Is this a possible hope, or another bull**** ?

[rjmogka]

I just found this:

http://www.dailymail.co.uk/news/arti...ket-years.html

This is from today, seems like the PGD2 thing finnaly kicks the system
and people are starting to get feared about someone else will find the solution or the "almost solution" before them.

Cotsarelis is scared as **** that histogen will be the next thing, or Neogenic or whatever.
This is an inside war between those companies, and to me it seems like until 2014 we will have maybe not the solution,
but a very better treatment.

It looks like more than a try of getting readers, but, who knows...
Im just another 21 years old who grabs any hope he can catch.

 

[baldnesssadness]

nice post!!! this is really important , i was wondering what they did with this research and im glad they took it a step further.. this has to be it, what we all been waiting for, just 2 down sides to this , first didnt they get further with the research? they say exact the same thing they said in march when this was found, only news is that this is gonna be a new treatment about 2 years. Did blocking pgd2 work? were are the results? and lastly this not the first time cotsarelis promises something will come out about 2-5 years... so in short.. its not bull**** this is possible...but dont get to exited as the others say... i cant wait till others know about this.

- - - Updated - - -

Dr Cotsarelis said: ‘We think these findings will have implications beyond male pattern baldness but, even if they don’t, we think it will be exciting.
what the heck does he mean by this?

btw guys lets have a cermony where we try to summon the great forum posters boldy and squeegee, we really need those guys now.

 

[Sparky4444]

...well, I have been musing this over the last few months that it comes down to keeping what you have because something will be coming shortly that will absolutely stop hairloss...but regrowth will be the tough one -- or at least regrowth that would give enough comfort as opposed to peach fuzz or short vellus hairs that never go any further than 1cm in length...

...but it seems to me that whatever happens with this, it will be better for us with Histogen coming and the drug guy's fighting over a solution. Somehow I think we will need both method's to get back acceptable coverage back... This may even push Histogen's target market date sooner...

 

[2020]

what the article doesn't mention is that ALL THREE prostaglandins are out of balance... PGD2 is elevated yes so it must come down, HOWEVER PGE2 is too low and PGF2 is too high! What are you going to do about those other two? Blocking PGD2 would only address a third of the problems

PGD2 is not the main problem, it's a marker of something bigger - my guess is inflammation.

 

[Sparky4444]

...but the issue with PGD2 is that it's levels are localized....no where did anybody ever say that PGD2 levels are high systemically...or did they??? It seems to me that something is going on biochemically specific to the hair follicle that is binding PGD2 and causing inflammation...

I agree, there is more to this story, but much like a rat leaving a **** dropping trail, observing the high localized levels of PGD2 in the scalp should expose a new trail to follow...

 

[odalbak]

"Amexidil, which increase blood flow to the hair follicles could in fact accelerate hair loss."

Where did they find that minoxidil 5% "could in fact accelerate hair loss" ?

 

[lobsterlobster]

I don't think anyone can promise us anything, but this gives us early thinners more reason to hope int:int:int:int:

 

[tedlin01]

Great news! We already have safe CRTH2 Antagonists(Prostaglandin D2 Receptors) on the market so it shouldnt take long to try them on in terms of male pattern baldness.

I just wonder where he presented this.. I would love to see the source of a quote from him..

 

[Vox]

...but regrowth will be the tough one -- or at least regrowth that would give enough comfort as opposed to peach fuzz or short vellus hairs that never go any further than 1cm in length...

Definitely. But personally I would be OK with a full coverage by vellus hair of 1 cm or so, because I buzz down what remains on my head to about 0.5 cm every one or two weeks.

 

[somone uk]

maybe you can believe this, but you're then obliged to believe it'll give you cancer alongside being tall, being short, going outside, being a recluse, mobile phones and being bald

 

[LawOfThelema]

lol, good. researchers and proprietors being scared of each others product is beneficial for you as a balding individual... everyone will ratchet their own work up and get them to pump new and better product out to compete with one another

i'm so glad that im starting to bald now in the 2010s rather than the 70s when my dad started to bald

 

[baldnesssadness]

are you sceptical or sarcastic? somone uk

 

[Jamesallenliwei]

That's really a good news!!!
I hope one day there is nobody in the world with any hair problem!!!

 

[Sparky4444]

lol, good. researchers and proprietors being scared of each others product is beneficial for you as a balding individual... everyone will ratchet their own work up and get them to pump new and better product out to compete with one another

i'm so glad that im starting to bald now in the 2010s rather than the 70s when my dad started to bald

Yeah, it's funny though -- we're such a media-driven, shallow, image based society now....way more so than in the 70's...I think balding in the 60's and 70's wasn't such a big deal for women...I think it is a bigger deal now for women -- more so than they admit to

 

[abcdefg]

I will just say I personally want hair for myself it really does not have anything to do with girls or for other people but how I feel about myself. That being said I know for a fact many men want hair solely to get better girls. I would just say higher population means more competition for the small percent of girls considered by many to be hot so if say male pattern baldness is not a good thing then your in some trouble considering how many other men want those same girls. So maybe its not shallow it just comes with population growth and well the media plays a large role but that is another story for a different day.

 

[Aks20]

Hair loss is a confidence sapping disease, especially if it strikes you in the crucial young years of your life.

I think Cotsarelis product has a good chance of addressing the issue as it has logic and science behind it, that he is pushing ahead with his means that he has actual invitro tests at the very least showing that it works. Perhaps even actual clinical trials conducted with minimal fuss and publicity, although not as comprehensive as those required for FDA clearance.

 

[somone uk]

are you sceptical or sarcastic? somone uk

both, 2 year timescale is first hurdle of bullshǐt, second is the notion that PGD2 inhibitors necessarily prevent baldness (even if PGD2 is the cause we have no where near sufficient evidence that the inhibitors will make a difference) and finally the daily mail is barely a decent source for science, these are the people who propagate hate through stereotypes and million and 1 cancer scares

 

[baldnesssadness]

both, 2 year timescale is first hurdle of bullshǐt, second is the notion that PGD2 inhibitors necessarily prevent baldness (even if PGD2 is the cause we have no where near sufficient evidence that the inhibitors will make a difference) and finally the daily mail is barely a decent source for science, these are the people who propagate hate through stereotypes and million and 1 cancer scares

the reason its only 2 years, is because a anti pgd2 has allready been tested before... you see correct me if im wrong but pgd2 is responsible for asthma on the lungs or something.. and they were ready with the phase 2... and ur correct about the second thing we havent seen suifficient evidence yet.. yes pgd2 is 3x times more on the balding scalp but its been like 6 months since they have found this.. have they blocked pgd2 in the scalp? no... so we cant be for sure... its the main cause but pgd2 thing seems logical... i just dont understand why cotsarelis didnt research more on this... he goes right to make medicines... and yes this wasnt in medical news or other medicine sight... show us some results cotsarelis so we can feel secure about this!!!

 

[Sparky4444]

...listen...this Dr. Costeralis knows something we don't...otherwise he wouldn't be putting his *** on the line...also, I bet you dime's to dollars he already did some informal testing and is already seeing results...

...c'mon people -- wake up.... if you're a doctor you don't put yourself out on a limb---it's professional suicide...especially when it comes something as touchy as hairloss!

 

[abcdefg]

If he has no evidence this works in people then he really has nothing more then a theory. He must know there is a big difference between mice and humans plenty of things work on mice but do not work as well for us.