Clonin' update. Interctyex interview with Dr. Paul Kemp
- Thread starter michael barry
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powersam
Senior Member
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as my understanding is quite limited i'm probably wrong, but i was under the impression that they injected a cell culture which would then form into whatever that part of the body told it to form into. as it was injected into the scalp it would form into a hair follicle. just throwing it out there.
hairfin
Established Member
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ok let me get this straight, if he's saying you need to take finasteride in order to make sure your hair doesnt thin over time like a older persons would then HM would be ok as i dont want a full thick head of hair at 60 or so, i dont mind nature takings its course then and both the top and back/sides thinning over 40-50-60 etc
But if he's saying that you need to take finasteride in order to maintain the new HM hair (otherwise itll start thinning straight away) then i would be excluded as the sides are too much for me.
anyway its only a few years away so we wait in eager anticipation! (with early phase 2 stuff filtering it mid 2007)
But if he's saying that you need to take finasteride in order to maintain the new HM hair (otherwise itll start thinning straight away) then i would be excluded as the sides are too much for me.
anyway its only a few years away so we wait in eager anticipation! (with early phase 2 stuff filtering it mid 2007)
michael barry
Senior Member
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I cannot believe that some of you are not willing to read the entire interview. Like a bunch of spoilt children waiting for the Wizard of Oz to give you your hair back maintenance-free....................
htownballa wrote that he didn't see what wreath hair had to do with HM.
HOW ABOUT EVERYTHING HTWONBALLA> Where do you think they are getting the stem cells from? They will be extracting approximately 120 hairs from YOUR HEAD surgically. They will isolate some dermal papilla and outer root sheath cells. They will have DP cells, and a few stem cells in this mixture. They will make these cells multiply in a petri dish over a few months..................................making many many more than what was extracted surgically. They will then shoot your scalp with the cells derived from your hippocratic wreath hair.
Even notice how bald men's wreath hair greys and thins with age while women just keep their hair. LOOK HARD AT DR. PHIL. Even your wreath hair has a "slight" sensitivity to male hormone. Wreaths do thin on bald men as they get progressively older. Its best to still use propecia and rotate nizoral shampoo as an anti-androgen routine even after HM so your hair doesnt thin out somewhat and prematurely grey and get brittle/agey on you.
Only way to have hair all your life maintenance-free is to pick the right parents. The rest of us have to work at it.
htownballa wrote that he didn't see what wreath hair had to do with HM.
HOW ABOUT EVERYTHING HTWONBALLA> Where do you think they are getting the stem cells from? They will be extracting approximately 120 hairs from YOUR HEAD surgically. They will isolate some dermal papilla and outer root sheath cells. They will have DP cells, and a few stem cells in this mixture. They will make these cells multiply in a petri dish over a few months..................................making many many more than what was extracted surgically. They will then shoot your scalp with the cells derived from your hippocratic wreath hair.
Even notice how bald men's wreath hair greys and thins with age while women just keep their hair. LOOK HARD AT DR. PHIL. Even your wreath hair has a "slight" sensitivity to male hormone. Wreaths do thin on bald men as they get progressively older. Its best to still use propecia and rotate nizoral shampoo as an anti-androgen routine even after HM so your hair doesnt thin out somewhat and prematurely grey and get brittle/agey on you.
Only way to have hair all your life maintenance-free is to pick the right parents. The rest of us have to work at it.
person_123
Established Member
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side and back hairs thin out. they are still affected by dht, but not as much as crown or hair line hair. that's why they still get thinner (for some people) but you don't go bald around those areas.
i'm guessing it's something to do with the androgen receptors there, they're 50% functional, whilst our crown hair is 90% androgen receptive.
i'm guessing it's something to do with the androgen receptors there, they're 50% functional, whilst our crown hair is 90% androgen receptive.
elguapo
Experienced Member
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person_123, we don't REALLY know that the side and back hairs are affected by DHT. I mean, don't get me wrong, I think that is the case as well, but maybe it is something else, maybe they thin out for a different reason.
That's what I like about the design of the Phase II trials. I think it will answer a few of these questions.
I mean, for one, it is really interesting that 2 out of those 7 in the Phase I trials did not regrow hair. Let's assume that they did not regrow any hair, which I'm not sure is explicitly stated, but let's assume that. And the possible reason that was given in the interview was that maybe the donor or original hair follicle cells were "out of the growth cycle" when injected in the recipient area. But did they take just one hair follicle and multiply/cultivate that one group of dermal papilla cells, or did they take cells from multiple neighboring follicles, and multiply them all, and then inject the resulting cells into the 1 cm^2 area? What I am getting at is, sure every follicle grows and sheds in cycles, but the follicles that are in the shedding phase on a non-balding person are always surrounded by other follicles, greater in number, that are NOT in a shedding phase, which is why you don't see people "shedding in patches", so to speak. Instead, they shed a few hundred hairs a week, but the shedding hairs are spread out. So if they took a strip of skin with neighboring follicles during the Phase I trials, which is what I think they did, just like they do in today's hair transplant prodecure, and multiplied the entire group of cells, and injected the resulting multiplied cells, you would think that those 2 guys would at least grow back 90% or so of the area, NOT 0%.
I hope I am making sense. =[
So I think that since they grew no hair at all, there is something really wierd going on. Some sort of, I don't know, coordination among neighboring follicles, that decides in the end whether hair will grow, or not. I don't know. I'm just thinking out loud. But hopefully with the design of hte Phase II trials, which will be testing the injected multiplied cells in both an area with no hair at all, and in thinning areas, we will get some answers, even if it is explicitly stated in the interview that the true reason behind HM working or not working is not what they are looking for. They just want to test it to see if it works on a larger scale, and with what process or protocol or specific ingredients.
Baby steps. It is so true. We humans love to take huge leaps, when we should just take one step at a time.
That's what I like about the design of the Phase II trials. I think it will answer a few of these questions.
I mean, for one, it is really interesting that 2 out of those 7 in the Phase I trials did not regrow hair. Let's assume that they did not regrow any hair, which I'm not sure is explicitly stated, but let's assume that. And the possible reason that was given in the interview was that maybe the donor or original hair follicle cells were "out of the growth cycle" when injected in the recipient area. But did they take just one hair follicle and multiply/cultivate that one group of dermal papilla cells, or did they take cells from multiple neighboring follicles, and multiply them all, and then inject the resulting cells into the 1 cm^2 area? What I am getting at is, sure every follicle grows and sheds in cycles, but the follicles that are in the shedding phase on a non-balding person are always surrounded by other follicles, greater in number, that are NOT in a shedding phase, which is why you don't see people "shedding in patches", so to speak. Instead, they shed a few hundred hairs a week, but the shedding hairs are spread out. So if they took a strip of skin with neighboring follicles during the Phase I trials, which is what I think they did, just like they do in today's hair transplant prodecure, and multiplied the entire group of cells, and injected the resulting multiplied cells, you would think that those 2 guys would at least grow back 90% or so of the area, NOT 0%.
I hope I am making sense. =[
So I think that since they grew no hair at all, there is something really wierd going on. Some sort of, I don't know, coordination among neighboring follicles, that decides in the end whether hair will grow, or not. I don't know. I'm just thinking out loud. But hopefully with the design of hte Phase II trials, which will be testing the injected multiplied cells in both an area with no hair at all, and in thinning areas, we will get some answers, even if it is explicitly stated in the interview that the true reason behind HM working or not working is not what they are looking for. They just want to test it to see if it works on a larger scale, and with what process or protocol or specific ingredients.
Baby steps. It is so true. We humans love to take huge leaps, when we should just take one step at a time.
