Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
- Start date
temple regrowth after 3 months of E2 injections, spironolactone (I changed to bicalutamide a couple of weeks ago).
I'm also using finasteride and oral minoxidil, but I'd been on that treatment for over a year with good results before starting hrt.
What amazes me the most is that I don't have recession at the temples, just some very very slight thinning. My main concern is the diffuse thinning at the top; I have shown pictures of my hair before starting HRT, but I won't show them again atm, as there is not much to show yet. But judging by the regrowth at the temples, I hope to see a significant improvement in 3 more months.
I'm also using finasteride and oral minoxidil, but I'd been on that treatment for over a year with good results before starting hrt.
What amazes me the most is that I don't have recession at the temples, just some very very slight thinning. My main concern is the diffuse thinning at the top; I have shown pictures of my hair before starting HRT, but I won't show them again atm, as there is not much to show yet. But judging by the regrowth at the temples, I hope to see a significant improvement in 3 more months.
Attachments
regarding "manhood": My libido is not gone, but very different. I don't get random erections anymore, but if I'm "in the mood" it feels awesome, and works just like before. The only sexual downside I see so far is the lack of sperm.
- Reaction score
- 121
Relax mate, give it a chance to work. You’ll likely loose ground first.. Generally a good sign that the drugs are actually working. Especially with 10mg minoxidil. I lost ground also before I saved my hair.. give the drugs at least 6months to work mate. Don’t let it consume your life mate get out in the sun and enjoy life. No doubt you’ll be happy with your hair in 6month/1year with those drugs. Cheers
Im using oral minoxidil since 1 year. Dutasteride since 5 years and Ive been loosing ground on it.
I went from Norwood 1 to Norwood 4 in 5 years while using Dutasteride...
Only Bicalutamide is a drug that im using since 1 month and Its my last hope
- Reaction score
- 1,206
Spend another 5 years on Dutasteride, Minoxidil and Bica and you won't have any hair at all. The advisors in this thread will tell you to give the drugs more time, 6-12 months, so it's not that far from reality lol.
And you will make this survival bias and you will continue to hope.
Last edited:
- Reaction score
- 1,206
Treating hair loss with HRT, HRT cycles will eventually lead to testicular atrophy and inability to produce your own T, forcing you to either stay on HRT forever or use T injections. I will try testing RU between cycles and see if it will support my baldness. Hope it's not too expensive...
Now I am read information about post-cycle therapy, which is used by bodybuilders after using steroids. According to the information I have, Clomid can help restore T levels and turn on your testicles after a course of estradiol, but each time it will work worse, and eventually, sooner or later, the testicles will die.
So the victims are quite serious, and we need a good drug to support. But if the choice comes between testicles and hair, I will choose the latter and be ready to sacrifice my T for the sake of hair, without which my whole image, my whole appearance is destroyed.
People here think I'm promoting something, but in fact, I always understood that HRT is a remedy for the desperate, who put hair above all else.
Now I am read information about post-cycle therapy, which is used by bodybuilders after using steroids. According to the information I have, Clomid can help restore T levels and turn on your testicles after a course of estradiol, but each time it will work worse, and eventually, sooner or later, the testicles will die.
So the victims are quite serious, and we need a good drug to support. But if the choice comes between testicles and hair, I will choose the latter and be ready to sacrifice my T for the sake of hair, without which my whole image, my whole appearance is destroyed.
People here think I'm promoting something, but in fact, I always understood that HRT is a remedy for the desperate, who put hair above all else.
one anecdotal case like yours doesn't define what others will experience. For many with aggressive baldness bica is more than enough, specially when used with oral minoxidil and of course a 5ar-inhibitor. And yes, 6 months is the least you should give to a treatment before discarding it.
"The medical records of patients who underwent radical prostatectomy with ADT were retrospectively reviewed. In all, 221 patients were included in the analysis. Testosterone recovery was defined as supra-castration (SC) (testosterone levels in serum >50 ng/dL) or out of hypogonadism (OH) (>300 ng/dL) after ADT withdrawal.
