Cassiopeia Release Full Year Results To 2018 Including Update On Breezula

vinnievandall

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Well i want to see evidence with my own eyes. I will make 4 bottles 3 with only the vehilcle and 1 with the cb i will ask my wife to number each bottle and to remember wich number is with the cb. I will use them all for 2 weeks this way im going to know for sure if it is a placebo or not
 

vinnievandall

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f*** off just because there is more people who suffer from mental illness doesn't excuse yours
From what i can read your the one with a mental illness mate.. I got f*****g sides you cant even f*****g imagine red eyes surely placebo huh like its out there for eveyone to see even got comments on it f*****g b**ch wanker go jump on someone elses dick just because you dont get sides from your f*****g tranny drugs doesnt mean sides are imagined. I wished i could swap bodys for a day so you could feel what im felt stupid dickshit
 

vinnievandall

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you are clearly mentally insane. CB does not cause such side effects, it's absolutely ridiculous. im sure do did get some effects however you can't attribute that to the CB but rather to your mental health status most likely. why do I think that? because you specifically claim CB caused it, not the possible impurities. you are so confident that the CB caused it. but I tell you one thing, isn't it funny that thousands of people are fine on CB in the studies, a compound that has zero systemic androgen effects and who's metabolite cortexalone is weak as glucocorticoids, much much weaker than cortisol which itself could not possibly cause this kind of reaction. maybe you want to see a doctor? before you blame it on a well researched chemical that has been tested in probably higher dosage on school children. nobody gets sides and not only do you get small sides, you get a full blown massive reaction to it. what a coincidence that people on the hairloss forum get all the side effects. did they fake the studies? you have to know how statistically insane it would be to go from a 0% side effect rate in the studies to basically 50% on HairLossTalk.com. and you don't think insanity plays a role in that? how laughable
Believe whatever you want mate btw there was a 0% sexual side effect rate and that was true no sexual sides .. Where did you even got the info they where testing it on children? I dont see this happening they are not going bald.. Maybe for winlevi a 1% CREAM ofcourse you wont get sides from such thing it barely penetrates the skin
 

byebyehair

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lol you people have such mental illness, you would get sides from f*****g gummy bears if I told you they can treat your hairloss. this si absolutely unreal, nobody of 3k people in a study gets sides, random idiot from HairLossTalk.com gets side, huhuhuh it must be the CB, can't be my brain no that can't be the case at all
gummy bears killed my libido. And they made me watch killing my libido :(
 

Baldy12345

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From what i can read your the one with a mental illness mate.. I got f*****g sides you cant even f*****g imagine red eyes surely placebo huh like its out there for eveyone to see even got comments on it f*****g b**ch wanker go jump on someone elses dick just because you dont get sides from your f*****g tranny drugs doesnt mean sides are imagined. I wished i could swap bodys for a day so you could feel what im felt stupid dickshit
This is the type of dude to claim chest pain from a glass of milk. Research has proven that cb doesn’t go systematic and doesn’t cause sides. However, people still claim sides. If bananas were proven to cure baldness, people on this forum would still claim a drop in libido.
 

1knox1

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I can’t vouch for or against @vinnievandall but I guarantee if/when cb comes out, loads of guys are going to get placebo effects.
 

1knox1

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for sure. the mods will need to employ someone new otherwise they can't manage banning all those people properly

Moaning about finasteride is a big one atm. I understand that people probably do get sides from it but when they try and call it things like ‘dick killer’.... bla bla, just because it doesn’t work for them; yet they will put endless posts in the new research section about vitamin d and scalp massages.

We are all meant to be on the same side here.
 

I could hair less

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you are clearly mentally insane. CB does not cause such side effects, it's absolutely ridiculous. im sure do did get some effects however you can't attribute that to the CB but rather to your mental health status most likely. why do I think that? because you specifically claim CB caused it, not the possible impurities. you are so confident that the CB caused it. but I tell you one thing, isn't it funny that thousands of people are fine on CB in the studies, a compound that has zero systemic androgen effects and who's metabolite cortexalone is weak as glucocorticoids, much much weaker than cortisol which itself could not possibly cause this kind of reaction. maybe you want to see a doctor? before you blame it on a well researched chemical that has been tested in probably higher dosage on school children. nobody gets sides and not only do you get small sides, you get a full blown massive reaction to it. what a coincidence that people on the hairloss forum get all the side effects. did they fake the studies? you have to know how statistically insane it would be to go from a 0% side effect rate in the studies to basically 50% on HairLossTalk.com. and you don't think insanity plays a role in that? how laughable

of course you also got sides on finasteride which in itself is pretty rare, only 5% of men get sides on finasteride but not just that, CB is a completely different compound and it's byproducts are completely different. it's kind of a strange occurrence that you would have such a heavy reaction to that as well. have you tried minoxidil? do you get chest pain on minoxidil as well? see, some people do claim do get chest pain and heart palpitations on minoxidil even though systemic absorption is 1/3000 of what you get with the tablet. so that claim is outrageously insane, just like yours


have you tried CB yourself????
 

