Although potassium channel openers such as minoxidil promote hair growth in vivo, the mechanisms by which they do so are unclear. Using a red deer whole hair follicle culture system we…
Signal transducer and activator of transcription 3 (Stat3) is involved in many signaling pathways for growth factors and cytokines. Its deficiency in mice therefore…
While the significance of androgens as major modulators of hair growth is well-established, much less is known on the exact follicular functions of other nuclear hormone receptor…
The last decade has witnessed an explosion of information regarding the manner in which steroid hormones modulate gene expression. At present, a body of increasingly…
Partial sequencing of randomly selected clones from cDNA libraries of specific tissues or cell types to generate expressed sequence tags (ESTs) has proven to be a rapid…
The use of minoxidil topical solution (MTS) for the treatment of androgenetic alopecia (AGA) in patients less than 18 years of age has not been previously characterized. The objective of this study was to…
A post-marketing surveillance study in over 11,000 minoxidil topical solution (MTS) 2% users with androgenetic alopecia demonstrated that 4 out of 5 subjects experienced a slowing or stopping of hair loss with…
There are no pharmacokinetic data on minoxidil topical solution (MTS) in adolescents with androgenetic alopecia (AGA). The objective of this investigation was to establish the…
Finasteride is an effective oral medication in the treatment of androgenetic alopecia (AGA). Minoxidil has a direct effect on hair growth by stimulating dermal papillae or follicular…
Capsaicin induces the release of substance P(SP) which is believed to play an important role in murine hair growth and cycle. Minoxidil, the only approved topical hair…
