Exploring The Hormonal Route. Hair=life.

Sonolmn98

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@Sonolmn98 : I think Dutasteride is stronger than Spironolactone (for hair loss). Spironolactone lost its effectiveness after some time (I just saw another topic on reddit about that today).
I have androgen receptors upregulation. And to counteract it ... I'm trying very high dose estradiol ... Injection 1ml every 5 days (40mg/ml), it's my last hope.
How much estradiol are you taking ? Sublingually ?
8-9 mg a day, I take 2 mg pill every 3-4 hours, iam not saying that spironolactone is effective, it just need to be combined with estrogen and finestride to see results
 

Father_of_Shiseido

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Honestly, I don't think people should take advice from the guy who has a full head of hair yet claims he's a NW6 and says Spironolactone can make you bald. Unless you can explain how it can make you bald with proof.

Do you even know what an NW6 is?
I said that spironolactone would not halt hairloss if used alone. I never said that spironolactone would make you lose more, you idiot.
 

Ikarus

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Guys, not everyone need to be on this extreme protocol, if you are a nw1, then taking finasteride with spironolactone is more than enough to stop the baldness from progressing, a small dose of estradiol may help in regrowth, me and @bridgeburn are taking heavy doses of estrogen and are castrated because we had advanced baldness

I think this will work for 99% of guys
200mg of spironolactone + 5mg finestride+4mg of estradiol

If you are still losing hair in that protocol then you are delusional

I agree, but this is just tea: some people could stop hair loss and regrow their hair. But one day when they're showering, they notice one or two hairs which have shed then go into panic mode thinking they're balding. That is the definition of delusion.
 

Ikarus

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I said that spironolactone would not halt hairloss if it is used alone. I never said that spironolactone would make you lose more, you idiot.

"There are plenty of people who went bald while on spironolactone." If you weren't being literal, you should have expanded further on that.

Anyway, I'm not sure why you're acting so hostile.
 

Marky

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I am taking finasteride, topical estradiol, and oral minoxidil. I will start spironolactone next week. I'm going to have so many drugs on board :(
I know eh. I went from using dutasteride once a week thinking i'm dropping a nuclear bomb in my body. Then bridge comes along and shows what a nuclear bomb drop really is. Or maybe hydrogen bomb in his case.
I thought about using E over a year ago then forgot about it when I read it can cause stroke. But I guess all drugs put down worst case 1 in a million scenarios.
 

itchymadscalp

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8-9 mg a day, I take 2 mg pill every 3-4 hours, iam not saying that spironolactone is effective, it just need to be combined with estrogen and finestride to see results

Omg you're starting strong ! I read it's better you take 2mg at first, and add 2mg every month or 2 months.

You're going to remove the boobs ? or embrace your new femininity ?
 

Marky

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Exactly man. I saw the picture a few pages ago and the hair is ridiculously thick.
@Father_of_Shiseido - You need to start seeing other surgeons and doctors. You are obsessing over hairloss when it is barely evident. The hair is sooo bloody thick, it's laughable that you think you are going to develop Norwood 6 pattern.
it's about what rate it's falling out at. I've known people with thin fine hair but hardly any falls out over a decade, then some with thick fat hair that ends balding.
 

Father_of_Shiseido

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@Sonolmn98 : I think Dutasteride is stronger than Spironolactone (for hair loss). Spironolactone lost its effectiveness after some time (I just saw another topic on reddit about that today).
I have androgen receptors upregulation. And to counteract it ... I'm trying very high dose estradiol ... Injection 1ml every 5 days (40mg/ml), it's my last hope.
How much estradiol are you taking ? Sublingually ?
Can you give me the link to that Reddit thread?
 

Sonolmn98

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Omg you're starting strong ! I read it's better you take 2mg at first, and add 2mg every month or 2 months.

You're going to remove the boobs ? or embrace your new femininity ?
If the boobs get noticeably big over baggy T shirts then I will have them surgically removed (no diy, only real surgeon) a small puffy nipple will not hurt to keep,i think being surgical castrated makes estrogen more effective in the body, I did a recent prostate exams and my prostate has disappeared to nothing, iam taking estrogen because of it is health benefits like neurotransmitters enhancements, anti depressant property... Etc.hair regrowth is a bonus, I tried 2mg but T it wasnt enough to get rid of hot flashes so I upped the dose into 8mg with weeks
 

Father_of_Shiseido

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He's not pervert, because he has (almost) no sex drive. He's pure now :p