I could hair less

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no but I can read. frankly it wouldn't make a difference if I tried it myself, I know people who have and have been completely fine so whats your point? the science is clear and anybody has to admit how absolutely insane this sounds. i haven't tried it but 3 thousand others have and they haven't had any side effects. so what now? duh

and 2,000 ppl in the Propecia trials also didn't get sides but yet we know finasteride sides are close to 30%...

not to mention the length of the studies havnt been so long...but go on thinking this topical is gonna cure your crappy life
 

vinnievandall

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Whats rezlly funny is i read so much scare mongering about minoxidil yet i got no side effects i read everywhere cb should be safe and have non and i got side effects some pretty crazy placebo going on with me if you ask me also didnt had sides on topical spironolactone or on brotzu scam yet in the middle of the day when im not even thinking about anything hair related while making music bang stabbing chest pains. And im not saying you could not be right because i dont have the purity reports yet but still its very questionable if you ask me.
 

Btg

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what actually would be funny is seeing the full year results instead of side effects arguing
 

I could hair less

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you didn't get sides from minoxidil because it is literally not possible. what I find veery questionable is that CB has no systemic activity which has been verified in a lab, it has not caused side effects in thousands of people including children and is deemed safe enough to be moving forward with nda and some randos on the internet get serious side effects that are unheard of in any major study. maybe you should actually see a doctor and let them do tests, ask them what the chest pain should be caused by. I find it ridiculously unlikely to be caused by CB

again shows you know nothing..minoxidil can increase BP and cause other issues, rare and not super serious but you show ignorance again...
 

ZenHead

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Sorry to butt in here, but it is very possible that the CB sides we are discussing are caused by impurities in the batch. I’m not taking anyone’s side here, I’m just saying it’s possible and something to think about. I’m not claiming that CB is impossible to cause sides, finasteride fucked me up on 2 separate tries. It is possible with antiandrogens, and we don’t have enough data yet. But things other than sexual sides with CB could be caused by impurities by shitty Chinese manufacturers. It’s happened before.
 

ScaredOfBalding

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Whats rezlly funny is i read so much scare mongering about minoxidil yet i got no side effects i read everywhere cb should be safe and have non and i got side effects some pretty crazy placebo going on with me if you ask me also didnt had sides on topical spironolactone or on brotzu scam yet in the middle of the day when im not even thinking about anything hair related while making music bang stabbing chest pains. And im not saying you could not be right because i dont have the purity reports yet but still its very questionable if you ask me.
The fact that u can't even write coherent sentences tells me u are mentally fucked m8.
 

HairSuit

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lol give me a break. whats more likely, casiopea doing 5 fraud studies that are accepted as valid by the fda so they get a waiver and can apply for fda or some guy on the internet who claims sh*t all over the place from insomnia to painful limbs to red eyes and chest pain, to loss of libido. whats more likely, whats more credible? in the last week i have read countless of tresses posts about minoxidil and giving them heart issues even though that is scientifically not possible if you don't bath in it because systemic absorption is a thousandth of what is taken by tablet in the treatment of blood pressure issues. it's just that people learned that minoxidil was used to treat blood pressure and acted accordingly. thats what happened. when people found out is being metabolized to cortisol they got cortisol related sides. just that it is not actually metabolized to cortisol but cortex alone which a a lot weaker and basically inactive at that dosage.

I posted a link a couple of minutes ago about a guy using 0.6% of CB who claims to got massive insomnia and chest pain from it, that percentage is like a tiny amount of what children were exposed to in the stage 3 acne trial for 12 months. hardly likely that anything but placebo has caused this issue. and especially because hamster models have show that CB is inactive even if it is INJECTED under the skin. putting it on the skin makes it even better
@petersonKj We agree on the safety profile of CB. However.... let’s also not think that these drug companies are the pillars of honesty, either. God knows Merck added side effects to the profile that were never included in the original testing. They are trying to get a drug approved. I sure hope they do, but it would not be beyond the scope of things for them to be less than forthcoming with whatever they can squeak by with.
 

Lucky_Luciano

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lol this is amazing. minoxidil does increase BP taken in according doses and orally. topically applied, 1/3000th(actual number) of the minoxidil goes systemic compared to the oral tablet you would take if you were to treat your blood pressure. so, funny enough, it turns out you don't know what the f*** you are talking about and are just an internet scientist after all
Man i logged in just to write that you are a spreading wrong information retard. Minoxidil does go systemic, I used it few years ago a short time for beard growth and it gave me heart palpations and lowered blood pressure so I was feeling tired and sleepy afterwards. And I’ve seen tons of reports on the internet claiming the same. Dark cirkles, skin aging and hypertrichosis also arent rare.
 

