Why I do not have side effects yet from 0,5mg Dutasteride?

[BoyBoi]

Normally when Im take 0,25mg Finasteride I always feel tired and a little bit exhausted for 1-2 days.

Yesterday at night it was the first time Im took 0,5 mg Dutasteride - its like Im took nothing. Im feel much better with it than with a little dose of Finasteride.

Is here somebody who have the same experience with Dutasteride? Im asking because Im bought it online and it comes from an pharmacy in Portugal, just want to be sure its not an fake.

 

[Catagen]

At 0.5mg daily it takes a full month until it reaches steady state serum levels and starts working properly. Finasteride starts working immediately.

 

[corkmeister]

At 0.5mg daily it takes a full month until it reaches steady state serum levels and starts working properly. Finasteride starts working immediately.

What?

 

[BoyBoi]

Yes it can happen. I myself I'm usually like that.

What about your hair though?

Since Im on Dutasteride, the scalp itching is gone and the pimple on my head too, my face looks clean, no pimples anymore...
so it should work, its just weird for me to have less side effects than with finasteride

 

[BoyBoi]

At 0.5mg daily it takes a full month until it reaches steady state serum levels and starts working properly. Finasteride starts working immediately.

really?? when Im looking on graphs it looks more like Dutasteride should work immediately too?

 

[BetaBoy]

The vast majority don't experience sides

 

[Catagen]

really?? when Im looking on graphs it looks more like Dutasteride should work immediately too?

You dont get the desired 90% serum suppression immediately, which graphs are you lookin at?

 

[BoyBoi]

For me its feels like that the Dutasteride works, so should not be a fake product Im think.
Im just wondering why Im feel mentally much more clearer than with Finasteride.

 

[Seuxin]

Because a LOT of people get sides from finasteride and no sides with dutasteride. It's real. So continue and just see what happens. It's my case. dutasteride every day since 2016. No sides. All is fine

 

[LouisSarkozy]

Because a LOT of people get sides from finasteride and no sides with dutasteride. It's real. So continue and just see what happens. It's my case. dutasteride every day since 2016. No sides. All is fine

you're taking 0.5 mg of dutasteride daily right? thanks

 

[Seuxin]

you're taking 0.5 mg of dutasteride daily right? thanks

No, i made a mistake..i take one day ON, one OFF. So a 30 caps box last me 60 days .

 

[supermusic]

How can you notice these effects in just one day? the effects of finasteride are usually cumulative. Rather it seems nocebo

 

[BoyBoi]

Im a sensitive person, I can notice that very quickly.

But everything is okay, Dutasteride works very well! No itching on the scalp and my hair looks healthier already. The libido is lower, but not too low, its okay and Im dont feel like crap like when Im was on Finasteride

 

[Feelsbadman.jpg]

Similar experience. Was on finasteride for 4 years, never really noticed significant sides, but switched to dutasteride for last two and its a big difference. Much clearer thinking and better libido. I think finasteride is harder on the body as it is a progesterone analogue while dutasteride is a testosterone analogue.

 

[Grim]

I doubt you had fake dutasteride, the stuff is dirt cheap to produce. There is a chance your body adapted to the reduced dht around the same time you took dutasteride.

 

[Grim]

It could also be the formulation of the drugs

 

[Grim]

As in?

I've tried 3 different Dutasteride brands and although on papers everybody would say that it's all the same the reality is that the 3 of them had different effects on me. So I believe that necessarily there must be some type of difference for this to happen.

Im not too sure, I hope to learn more on drug formulations once I finish premed and get to damn med school. I've noticed with regular over the counter things such as sleep pills for example, I've had certain brands give me terrible dry mouth but others do not. I also tried a different brand of adderall once, it made me feel so off. Im starting to believe the formulation or whatever little things they throw in may cause certain side effects. Same thing with my vitamins I take. One brand of multivitamin i take makes me want to vomit. But the others do not.

 

[Grim]

Could these extra components alter the effectivness of the main compound (dutasteride)?

I don't think they alter the effectiveness, at least to any noticeable level. I believe its the vehicle these medications use. I've noticed i never have side effects if the medication comes in a gel capsule form. But tablets, at least for me have a higher side effect profile.

 

[Grim]

Could these extra components alter the effectivness of the main compound (dutasteride)?

I also believe these foreign drugs are made with the cheapest possible binding component. So side effects are probably more common with these foreign pills. The original dutasteride I took was cheap as hell and the prescription ones I take now are much better quality.

 

[dehoha]

There are plenty of people who report less side effects from dutasteride than finasteride. Generally speaking, finasteride causes less sides including ED, gyno, testicular pain, depression, fatigue, etc, but it's not the same for everybody. It is true that it takes 3-4 months for dutasteride to reach steady state level of serum DHT. This is directly from FDA. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021319s015lbl.pdf