Breezula Positive Phase 2 Result For Treat Androgenetic Alopecia

[iSlapBitches]

yeah sure that duta is not the reason your hair looks good.

You wish dude. I had already been on duta for three years (and finasteride three years before that) before adding RU. Pretty easy to note what causes the change when you only change one variable.

Duta is needed though because they work together through different mechanisms. Neither ru or duta alone will stop your hairloss if it’s even mildly aggressive, but together they are magical.

 

[inmyhead]

You wish dude. I had already been on duta for three years (and finasteride three years before that) before adding RU. Pretty easy to note what causes the change when you only change one variable.

Duta is needed though because they work together through different mechanisms. Neither ru or duta alone will stop your hairloss if it’s even mildly aggressive, but together they are magical.

Look at other people experience using that - forum is full of people with no results.
You are also super defensive for RU - you even went through my post history to dislike my posts. It seems that even you aren't sure if RU works for you? Sad guy.

 

[iSlapBitches]

Look at other people experience using that - forum is full of people with no results.
You are also super defensive for RU - you even went through my post history to dislike my posts. It seems that even you aren't sure if RU works for you? Sad guy.

Those are some big logic jumps you’ve made there but whatever. Just trying to help you guys out. I’ll enjoy my nw0 and you enjoy whatever you have lol.

 

[Kagaho]

RU has a higher affinity for the Androgen Receptor than CB, for example,

If used twice per day at a concentration of 5%, i think it can reach propecia levels of efficacy.

If you are also on Dutasteride, man thats a powerful regimen

 

[washed_up]

RU has a higher affinity for the Androgen Receptor than CB, for example,

If used twice per day at a concentration of 5%, i think it can reach propecia levels of efficacy.

If you are also on Dutasteride, man thats a powerful regimen

The results in this trials using CB 7.5% once a day show better than propecia efficacy.

 

[Kagaho]

The results in this trials using CB 7.5% once a day show better than propecia efficacy.

Yeah, i read the press release. I would prefer to wait for the final results though.

I think antiandrogens effectiveness should be reviewed by the percentage of people whose hair count dindt fall dramatically over a long period of time (5 years or more).

Even castration cant regrow much hair

 

[washed_up]

Yeah, i read the press release. I would prefer to wait for the final results though.

I think antiandrogens effectiveness should be reviewed by the percentage of people whose hair count dindt fall dramatically over a long period of time (5 years or more).

Even castration cant regrow much hair

I don't think this is being marketed as a regrowth drug. It's strictly about prevention. Like you were saying, if you combine a topical approach with a systemic inhibitor of some kind, the amount of DHT and test in your scalp will be so minuscule that you may not lose any more hair for a long, long time.

 

[Kagaho]

I don't think this is being marketed as a regrowth drug. It's strictly about prevention. Like you were saying, if you combine a topical approach with a systemic inhibitor of some kind, the amount of DHT and test in your scalp will be so minuscule that you may not lose any more hair for a long, long time.

I hope thats the case.

I do not want to underestimate Breezula. I believe that if it is confirmed that it is a safe drug, it will outperform Propecia and Avodart in sales.

Probably many doctors can prescribe it to young patients even as a preventive measure. Thats also pretty good

 

[NotInmywatch]

I hope thats the case.

I do not want to underestimate Breezula. I believe that if it is confirmed that it is a safe drug, it will outperform Propecia and Avodart in sales.

Probably many doctors can prescribe it to young patients even as a preventive measure. Thats also pretty good

I agree. Although DHT is the main killer, Testosterone also binds to the AR and most likely contributes, in a lower degree, to the hair massacre.
Blocking the AR without ruining your body should be more effective than any 5-alpha reductase blocker by definition.

 

[iSlapBitches]

I don't think this is being marketed as a regrowth drug. It's strictly about prevention. Like you were saying, if you combine a topical approach with a systemic inhibitor of some kind, the amount of DHT and test in your scalp will be so minuscule that you may not lose any more hair for a long, long time.