HairSuit

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have you all gone conspiracy theorists now? merck did not include stuff like depression in the original study because it did literally not occur int heir study. there is absolutely no evidence that they frauded that data, it's not hard to believe either since since then, many studies have come to the same conclusions when it comes to the safety profile of finasteride, even those critical of it have not found that strong of a correlation with depression and finasteride. people who don't tolerate finasteride go completely bonkers against merck for whatever weird reason(merck doesn't even sell much of it anymore it's all generics)

and how would cassiopeia actually go about doing this? you think they'd literally risk anti androgenic action in children? that would be their end lol. and do you know how the fda reviewing process works? you can't just hide a bunch of people who got red eyes chest pain and severe limb pain so that they had to withdraw from the study. you know thats completely absurd right?

these things as the ridiculous people on thsi forum claim to get from CB does not go unnoticed in a study.

like do you actually believe this sh*t on this forum? come on. you think every second guy on HairLossTalk.com gets side effects that forces them to discontinue and this could go completely unnoticed in their studies? what about the hamster study where they literally showed that CB does not have any systemic anti androgenic activity and that the levels of rising cortexalone are extremely low comparatively?

I swear, once this comes out there will be a sh*t load of posts about side effects here and it will discourage people from treating themselves just as it does now with finasteride. and people will blame it on the company instead of on the high neuroticism of the guys here
Do you really think that a drug company would add something to to the side effect profile that would work against their selling said drug? If I’m not mistaken, it took them over a decade to do so. Because eventually, they can’t deny it anymore. But rest assured, they will wait as long as they can. It’s not conspiracy theory. It’s reality. I’m not saying finasteride will grow a second head, I’m saying they are protecting their bottom line. Plain and simple.
 

HairSuit

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God dude. You are blowing your credibility. Truly. Some of us have been around here and seeing patterns and anecdotal experiences for over a decade. You coming on here and spouting off what you think to be truth, doesn’t change history. You’re default is accusing everyone of having “mental issues” and being “insane”. You have zero objectivity, and time will prove you wrong. There’s been a ton like you in the past, you’re just a number. Be constructive, or just don’t post, because your endless rants and accusations against people that may have a different opinion or experience than you, only serves to make you background noise.
 

hilbert

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imho the truth might be in between, as usual.
a. the more a company has spent in an NCE, the more they are likely to conceal sides or defects (reason why I trusted the early CB trials: they had little to lose then)
b. fora do not run double-blind trials; we dont even know when sides are due to fake/impure chemicals from china, or to nocebo, etc.

re. CB: it's likely it will have a bit more sides than reported by the clinical trials, and less than reported by fora.
 

HairSuit

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lol. here is what should actually concern people, that this sh*t treatment is still most likely 4 years away optimistically speaking. they want to start enrollment for their phase 3 trial in Q4 2019, enrollment for phase 3 winlevi started in Q4 2016 which means breezula is pretty much exactly 3 years behind winlevi. winlevi will not come out before the end of 2020, probably Q4. so we are looking at a potential release of CB for Q4 2023 if everything goes well. thats still 4.5 years away, absolutely insane if you ask me. im basically trying to forget about this treatment altogether, it's just a sick joke that people have to wait to the midth of the 2020 for a topical androgen, thats absolutely embarrassing.

this company is running out of money, it's dying and I would not even be surprised if this sh*t never reaches market and gets stuck in patent limbo for the rest of the first half of century.

they are smart though, I followed them, they had 2019 release initially and 2021 for breezula. then they changed it to Q42019/Q12020, then to H1 2020 and now it says just 2020 lol.
people don't realize this but even 2022 which is already morbidly depressing is unrealistic for CB to reach the market. it will take winlevi 4 years to go from enrollment of phase 3 to market release, I really don't see the point anymore in any of this.

maybe you are right, maybe I am naive but hair loss research is the single most pathetic thing I have seen in my life

I am quite confident there will be further delays especially if you read their announcements in order, every year half a year is added to the timeline.

then again, I am from sh*t hole europe and this treatment won't even be on this market before what, 2025? why not make it 2030? why not wait until 2040 to bring out a topical androgen, that'd be fun. you literally can't make this sh*t up, the best thing to look forward to now is a topical anti androgen that is in the most realistic case 5 years away to be available on the european market. anybody who doesn't get clinically depressive with this in mind has lost theirs.
This, we agree on. And well put. It’s frustrating. They have us by the short and curlies, unfortunately.
 
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