Different types of DHT

[Petchsky]

Hey Bryan, i've been doing some research and looking up topical anti androgens, what are your thoughts on flutimide? seems to me like it may be more effective than spironolactone...

Also, what do you think about Revivogen?

 

[Bryan]

Hey Bryan, i've been doing some research and looking up topical anti androgens, what are your thoughts on flutimide? seems to me like it may be more effective than spironolactone...

It's okay as a general antiandrogen, but I think it's a lousy topical antiandrogen. That's because there are animal studies showing that it works almost entirely through systemic absorption. There are some anecdotal reports from guys who claim to be using it topically with some success, and I don't know what to make of those claims.

Also, what do you think about Revivogen?

I still consider it to be a big question mark. The extent to which it works (if any) needs to be clearly elucidated by independent researchers. I doubt that will ever happen.

 

[die_hard]

Treeshaw/Diehard

You are both right, i have a new girlfriend and basically freaked out like a newbie when i had problems getting wood, what i needed was a b**ch slap, where were you guys huh? . Easier to blame proscar than the incessant drinking, lack of exercise, drugs etc that has characterised the last few months.

Treeshaw - the earliest photos i have to compare my hair is from 2004, not 2002 unfortunately, but when looking at a photo of my hair now and then it's really hard to tell if i have lost any ground at all, i don't know your regimen but i feel nizoral and min have really helped strengthen and prolong the effects of proscar.

It's good to see you're back on track unk:

 

[Jm0311]

So how would you work in your rogaine and spironolactone if you have Proxiphen? or would you not use it?


Would a Revivogen/Proxiphen combo be worth wild?

 

[Petchsky]

Proxiphen has spironolactone and rogaine in it.

rev and prox would be worth a shot.

 

[$tackz]

don't mistake what bryan's saying though as he is a little tricky with words... he calls flutamide a "lousy" topical anti-androgen because it has little to no local effect, but instead works by being absorbed systematically. this of course says nothing about it's effectiveness, just that it has a higher incidence of side effects which may scare some people. in general users report MUCH success treating male pattern baldness with flutamide. *cue Bryan coming in to say why not just swallow it*

spironolactone get's a bad rap from people simply because it doesn't work. It's been proven to shrink and reduce sebaceous gland size in hamster flanks organs which in theory should correlate with male pattern baldness in humans however that is clearly not the case. in my opinion it just doesn't work and there isn't one success story online with pictures to prove otherwise!

 

[Bryan]

don't mistake what bryan's saying though as he is a little tricky with words... he calls flutamide a "lousy" topical anti-androgen because it has little to no local effect, but instead works by being absorbed systematically. this of course says nothing about it's effectiveness, just that it has a higher incidence of side effects which may scare some people. in general users report MUCH success treating male pattern baldness with flutamide. *cue Bryan coming in to say why not just swallow it*

LOL! You know me pretty well!

spironolactone get's a bad rap from people simply because it doesn't work. It's been proven to shrink and reduce sebaceous gland size in hamster flanks organs which in theory should correlate with male pattern baldness in humans however that is clearly not the case. in my opinion it just doesn't work and there isn't one success story online with pictures to prove otherwise!

Oh, I think it works a little, it's just nothing to write home about. There's the Italian study with topical spironolactone for male pattern baldness, of course, and there's that other study with women only. There's also the paper on topical spironolactone for hairloss that Dr. Proctor described being passed around at the medical conference he attended once. He said the haircount improvements were roughly similar to what you get with Propecia.

 

[SoThatsLife]

Bryan, if spironolactone don't have a effective anti-androgen, what makes Proxiphen so special that you say it is the best treatment without finasteride? I thought every treatment needed a anti-androgen.

Sorry for all my questions, I am just trying to figure out what I should test the next year. If Proxiphen works good I don't think I would have a problem with using 100$ a month on it. But I kinda want to stop finasteride, and if Proxiphen don't have an effective anti-androgen it is pretty much screwed for us mid-20ties that have started to thin rapidly.

 

[Bryan]

Bryan, if spironolactone don't have a effective anti-androgen, what makes Proxiphen so special that you say it is the best treatment without finasteride? I thought every treatment needed a anti-androgen.

One would certainly think so, especially with all this chatter you see on hairloss sites about DHT this, DHT that... But Dr. Proctor is exclusively associated with a very different point of view, one that stresses the importance of what I call those "turbocharged" SODs like PBN and TEMPO/TEMPOL. He seems to think that those are the most effective hairloss fighters of all, and he's the one who's been in this business for decades. I tend to give his judgement a lot of weight.

 

[Jm0311]

I have been on spironolactone for quite awhile......I will keep you posted on what happens.

I dont know anyone else that is currently using this topical anti androgen.

If we can find a topical routine that is very effective, I think that would be a big help to this board.

I am on spironolactone and including Tricomin this week


Thoughts for 09: Revivogen/Proxiphen, or Xandrox 15 Plus/spironolactone

 

[treadstone]

Oh, I think it works a little, it's just nothing to write home about. [...] There's also the paper on topical spironolactone for hairloss that Dr. Proctor described being passed around at the medical conference he attended once. He said the haircount improvements were roughly similar to what you get with Propecia.

Propecia-like regrowth is nothing to write home about?