The last decade has witnessed an explosion of information regarding the manner in which steroid hormones modulate gene expression. At present, a body of increasingly…
Partial sequencing of randomly selected clones from cDNA libraries of specific tissues or cell types to generate expressed sequence tags (ESTs) has proven to be a rapid…
A novel gene therapy technology of hair follicles has been developed which results for the first time in efficient genetic and phenotype alteration of the hair shaft. Mouse anagen skin fragments in histoculture…
Senescent thinning of the scalp hair, or thinning that occurs after age 60, is poorly understood, and it is unclear whether this is a distinct entity or part of the continuum of androgenetic alopecia (AGA).
Histologic analysis of horizontal sections of scalp biopsies in men and women with androgenetic alopecia is an established method of measuring progression of hair loss or hair regrowth. Detailed…
ndrogenetic alopecia (AGA) is an autosomal dominant condition with variable penetrance that affects about 50% of men and women. Androgenetic Alopecia is androgen mediated with puberty…
In male androgenetic alopecia (AGA), global changes of scalp hair observed on many years are the result of discrete structural and/or functional modifications at the level of individual hair follicles…
The use of minoxidil topical solution (MTS) for the treatment of androgenetic alopecia (AGA) in patients less than 18 years of age has not been previously characterized. The objective of this study was to…
A post-marketing surveillance study in over 11,000 minoxidil topical solution (MTS) 2% users with androgenetic alopecia demonstrated that 4 out of 5 subjects experienced a slowing or stopping of hair loss with…
There are no pharmacokinetic data on minoxidil topical solution (MTS) in adolescents with androgenetic alopecia (AGA). The objective of this investigation was to establish the…
