presence of stem cells in both halves of the follicle.