I'm sorry but your hair loss is not as bad as you said, I thought you really had almost no hair, and obviously you have plenty of hair. Like @AnxiousAndy , but he has a lot more hair than you, indeed. I won't say you're not balding, but maybe it's not so bad. I hope your regimen will work for you and you won't end having no hair at all on the top of your head.
I have been managing my hair loss since the last 9 years using dutasteride. I have seen how my hair got thinned out over the years. So far spironolactone is not working, notwithstanding it is giving me huge gyno. I am afraid about what will happen to my gyno if I add estradiol at this moment.
 

itchymadscalp

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If the boobs get noticeably big over baggy T shirts then I will have them surgically removed (no diy, only real surgeon) a small puffy nipple will not hurt to keep,i think being surgical castrated makes estrogen more effective in the body, I did a recent prostate exams and my prostate has disappeared to nothing, iam taking estrogen because of it is health benefits like neurotransmitters enhancements, anti depressant property... Etc.hair regrowth is a bonus, I tried 2mg but T it wasnt enough to get rid of hot flashes so I upped the dose into 8mg with weeks

Ok. I hope you will find a good surgeon .... mine was very bad, and the result is awful. I have 2 big holes now ... 2 craters. I hope I can get it corrected. Hair loss destroyed my life, and for nothing. I hope you will get all your hair back.
You have a prescription for estradiol ?
 

Marky

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Well, for one. When I was 17 the internet was not as big as it was today. when I was a kid, I didn't use the internet that much at all, that was before facebook, twitter, instagram, etc. I remember using it to send email but thats about it.. and also I actually remember when VHS was still more popular than DVDs. HairLossTalk.com is kinda old, but I didn't know about it.. I spent most of my time playing outside.

when I noticed my balding It was already a slick bald deep recession,.. It was very suddenly! and we are often taught that it is an inevitable thing and it is assumed that hair once its disappeared it is gone.. I first thought that it must be something in the shampoo, It must be societies fault cause there can't be something wrong with me.. I was a very different person back then and I am a lot smarter now.. To be honest, I was hippie-ish type that thought that natural means healthy. >.< I noticed on every singe shampoo bottle the first ingredient was sodium laurel sulfate, and i googled it and found articles saying that its so bad and dries hair and causes hairloss lol. I thought it ust be true, cause it strips the natural oil on our scalp. So I bought a bunch of sulfate free shampoo.. I also was in denial even though I hated that hairline.. "it must be a mature hairline, its a normal hairline for a man. Not everyone goes bald all the way, surely it can't progress further if i make healthy decisions, etc."

At 18, I went into the military and focused on my training for awhile and getting successful.. My hair was thick and could still be brushed to look decent and hide my hairloss. In many pics I didn't look like I was balding. like this:

View attachment 113128

If the wind blew that was stressful.
I searched on the internet and read about finasteride and min.. which the internet made it sound like those are the only 2 options and the only thing that has any proof..

Now, understand. I was really weird.. I was really religious and from a small town and ignorant.. and I had very conservative views on drugs and also doing anything unnatural was wrong. I even thought the same about trans people and surgeries. probably eunuchs too if i knew about them. Its a fucked mentality but I was like that :( . I thought everything synthetic must be evil and that marijuana was the same as meth and I believed it was morally wrong to take a pain reliever if you have a headache.. I know it sounds stupid and ridiculous >< honestly idk.. I may also have been biased cause my dad spent about half of my childhood in jail or prison because of drugs.. When I think of myself back then It feels like a previous life, rather than just a decade ago.

but I still hated my hairline and started looking into it. I read about PFS, and side effects etc. and finasteride sounded like a hardcore castration drug that will make my dick fall off. And I was young, dumb and full of c*m!! so, considering risk vs reward: My hairline then was already totally unacceptable, I didn't realize there was any possibility of regrowing anything on places that were bare skin.. I even heard doctors say this, that it is impossible to have hair from youth again.. :( Therefore, in my head. I thought its kinda pointless to spend money on a drug and risk my dick and brain fog just to maintain a hair state which I already hate.

But I tried minoxidil a couple times. and i remember once I read something that said turmeric was good against hairloss .. and I rubbed turmeric on my scalp,.. but the orange color was too strong and soaked in .. and everyone at work noticed I had orange my hair and forehead and thought WTF.. So I made up a story that I opened a can of raviolis wrong and the sauce splashed on me ><

then after that I went through a phase where I tried to actually accept it. I took the advice of "Just shave it bro" and decided I should transcend Earthly things and be spiritual like a monk and just let go..

View attachment 113129

Of course, eventually. That approach didn't work for long or make me feel better haha.

I got out of the military. and I had a mid-life crisis kinda. I left and traveled the world for 2 years,backpacker style without working. to have adventure while I was still "young". I focused on my travels as top priority and not on hair, doing as many adventure activities as I could. (skydiving, scuba diving, ice climbing, etc.) And I grew a beard to cope with my hair, thinking that I should enjoy the hair that I actually have ability to grow to the max.. and if I grew it long enough then it would take attention away from my scalp (it didn't). and I wore a straw hat all the time..

I made that my identity.

View attachment 113130

cartoon me:

View attachment 113131


I went into beard phase, haha. I liked all the beard pages on facebook and started sharing stuff like this all the time:

View attachment 113132 View attachment 113133 View attachment 113134

Even then, I knew I cared about the hair on my head a billion times more..

After my trip.. my hair loss got to where I just couldn't hide it. I'd spend hours in the mirror to make it look what decent. I always told myself that if my hairline recedes I'd just shave it into a mohawk and grow the center then rock that style. but it became diffuse all over..

And then online, I happened upon the Swiss Temples regimen that was several years ago.. Which opened my eyes the first time that maybe it is actually possible to regrow hair where it wasn't there before! I couldn't believe it.. I bought into the idea that DHT causes PGD2 which is the actual real cause of hairloss rather than androgens directly, and that if you kill the PGD2, increase PGE2, stimulate progenitor cells, and use wounding.. then that can cause the regrowth.. but have to hit all the right angles at the same time..

View attachment 113139

However, I now realize that, while it is true, PGD2 is bad, its not the only problem.. and Swiss is the only one who seems to have gotten good results from that.. but back then I started researching like crazy everything prostaglandin related... I wanted to discover, some secret. I took tons of supplements,

Green apple peel extract, because procyanidin b2 has an interesting study on it. sulforaphane, supposed to increase 3aHsd which deactivates Dht into something else. vitamin e succinate, in vitro reduced pgd2 and increased pge2. Vitamin D, the active form of Vit d activates the vitamin d receptor. and vitamin d receptor activity is shown to be important in anagen initiation.. taurine, it inhibits tgfb if i remember correctly..

I used stuff from the Swiss Prostanglandin Protocal.,,, Stemoxydine, I took some sulfasalazine, mixed castor oil into DMSO.. exposed scalp to the sun,, for a brief time used some miconazole and minoxidil, lithium chloride topically, I dermarolled for a long time..
I took many things based on this:

View attachment 113140



I experimented for year or two.. with crazy hairloss theories.. But then one day. I found pictures on here.. of people who took more extreme regimens and regrowing hair.. and I learned about cases of transgender women regrowing tons of hair, I had heard of estrogen being good for hair, but when I saw pics of HRT results I realized it is actually really really good! What I thought before was impossible is now possible.. So right after I saw that. as soon as I could, I ordered HRT meds and started taking them...

I was 26 then at the start of hrt, now I'm 28..

So.. that's basically, my story.. and you are absolutely right.. I should have not let it get that far but I didn't have faith. Idk, I feel like an idiot and I don't always understand myself either. but that's why I share my story now, and do what is right now, to help others. and teach the truth.
Was your dad bald? You look like a real trooper in that first pic. Did you have a pic between that one and the others you posted just before HRT?
 

itchymadscalp

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I have been managing my hair loss since the last 9 years using dutasteride. I have seen how my hair got thinned out over the years. So far spironolactone is not working, notwithstanding it is giving me huge gyno. I am afraid about what will happen to my gyno if I add estradiol at this moment.

The best is still cyproterone ... but can be really harmful in a long term use (meningioma). Be careful. And how long have you been on spironolactone ?
 

Sonolmn98

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Ok. I hope you will find a good surgeon .... mine was very bad, and the result is awful. I have 2 big holes now ... 2 craters. I hope I can get it corrected. Hair loss destroyed my life, and for nothing. I hope you will get all your hair back.
You have a prescription for estradiol ?
Hair is coming back slowly but surely, iam shedding small fine hair which is good, and now I have new fuzz of regrowth on my thining spot, it is getting thicker, hopefully I dnt have to add minoxidil, i will give estradiol more time and see, but it's definitely better, yeah and I have prescription for that
 

itchymadscalp

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itchymadscalp

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Hair is coming back slowly but surely, iam shedding small fine hair which is good, and now I have new fuzz of regrowth on my thining spot, it is getting thicker, hopefully I dnt have to add minoxidil, i will give estradiol more time and see, but it's definitely better, yeah and I have prescription for that

Yeah if you can avoid Minoxidil it's better.
On high dose estradiol my skin is a bit dried, it's annoying. How is your skin ?
 

Sonolmn98

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Yeah if you can avoid Minoxidil it's better.
On high dose estradiol my skin is a bit dried, it's annoying. How is your skin ?
Skin is fine, I might add progesterone for the libido/energy issues, my endocrinologist said that it helps
 
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