Patients treated with ADT for ≤18 months recovered to OH in a mean of 6.8 months (74.6%), but patients treated with ADT for >18 months recovered in a mean of 9.7 months (27.5%)".
www.ncbi.nlm.nih.gov
if you don't abuse hrt (using high doses for more than 18 months) there are good chances that you won't have any problems... the ideal treatment plan is not to use full hrt for more than 12 months; afterwards, with a low dose of bicalutamide + 5ar-inhibition you should be able to maintain the progress you've made; maybe even a really small dose of E2 would solve any health related problems of ADT form bicalutamide.
Patients treated with ADT for ≤18 months recovered to OH in a mean of 6.8 months (74.6%), but patients treated with ADT for >18 months recovered in a mean of 9.7 months (27.5%)".
Factors associated with testosterone recovery after androgen deprivation therapy in patients with prostate cancer - PMC
We investigated factors affecting testosterone recovery after androgen deprivation therapy (ADT) withdrawal in patients with prostate cancer. The medical records of patients who underwent radical prostatectomy with ADT were retrospectively reviewed. ...
www.ncbi.nlm.nih.gov
if you don't abuse hrt (using high doses for more than 18 months) there are good chances that you won't have any problems... the ideal treatment plan is not to use full hrt for more than 12 months; afterwards, with a low dose of bicalutamide + 5ar-inhibition you should be able to maintain the progress you've made; maybe even a really small dose of E2 would solve any health related problems of ADT form bicalutamide.
Last edited:
- Reaction score
- 1,206
Successes in aggressive early baldness will not even fit on the fingers of one hand. Besides, I don't remember him helping anyone without E. Dani was successful, but at what age did his baldness start? Success was with Ein with a rather strange pattern of female pattern baldness, and with DHTcel, which outperformed people on HRT, making it hard for me to believe they are real. In the Russian segment, in this thread where I read all the posts, he helped a minority. You are so focused on successful cases, overlooking those who continued to go bald on Bicalutamide.
No, and if elementary logic is available to you, then you should understand this:
If your baldness, your follicle miniaturization continues after the medicine has accumulated in your body and started to do its job, then there is no point in waiting any longer, the negative dynamics will not change. And to notice the negative dynamics, in my experience, three months are enough. Not changing your treatment regimen for half a year if you see continued deterioration is a big folly.
If the drug works for you, you should at least see no progression of miniaturization after the drug has reached its concentrations. Notice I'm not talking about telogen hair loss.
By the way, I have never experienced telogen shedding.
If Bicalutamide didn't stop hair loss before HRT, it won't stop it after HRT when my T and DHT are back. For example, Dutasteride did not stop Noah's baldness before HRT, and after HRT, remaining on it, he began to go bald again. You seem to have a logic problem.
Last edited:
- Reaction score
- 1,206
too long. In addition, no one argues with the fact that a one-time androgen blockade will not cause problems. But I was going to do cycles of HRT every year, and there is no guarantee that the situation will not worsen.
Bicalutamide does not have the side effects of ADT associated with a decrease in estradiol levels. If you don't know about it, then I don't know what to talk to you about. I suggest you read wikipedia lol
first of all, you don't have aggressive baldness... aggressive baldness means reaching an advanced Norwood (3-4) before your 20's. You have diffuse thinning (and not much tbh).
And the information I'm giving you is not drawn out of my own experience or even anecdotal evidence in a forum. You seem to feel like a scientific or researcher when your IDEAS, because that's what they are, are based on your own experience.
our genetic predisposition to hair thinning due to androgens will only progress in the presence of androgens. I don't understand how you can discard such a powerful AA like bicalutamide, just by the 3 months or whatever period of time you were on it.
There is a reason why you have to give at least 6 months to any treatment to evaluate its performance: The hair cycle. 3 months after starting any treatment you may as well be seeing the thinning from the couple of months before starting, caused by the previous presence of androgens.
my thinning was noticeable when I was 16-17.. and finasteride worked for me (at least for maintenance).
you seem to have many problems, but I'm not going to point them out.. Any reasonable person who reads this thread will be able to notice them.