Yup, that’s essentially what I do now with RU and dutasteride. Add in minoxidil and the derminator for dermarolling and ive got f*****g amazing hair. Anyone who doesn’t at least try this to see if they get sides or not doesn’t want to keep their hair.

 

[Heat06]

Yup, that’s essentially what I do now with RU and dutasteride. Add in minoxidil and the derminator for dermarolling and ive got f*****g amazing hair. Anyone who doesn’t at least try this to see if they get sides or not doesn’t want to keep their hair.

Why did you drop Propecia after 3 years? I tried RU, but it had this weird side effect with my eyes. Would turn them bloodshot if I used it daily.

Where do you get your RU and how do you mix it with your minoxidil? Curious because I currently use the foam and would be interested in trying this if it could regrow and thicken my existing hair.

How often do you apply? AM or PM?

Everything I’ve heard about RU since I tried it has been negative and causes side effects. You’re the first person I’ve seen who remains adamant it works effectively.

Also, did you experience any sides while on Propecia? What about when you switched to dutasteride? I may need to step my game up from the 0.5mg of Propecia and minoxidil I’m currently taking now.

 

[iSlapBitches]

Why did you drop Propecia after 3 years? I tried RU, but it had this weird side effect with my eyes. Would turn them bloodshot if I used it daily.

Where do you get your RU and how do you mix it with your minoxidil? Curious because I currently use the foam and would be interested in trying this if it could regrow and thicken my existing hair.

How often do you apply? AM or PM?

Everything I’ve heard about RU since I tried it has been negative and causes side effects. You’re the first person I’ve seen who remains adamant it works effectively.

Also, did you experience any sides while on Propecia? What about when you switched to dutasteride? I may need to step my game up from the 0.5mg of Propecia and minoxidil I’m currently taking now.

I dropped propecia after 3 years to switch to dutasteride. They both work they just don’t completely stop hairloss because they don’t stop all dht from converting from test and harming your hair. You need a topical antiandrogen which helps stop that remaining dht from causing hairloss.

I get my ru from Kane’s shop and I mix it by simply pouring it in the minoxidil bottle and shaking the hell out of it. Store the bottle in the fridge. I apply ru/minoxidil in both am and pm.

I can understand that other may get side effects on ru, I don’t. It definitely works well but I’m very admatant that it should be used with finasteride/dutasteride and not as a replacement for them. It has a synergistic effect because they work through different mechanisms to fight dht in our hair.

No sides on either propecia or dutasteride except watery semen when first starting out on propecia. Also I had an abnormally high sex drive when I first started dutasteride.

 

[Heat06]

I dropped propecia after 3 years to switch to dutasteride. They both work they just don’t completely stop hairloss because they don’t stop all dht from converting from test and harming your hair. You need a topical antiandrogen which helps stop that remaining dht from causing hairloss.

I get my ru from Kane’s shop and I mix it by simply pouring it in the minoxidil bottle and shaking the hell out of it. Store the bottle in the fridge. I apply ru/minoxidil in both am and pm.

I can understand that other may get side effects on ru, I don’t. It definitely works well but I’m very admatant that it should be used with finasteride/dutasteride and not as a replacement for them. It has a synergistic effect because they work through different mechanisms to fight dht in our hair.

No sides on either propecia or dutasteride except watery semen when first starting out on propecia. Also I had an abnormally high sex drive when I first started dutasteride.

I appreciate you sharing. How much RU do you buy from Kane (amount you pour into each minoxidil bottle)? Also, what brand minoxidil do you use?

I desperately need to add something else to my regimen because I’m losing ground. I can’t take the full 1mg of Propecia because of sides so I have to stick with 0.5mg daily, but I may try RU again if it can help.

 

[Jk1]

The results in this trials using CB 7.5% once a day show better than propecia efficacy.

this is big news isnt it ? that a topical has been proven to work as good or better than propecia !

Also how does this compare to minoxidil 5% results ? better or worse.

