A Pilot Split‐scalp Study Of Combined Fractional Radiofrequency Microneedling And 5% Topical Minoxid

[alscarmuzza]

Background
Various trials have been conducted on the management of male pattern hair loss (MPHL), but the outcomes often seem to be limited. Adjuvant therapies are urgently needed.

Aim
To evaluate the efficacy and safety of combined fractional radiofrequency microneedling (FRM) and 5% topical minoxidil in the treatment of male pattern hair loss.

Methods
In total, 19 Chinese men were enrolled in this randomized, controlled, split‐scalp trial. Participants received monotherapy with 5% topical minoxidil twice daily to one half of the scalp, while on the other half of the scalp the treatment with twice‐daily 5% topical minoxidil was combined with five sessions of FRM at 4‐week intervals. Mean hair count and hair thickness, global assessment by the investigators, subject self‐assessment and adverse effects were assessed.

Results
After 5 months of treatment, mean hair count increased from 44.12 ± 21.58 to 73.14 ± 25.45 on the combined‐therapy side and from 46.22 ± 18.77 to 63.21 ± 19.22 on the monotherapy side, while mean hair thickness increased from 53 ± 13 μm to 71 ± 15 μm and from 52 ± 16 μm to 66 ± 14 μm, respectively. Compared with the monotherapy side, the combined‐therapy side had a higher degree of improvement in both hair count (P = 0.01) and hair thickness (P = 0.02).

Conclusions
Combined treatment with fractional radiofrequency microneedle and 5% topical minoxidil could be an effective and safe treatment option for male pattern hair loss.
Source https://onlinelibrary.wiley.com/doi/full/10.1111/ced.13551

Fractional Radiofrequency Microneedle

 

[barfacan]

What about the needling alone?

 

[Jk1]

would this diy device work for rf microneedle ?

https://www.amazon.com/Portable-Anti-aging-Matrix-Therma-Fractional/dp/B00G48RK3C

are results similar better or worse than dermarolling ?

 

[Pephair]

I believe it. I just wish there was more description on how they did the needling, timing, etc.

 

[DanielDüsentrieb]

Quite impressive numbers. I would also be interested in the timing and the device they used.

 

[NotInmywatch]

how frustrating. we need studies that include microneedling alone to formally understand its effects. In mice it has been shown that when you needle "too much" , "too little", "too frequent", etc .... undesirable outcomes appear, from no hair improvement at all to frank fibrosis.


PMID: 27746638
PMID: 18472060

 

[NotInmywatch]

here is the study

http://docdro.id/lUQeQ8T

from methods:
For the other half of the scalp, FRM was added to the therapy. This was performed five times at 4-week intervals, using an FRM device (BodyTite, Derma Optic & Electronic Ltd, Chongqing, China) with a disposable tip. The treatment tip was 1 cm2 in size, and contained 49 insulated microneedle electrodes with a diameter of 0.25 mm each. The device delivered 1 MHz of bipolar radiofrequency pulses through the microneedles. The parameters in our study were power of 12 W, microneedle penetrating depth of 1.5 mm and pulse duration of 300 ms.

 

[Falsenine]

Man with all these studies supporting the same concept makes me believe follica will provide substantial growth

 

[DanielDüsentrieb]

Man with all these studies supporting the same concept makes me believe follica will provide substantial growth

Hopefully follica (or shiseido vor tsuji) will be the reason Generation y will be the first Generation to win the battle against baldness.

 

[Marcaronii]

Hopefully follica (or shiseido vor tsuji) will be the reason Generation y will be the first Generation to win the battle against baldness.

Please let that be true.

 

[MomoGee]

here is the study

http://docdro.id/lUQeQ8T

from methods:
For the other half of the scalp, FRM was added to the therapy. This was performed five times at 4-week intervals, using an FRM device (BodyTite, Derma Optic & Electronic Ltd, Chongqing, China) with a disposable tip. The treatment tip was 1 cm2 in size, and contained 49 insulated microneedle electrodes with a diameter of 0.25 mm each. The device delivered 1 MHz of bipolar radiofrequency pulses through the microneedles. The parameters in our study were power of 12 W, microneedle penetrating depth of 1.5 mm and pulse duration of 300 ms.

