SMI competes for the receptor - which is basically impossible to out compete for. BAY completely silences the receptor so there is zero activation.how does work compared to SMI and WAY?
SMI competes for the receptor - which is basically impossible to out compete for. BAY completely silences the receptor so there is zero activation.how does work compared to SMI and WAY?
What do she mean “applicant body test”?Im from china. One good thing is that they just established the new labs and they are going to start the HMI-115 human clinical trials against Hair l loss.
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The email feedback from professor xiao in English is" :
Thank you for your attention to my research. The results of the red-faced monkey are exciting and are currently being applicant body test. Hope to have good news to share with you in the near future.
good luck,
Xiao Ruiping 2021.9
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That’s great news . ThanksSorry for my translation. I mean they are now applying for the human experiment.
As I mentioned earlier, treating hair loss is not their main goal. You guys are getting your panties wet for something that maybe will be just a footnote for the researchers.
The ONLY company that managed to pull decent funding to treat SPECIFICALLY hair loss in the history of the universe is Stemson
Sounds like they've submitted their trial design for approval, which is pretty much the same answer the last person who emailed her received back. I'm assuming this was submitted in AustraliaWhat do she mean “applicant body test”?
Most likely they submitted both at the same time . Hopefully they get approved within the next couple weeksSounds like they've submitted their trial design for approval, which is pretty much the same answer the last person who emailed her received back. I'm assuming this was submitted in Australia
It's just a poor google translation for "human trials".What do she mean “applicant body test”?
Why would they mention Androgenetic Alopecia in an Endometriosis trial? They just got approval for Endo quicker then Androgenetic Alopecia, but the Androgenetic Alopecia will come soon.“
This study aims to evaluate the safety and efficacy of HMI-115 versus a placebo in pre-menopausal women with moderate to severe Endometriosis associated pain.
The study will have two parts: Part 1 and Part 2. Part 1 will determine the safety and efficacy of HMI 115 at 60 mg, 120 mg, and 240 mg. Only when the safety and efficacy have been evaluated by the Sponsor in Part 1 of the study will eligible subjects (new subjects) be admitted to Part 2 of the study. Part 2 of the study will determine the safety and efficacy of HMI 115 at 480 mg every 4 weeks (Q4W) and every 2 weeks (Q2W).
“
ClinicalTrials.gov
clinicaltrials.gov
No mention about Androgenetic Alopecia
Sorry for my translation. I mean they are now applying for the human experiment.
I was just surprised because it seemed like the main reason they bought rights to the drug was because of its potential for treating Androgenetic AlopeciaWhy would they mention Androgenetic Alopecia in an Endometriosis trial? They just got approval for Endo quicker then Androgenetic Alopecia, but the Androgenetic Alopecia will come soon.
Right. Nobody should be surprised that a serious condition got approval faster than male pattern baldness, nor that the FDA moved faster than the TGA in Australia. They probably submitted both trials and the same time, and perhaps even submitted the Androgenetic Alopecia trial first.Why would they mention Androgenetic Alopecia in an Endometriosis trial? They just got approval for Endo quicker then Androgenetic Alopecia, but the Androgenetic Alopecia will come soon.
There's more money in endo for this company then there is for hair loss unless this turns out to be a full stop cure. Endo effects up to 10% of women and the current treatments involve trying to cold-burn the problem away with a nitrogen stick. The treatment would be covered by insurance and the company would be charging tens of thousands easily. For hairloss, not many people will be lining up to spend 20k+ yearly for a slightly better minoxidil or finasteride. There's more financial risk if the trials don't go perfectly.I was just surprised because it seemed like the main reason they bought rights to the drug was because of its potential for treating Androgenetic Alopecia