The reason this is important is that it shows that topicals can work and WITHOUT an internal DHT. So that means any other topical that were ignored in the past may deserve a better look at now ! as it was always assumed u need an internal DHT inhibitor.

 

[jamesbooker1975]

@jamesbooker1975
you even say it yourself :
"Testoterone --------DHT-------- HIGH PDG2 ------Baldness"
so who needs a pgd2 receptor antagonist or anti histamine when you have a drug which prevent dht to interact with HF in the first place? Have you even read what I posted about The mechanism of action of breezula? That said , Im already applying several topicals sooo ONE unique treatment for me is a cure even if I have to apply it twice daily. Gosh I would drop all my current regimen if a truly effective treatment(maintenance + fair regrowth) comes on the market and leave this forum for good like most of us. (and maybe a little hair tranplant for the sake of it) Now for almost slick bald people that's maybe another game and the cure should come later.. tsuji...

Why, really? Let me explain you. This drug, Breezula or whatever they want to call it, it is an antiandrogen. Meaning, if is absorbed , and you try to know it by a meassure of DHt, Testerones, Estrogen levels ( like they did ) you will not now it. Cause antiandrogen don't lower androgens levels, is simple block the site.

Second, you say " well , I will drop everything for a 2 times application ". Can I ask you for how long you have being with male pattern baldness ? 23 years and counting. Believe, the hair lotion don't give you a good aspect to your hair when you put it in .
You will say " hey , no problem, HM is around the corner " Well, I have being heard that since 1997 .

And by last, this is a very small company, that advance extremely slow. Just now they put the name for the drug ! If they start phase 3 in 2020 ( forget 2019 ) will be a miracle.


By last , they are comparing this to propecia instead of dutasteride, and even so, the results are not dramatic ( dutasteride, side effeces aside , keep breezula *** )

 

[jamesbooker1975]

I appreciate you sharing. How much RU do you buy from Kane (amount you pour into each minoxidil bottle)? Also, what brand minoxidil do you use?

I desperately need to add something else to my regimen because I’m losing ground. I can’t take the full 1mg of Propecia because of sides so I have to stick with 0.5mg daily, but I may try RU again if it can help.

Sorry pal to heard it. But if you dropped Finasteride cause side effects, going to China homemade Ru ( a drug never testes in humans ) is not a brilliant. . You can try ketoconazole cream ( not shampoo, leave it the entire night ) , alpha estradiol , etc.

 

[jamesbooker1975]

Back from 2008, yep, 10 years ago : Cosmo initiates phase I trials of CB-03-01 aka breezula aka whatever name you wanna call it, for the treatment of skin disorders
http://www.cosmopharma.com/~/media/...news/press/pr2008/2008-04-01/2008-04-01en.pdf

Yes, yes, another company, another small company too.

 

[washed_up]

Back from 2008, yep, 10 years ago : " Cosmo initiates phase I trials of CB-03-01 for the treatment of skin disorders"
http://www.cosmopharma.com/~/media/...news/press/pr2008/2008-04-01/2008-04-01en.pdf

Yes, yes, another company, another small company too.

I don't understand what you're saying.

 

[jamesbooker1975]

I don't understand what you're saying.

really. Ok, Jak inhibitors, the one using in Areata ( for example ) ,this specific molecule used as topical was patent less than 4 years ago, and they are ending phase 2. Breezule, CB-03-01 or how the hell you want to call it, was patented 14 years ago. Now, you have a better idea why there is great chances that this breezula goes nowhere ?

 

[alibaba92]

I don't understand what you're saying.

what he was trying to say is that the CB 03 01 had been there for such a fuking long time, 10+ years, and now, still in trial. So, he deduces that Breezula will end up nowhere.

@jamesbooker1975, I think no body out there really cares about Androgenetic Alopecia cause it does not kill man and yet, the common assumption is that men dont give a fuk to how they look, thats why every thing related to Androgenetic Alopecia are all delayed.