So in Layman's terms this just says a dermapen (frm) was used with a tip that has 49 needles and the treatment was done once every 4 weeks. Am I correct in assuming that the dermapens found on eBay do the same job? That terminology is kinda throwing me off.

 

[NotInmywatch]

So in Layman's terms this just says a dermapen (frm) was used with a tip that has 49 needles and the treatment was done once every 4 weeks. Am I correct in assuming that the dermapens found on eBay do the same job? That terminology is kinda throwing me off.

in the article they make very clear that the radiofrequency that the needles emit, causes additional damage than needles alone, by generating heat and molecular vibrations, followed by posterior rupture of cells (thermolysis). it's basically the same that a microwave oven does to your food.

but the principle remains the same, causing calculated injury, inducing minimal amounts of inflammation, wait for the body to repair itself through the local release of healing/growing factors and hoping for the hair bulb/root to be exposed to this "good" molecules.

 

[BalderBaldyBald]

Sold by the same Chinese electronic supplier

https://dermamedical.en.ec21.com/Low_Level_Laser_Therapy_Laser--3379949_6848681.html

Sh4dow spy LLLT

Can't find the real product they used though

Edit :
Something like may do the deal this but specs are limited on eBay and i'm lazy to do more research
https://www.ebay.com/itm/Microneedl...quency-for-skin-tightening-wrin-/332026800371

Can't wait for Brotzu potion

 

[champpy]

Man with all these studies supporting the same concept makes me believe follica will provide substantial growth

But, will follica halt hairloss?

 

[NotInmywatch]

RF microneedling equipment is pretty much standard by now, you can find many devices on the market:

https://www.alibaba.com/product-det...tml?spm=a2700.7724857.main07.1.2f12f060OwqRt3

etc
what we need to know is if it works by itself (no minoxidil) and a well standardized protocol.

 

[Falsenine]

But, will follica halt hairloss?

I have no idea man, but I’m hoping it can provide some regrowth, I think it will be a good adjuvant treatment alongside min and finasteride
Who knows? Maybe it can create follicles in the donor area, now that would be a game changer in the hair transplant business. A couple of thousand additional follicles available for transplant would make a huge cosmetic improvement but I’m just speculating here.

 

[BalderBaldyBald]

Last real interview of Cotsarelis clearly stated that actual treatments will most likely have to be continued (Big 3), Follica is no cure, last published results were mentioning 25/hairs cm² increase and treatment can be repeated, patent is on Google

 

[Trichosan]

The Infini is the choice apparently among plastic surgeon offices and medspas. At least you can compare specs to other machines.

https://us.aesthetic.lutronic.com/u...MI5dmd-OX52wIVBGx-Ch3RPAZ1EAAYAyAAEgKYivD_BwE

 

[Jk1]

what about such a device ?

https://au.dhgate.com/product/usa-p...1kD03HVeTLuyHPpIL6oJf1N3GQMKrgHRoCatcQAvD_BwE

portable and handhled.. price is similar to a derminator... the qn is will this work as good as dermarolling or derminiator? or better as it goes deeper ?

 

[NotInmywatch]

what about such a device ?

https://au.dhgate.com/product/usa-portable-personal-use-thermage-beauty/209181795.html?utm_source=pla&utm_medium=GMC&utm_campaign=sunshinefullhose&utm_term=209181795&f=bm|209181795|018015|GMC|228938908|pla|sunshinefullhose|AU|018015017|c||2|&gclid=CjwKCAjw1ZbaBRBUEiwA4VQCId70bNYb7XTVeuI7-NnWQ11kD03HVeTLuyHPpIL6oJf1N3GQMKrgHRoCatcQAvD_BwE

portable and handhled.. price is similar to a derminator... the qn is will this work as good as dermarolling or derminiator? or better as it goes deeper ?

that thing doesn't even appear to have needles at all. the article was very clear in describing the synergistic properties of wounding (needles) and RF combined together.