Yes. I took it at a time where my hormonal profile wasn’t ideal. I had watery semen almost instantly, puffy nipples and fat gain. It isn’t the Estrogen, it’s just what this poison does to your liver and androgens. The androgen disruption itself causes the gyno. There is a small increase in total T for a while but there is also a monstrous elevation of SHBG so your total test means sh1t because your free T is now cut in half. On top of that, your prolactin is elevated and your adrenals go whack mode. Granted it doesn’t work with the same intensity in everyone but it will cripple anyone with low T due to depression/anxiety (not primary hypogonadal men). The body does try to get used to the drug and it balances eventually thus the true claims that testicular pain etc stop. But then T lowers, it doesn’t equally as fast as everyone but it does eventually and androgen receptors can wear off. This fcuking drug hits differently each fellow so you can never have a definitive answer, it’s a clear try and tell case. I just don’t see the logic behind it as it’s a drug u need to take all your life. Lifetime commitment to this drug is suicide. Plus it doesn’t really do a good job at stopping hair loss if the enzyme doesn’t respond as it should or if testosterone production is high in the first place.