Is There Any Hope For Future Hair Loss Treatments?

[Roberto_72]

Some of us already do that. I've spent thousands already.

Anyone who doubts we will have better treatments 20 years from now is the ultimate pessimist. Stem cell and genetic breakthroughs are happening at a rapid pace. Barring some sort of global catastrophe that halts medical progress, we will have a cure by 2040, no doubt.

Mate, this is exactly what we said 20 years ago... genetic modification is something people have been talking about for a LONG time...

So, I don't know about "ultimate pessimism..." I hope you're right, but maybe doubt is more based on past experience than pessimistic.

I'd be VERY happy if hair replication in vitro was available in ten years from now. More than that, who knows?

 

[Afro_Vacancy]

Mate, this is exactly what we said 20 years ago... genetic modification is something people have been talking about for a LONG time...

So, I don't know about "ultimate pessimism..." I hope you're right, but maybe doubt is more based on past experience than pessimistic.

I'd be VERY happy if hair replication in vitro was available in ten years from now. More than that, who knows?

Wouldn't that constitute a cure?

 

[Torin]

If a cure really is 40 years away the current researchers are toying with our hopes with their 5 and 10 years predictions.

 

[Roberto_72]

Wouldn't that constitute a cure?

exactly, David. That is all I am waiting for.
At the same time, I imagine it is not what everybody is waiting for. I already had two transplants so there is no reason for not doing a MASSIVE third. Yet I understand not everyone would want to have a hair transplant if they are not NW3+

 

[Roberto_72]

If a cure really is 40 years away the current researchers are toying with our hopes with their 5 and 10 years predictions.

If you read the posts of 2005 of this very forum, the time span is the same: 5 or 10 years were considered a sufficient period for some kind of revolution.
I don't know why the human mind associated five and ten years with a LOOONG time. It is interesting that that is the period (more or less) of extension of the two most recent World Wars.

 

[lickawrist]

if male pattern baldness wasnt so damn polygenic, we could just find that one "hair loss" gene and abolish baldness rather than ponder about complex procedures to "treat" (not cure) baldness...but no...nature has to be so damn complicated.

 

[abcdefg]

I still think all future stuff that comes out is basically going to stack onto existing stuff. So if 3 new things came out say SM, seti, and CB then your going to still be using minoxidil, finasteride, then plus these new ones. Your always going to want more stuff versus less because its always stronger to use more.
At a point your going to ask is mortgaging your house to pay for male pattern baldness treatments worth it? This is just maintaining we are talking too. At this point I agree a cure isnt even worth mentioning. Id guess 20 years or more easily if ever in our life times. Stem cell stuff has articles from like 2004 and stem cell advances arent even remotely close to mass production or reliability for joe smoe. Many decades IMO for hair to be completely grown from scratch or multiplied out. Not even debatable.

 

[Youngerman]

Brotzu lotion or Rivertown is going to work. Get ready

 

[Desmond_84]

Hope for Shisheido too ASAP...

http://news.biglobe.ne.jp/it/0627/mnn_160627_5205821981.html

Apparently they are moving forward , all that matters really.

Hypothetically speaking, if Replicel can at least halt further miniturisation, Androgenetic Alopecia is cured for guys in the NW3 category and below. Hair transplants can give you the touch ups needed to bring you back to NW1.

 

[Swoop]

Hypothetically speaking, if Replicel can at least halt further miniturisation, Androgenetic Alopecia is cured for guys in the NW3 category and below. Hair transplants can give you the touch ups needed to bring you back to NW1.

Yeah totally agree desmond. I'm just trying to survive now and with a bit of luck we'll have better maintenance options.

Hair transplants to fill up the rest indeed .

 

[Follisket]

I would have thought that hair transplant surgeons would do more business if they could:

1) Find a way to get more grafts (cloning?) -That would result in more business, no graft restriction/don't need to turn patients away
2) Stablise hair - gives people the confidence to go ahead with a transplant knowing it won't look out of place in the future.

Absolutely. And I'd add another thing:
3) Reliable prognosis - find a way of predicting with relative certainty a person's ultimate scope of baldness. That way you could at least do your math and know exactly what to expect before getting a hair transplant.

Ensuring just one of those three things would make all the difference. It's insane no one's yet accomplished either.

People keep saying hair loss research has made great strides and yet we've still not got a single safe and effective maintenance treatment or means of prognosis - how the hell could we even dream of a cure?

 

[abcdefg]

Well I dont want a hair transplant or any invasive procedure. I just want to keep the hair I have right now which should be 10 times easier then getting back huge amounts of hair, but we cant even do that yet. If we cant keep existing hair your never going to get a cure before that because a cure is going to be much harder

 

[Spellbinder]

What about replicel follicle cloning and planting. This seems like the most promising therapy in the future to me.

 

[orkun]

shideo norwood 7 and the DUPA have hope ?

 

[Follisket]

Even Replicel admits that after a certain point hair loss is irreversible. No hope past NW2,5-ish. The hair is gone. Dead. Over.

