In this study, we examined the mechanism of hair regression induced by endothelins in in vivo and in vitro study. Histological examination revealed that the catagen-like morphological change of anagen…
In this investigation we have designed to find out whether Dermal Papilla cells secrete growth factors like IGF-1, and the effect of androgens on their expression of the above growth…
The objective of the study was to determine whether age affects the concentration of free amino acids in hair roots in men from the UK..
In order to investigate how the expression of epidermal proteins associated with differentiation also occurs in hair follicles according to its cycle, we performed immunohistochemistry and…
Neurotrophins have several non-neuronal functions in the skin. Previously we have shown that p75 kD neurotrophin receptor plays an important role during HF morphogenesis and that neurotrophins…
One of the most accepted means to identify keratinocyte stem cells takes advantage of the fact that they are normally rarely cycling in vivo, and can be detected experimentally as the…
Epithelial-mesenchymal interactions govern the initiation of organ development, subsequent morphogenesis and terminal cytodifferentiation. The developing tooth of the mouse is a good model for…
It is well known that sex hormones such as androgen and estrogen influence the hair growth in several animals. Aromatase is a member of cytochrome P-450 gene superfamily and…
Nitric oxide (NO) has been identified as an important mediator in various physiological and pathophysiological processes of the skin, such as regulation of blood flow, melanogenesis…
Although potassium channel openers such as minoxidil promote hair growth in vivo, the mechanisms by which they do so are unclear. Using a red deer whole hair follicle culture system we…