And the information I'm giving you is not drawn out of my own experience or even anecdotal evidence in a forum. You seem to feel like a scientific or researcher when your IDEAS, because that's what they are, are based on your own experience.
our genetic predisposition to hair thinning due to androgens will only progress in the presence of androgens. I don't understand how you can discard such a powerful AA like bicalutamide, just by the 3 months or whatever period of time you were on it.
There is a reason why you have to give at least 6 months to any treatment to evaluate its performance: The hair cycle. 3 months after starting any treatment you may as well be seeing the thinning from the couple of months before starting, caused by the previous presence of androgens.
my thinning was noticeable when I was 16-17.. and finasteride worked for me (at least for maintenance).
you seem to have many problems, but I'm not going to point them out.. Any reasonable person who reads this thread will be able to notice them.
bicalutamide still is one strongest forms of ADT. Meaning it has side effects like:
- hot flashes
- decrease of libido
- gynecomastia
- insomnia
- testicular atrophy
if you think wikipedia is solid medical literature, I suggest you watch a couple of conferences regarding this drugs. I doubt you will understand anything like uptodate, lancet or even amboss (real medical literature)
- Reaction score
- 1,206
By aggressiveness of baldness, I mean how easy it is to treat. As a rule, the earlier it starts, the more sh*t you find yourself in. My hair loss started accelerating last year, which is when I switched to HRT.
Then I'm waiting for you to study Bicalutamide on young guys < 20 years old, lol
I have not given up on Bicalutamide and have been using it for over a year without a break.
On Bicalutamide, I experienced three miniaturization cycles: one month later, 3 months later, and 5 months on (after 3 months I upped the dosage to 100mg). That was enough. Or now you say that it was necessary to wait a year?
Cool story
Last edited:
- Reaction score
- 1,206
So you think that estradiol can help with these effects that bicalutamide causes?
sure.. insomnia, hot flashes, fatigue / weakness.
and the biggest benefit of adding e2 to a maintenance treatment using bicalutamide is being able to lower the dose of bica. And thus, decreasing the negative effects to the liver.
Of course you would have to either get gyno surgery or not care.
but you are stuck with hrt cycles, so it doesn't matter.
and the biggest benefit of adding e2 to a maintenance treatment using bicalutamide is being able to lower the dose of bica. And thus, decreasing the negative effects to the liver.
Of course you would have to either get gyno surgery or not care.
but you are stuck with hrt cycles, so it doesn't matter.
- Reaction score
- 1,206
I think these effects are usually seen in older people with prostate cancer. The thing is, I haven't heard of anyone experiencing side effects related to weakness, poor sleep, or anything else. Maybe Dani, I don't remember well. The fact is that Bicalutamide does not reduce hormone levels, and side effects such as weakness, drowsiness are usually characteristic of a decrease in hormone levels. For me, this is something from the category of semi-mythical PFS from Finasteride. But to be honest, I'm generally not susceptible to side effects.
This is largely due to the fact that I am not subject to the placebo effect and do not attribute every ailment to the medication. It's also funny when people who reduce the dosage of any drug claim that it immediately relieved them of side effects, but the half-life of their drugs is too long to be able to feel the change in dosages in less than a few weeks.
Of course, I do not deny the possibility of side effects: we react to drugs in different ways. But I always treat claims of side effects such as weakness with a grain of salt, because such a side effect cannot be verified in any way, and it is often caused by the patient's hypochondria, and may be psychosomatic in nature.
I think the negative effects of Bicalutamide on the liver are overrated. If you're fine for half a year, I don't think you have anything to worry about.
I don't see the point of adding small doses of E to Bicalutamide, because in my case it won't stop the hair loss and doesn't eliminate the side effects of E. In short, I get the effects of HRT while continuing to go bald lol. I prefer to either use E fully in HRT, or not use it at all.
Last edited: