I think some of you guys don't understand how hair loss due to Androgenic alopecia works. First of all estradiol does not prevent T from binding. The thing that estradiol usually does is rise SHBG so it binds more to androgens an have less biological effects. But not only that, you completly missed the part of ' Androgenic alopecia is not about how much T or DHT you have, but the sensitivity to it' so no, e2 is not the solution for everyone, because:
1 Even with lets say 25 ng/dl T and 5 ng/dl DHT you can still go bald due to extreme androgen sensitivity
2. As i said you can have normal androgens levels but have the oxo androgens very high and they have the same binding affinity as regular T to DHT.
3. Biological women has less androgens receptors, that is why they have less androgenic alopecia not because they have high or low e2. That is why they can fix it with spironolactone.
After all this time on HRT I realized e2 is not a cure at all for very sensitive androgen receptors and you must block the receptors with bica, that is why the only cure is AR degrader like GT.
The only reason I keep going with estradiol is because I have to use less bicalutamide and my LH and FSH does not spike with the use of it, so in the long term i dont f*** up my liver with enormous amounts of bica like 150 daily.