Still ok with waiting?

 

[Xaser94]

Even Replicel admits that after a certain point hair loss is irreversible. No hope past NW2,5-ish. The hair is gone. Dead. Over.

Still ok with waiting?

From Follica's patent

The following protocol describes a Phase Ila clinical study ......

[00638] Diagnosis and main criteria for inclusion are Caucasian males 20-65 years of age, providing written informed consent, who have androgenetic alopecia with the presence of a vertex transition zone defined as an area possessing both terminal and miniaturized hairs, Hamilton-Norwood type 3V, 4, 5, 5A, or 5V, with a vertex area large enough to accommodate both treatment sites, and Fitzpatrick skin type 1-4. "

"[00658] In dermabraded areas of skin, induction of neogenic-like hair follicles and activated, stimulated, or reorganized pre-existing (including vellus-sized) follicles was measured as detected and analyzed by skin biopsy analysis at Day 14. In contrast to what is generally found in unwounded scalp skin,the controlled perturbation in this study 1) induced neogenic-like follicles and 2) placed preexisting follicles into a reorganized and activated state. The structures of interest detected and counted in the Day 14 biopsies are observed only rarely in unwounded skin. Therefore, they are comprised of neogenic-like and activated, stimulated, or reorganized structures "

[00656] It was found that, for subjects treated with dermabrasion plus hydrogel:
• From baseline to Day 84 (3 months), target area hair counts (also referred to as "TAHC") of all hair show substantial increases that are statistically significant (see Table 9). This change in counts of all hair from baseline is maintained through the last day of measurement, Day 168 (6 months; See Table 10) and the change is statistically significant on Day 168.

This is from phase 2a so thy have seen regrowth even in higher norwoods, but they also claim there has to be a vertex transition zone which means that as long as u still have an island in the front and some in the back u should be good. I think if your norwood 6 and you olnly have hair from below the crown your probably not a candidate.

In this picture they are clearly using the dermabrasion on the temple though.

I also find it odd that Replicel mentioned regrowth was most likely possibly in the interview with Hellouser. So which one is it smh.

Histogen also showed that picture with that guy who got crazy regrowth. He clearly had regrowth in completely bald areas.

 

[Pray The Bald Away]

Follica

From Follica's patent

The following protocol describes a Phase Ila clinical study ......

[00638] Diagnosis and main criteria for inclusion are Caucasian males 20-65 years of age, providing written informed consent, who have androgenetic alopecia with the presence of a vertex transition zone defined as an area possessing both terminal and miniaturized hairs, Hamilton-Norwood type 3V, 4, 5, 5A, or 5V, with a vertex area large enough to accommodate both treatment sites, and Fitzpatrick skin type 1-4. "

"[00658] In dermabraded areas of skin, induction of neogenic-like hair follicles and activated, stimulated, or reorganized pre-existing (including vellus-sized) follicles was measured as detected and analyzed by skin biopsy analysis at Day 14. In contrast to what is generally found in unwounded scalp skin,the controlled perturbation in this study 1) induced neogenic-like follicles and 2) placed preexisting follicles into a reorganized and activated state. The structures of interest detected and counted in the Day 14 biopsies are observed only rarely in unwounded skin. Therefore, they are comprised of neogenic-like and activated, stimulated, or reorganized structures "

[00656] It was found that, for subjects treated with dermabrasion plus hydrogel:
• From baseline to Day 84 (3 months), target area hair counts (also referred to as "TAHC") of all hair show substantial increases that are statistically significant (see Table 9). This change in counts of all hair from baseline is maintained through the last day of measurement, Day 168 (6 months; See Table 10) and the change is statistically significant on Day 168.

This is from phase 2a so thy have seen regrowth even in higher norwoods, but they also claim there has to be a vertex transition zone which means that as long as u still have an island in the front and some in the back u should be good. I think if your norwood 6 and you olnly have hair from below the crown your probably not a candidate.

In this picture they are clearly using the dermabrasion on the temple though.

View attachment 41473

I also find it odd that Replicel mentioned regrowth was most likely possibly in the interview with Hellouser. So which one is it smh.

Histogen also showed that picture with that guy who got crazy regrowth. He clearly had regrowth in completely bald areas.

Follica won't work for dark skinned people since it lightens skin. I feel bad for african american and hispanic people.

 

[Xaser94]

Who cares about lighter skin when new hair covers it

 

[kuba197]

I have hope for s-equol and you will not make me pessimist again Just maintain my thick nw2!!

 

[atthekeysbored]

Even Replicel admits that after a certain point hair loss is irreversible. No hope past NW2,5-ish. The hair is gone. Dead. Over.

Still ok with waiting?

This is proven false in the swisstemples thread with westonci's regrowth in nw3.5 areas, not to mention the transexual who got full regrowth from significant balding. Or the old men who took unrelated medication and grew hair in nw7 zone.
The follicle is always there waiting to be reactivated, assuming you don't destroy it with a hair transplant.