- Reaction score
- 608
Yet somehow no one else had such an adverse reaction to enanthate. I switched from valerate to enanthate last month and there is 0 difference
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
- Start date
- Reaction score
- 2,105
Guaranteed you got an incelic face structure lmao
- Reaction score
- 608
I would feel very weird insulting and arguing with people half my age. idk how boomers do it
- Reaction score
- 2,105
ugly little goblin hahahahahaha
- Reaction score
- 1,242
You said that HRT with Bicalutamide helps you. There is no reason for this to stop working. I can not believe this.
- Reaction score
- 2,105
XYU has the best hair here, I think I’ll trust him over some Asiancel
- Reaction score
- 1,856
There are lot of sh*t that can get fucked up if you are stressed, like elevation on oxo androgens that you can't even know if they are elevated unless you do a specific blood test that are not available everywhere. Btw those androgens has the same binding affinity as T and DHT. Now that I stopped bica my hair got so bad, like pre hrt, and those androgens could be the culprit. That is the reason why e2 alone or in combination with dutas is not sufficient for everyone, even if don't see differences it does not mean everyone has the same genetic as you.
- Reaction score
- 2,105
Preach
- Reaction score
- 1,242
Now my skin on my face and scalp is oily because I haven’t picked up Bicalutamide from the pharmacy yet, but despite this my hair is not getting any worse.
Interestingly, when taking Bicalutamide on testosterone, I had zero oiliness in the skin of my face and scalp, but at the same time I was rapidly going bald.
I decided to take 37.5mg of Bicalutamide 3 times a week. Tablets 150 mg, divided into 4 parts
Interestingly, when taking Bicalutamide on testosterone, I had zero oiliness in the skin of my face and scalp, but at the same time I was rapidly going bald.
I decided to take 37.5mg of Bicalutamide 3 times a week. Tablets 150 mg, divided into 4 parts
- Reaction score
- 2,105
Women still lose hair with high levels of E2. Stacking bica is the ultimate treatment as it shuts down nearly all binding opportunities at AR. Reducing the ligand load is only one part of the battle.
- Reaction score
- 1,242
Estradiol prevents T from binding to receptors and is a growth stimulator.
I have never seen Bicalutamide help women with hair loss other than one study (as always, studies are a parallel universe)
- Reaction score
- 608
Women stop balding with even just spironolactone so I think bica would work even better for them, it's just never prescribed so we don't have any examples
- Reaction score
- 1,856
I think some of you guys don't understand how hair loss due to Androgenic alopecia works. First of all estradiol does not prevent T from binding. The thing that estradiol usually does is rise SHBG so it binds more to androgens an have less biological effects. But not only that, you completly missed the part of ' Androgenic alopecia is not about how much T or DHT you have, but the sensitivity to it' so no, e2 is not the solution for everyone, because:
1 Even with lets say 25 ng/dl T and 5 ng/dl DHT you can still go bald due to extreme androgen sensitivity
2. As i said you can have normal androgens levels but have the oxo androgens very high and they have the same binding affinity as regular T to DHT.
3. Biological women has less androgens receptors, that is why they have less androgenic alopecia not because they have high or low e2. That is why they can fix it with spironolactone.
After all this time on HRT I realized e2 is not a cure at all for very sensitive androgen receptors and you must block the receptors with bica, that is why the only cure is AR degrader like GT.
The only reason I keep going with estradiol is because I have to use less bicalutamide and my LH and FSH does not spike with the use of it, so in the long term i dont f*** up my liver with enormous amounts of bica like 150 daily.
1 Even with lets say 25 ng/dl T and 5 ng/dl DHT you can still go bald due to extreme androgen sensitivity
2. As i said you can have normal androgens levels but have the oxo androgens very high and they have the same binding affinity as regular T to DHT.
3. Biological women has less androgens receptors, that is why they have less androgenic alopecia not because they have high or low e2. That is why they can fix it with spironolactone.
After all this time on HRT I realized e2 is not a cure at all for very sensitive androgen receptors and you must block the receptors with bica, that is why the only cure is AR degrader like GT.
The only reason I keep going with estradiol is because I have to use less bicalutamide and my LH and FSH does not spike with the use of it, so in the long term i dont f*** up my liver with enormous amounts of bica like 150 daily.
- Reaction score
- 2,105
Spot on
- Reaction score
- 1,856
Yeah as much as I hate it, HRT does not help everyone but a combination of estradiol + AR blocker. I stopped bicalutamide for a month now and my hair is getting fucked so fast and the itchiness is incredibly bad. Not to say if I was sensitive to androgens I'm even more now since bica makes receptor more sensitive, if you stop the bica your androgen will work even more than before. Sadly I will have to keep bica at least 12.5 mg daily till GT or other AR degrader releases....
- Reaction score
- 2,105
- Reaction score
- 1,856
They are protected by bica since they are using it, maybe they are not so sensitive to DHT, that is why almas claims it does nothing. Just lucky ppl whose AR is not that sensitive, but for ppl like me who are really fucked(worsen with age) I must say bica is a godsent till an AR degrader release
I think it's obvious that there's elements to balding that are still non-understood scientifically. I think the idea of androgen sensivity alone is absolute bollocks and racks my brain for hours at a time. EC working for me but EEN not working for me has nothing to do with half life, levels, etc, but similar to androgen sensitivity the ester itself does an improper job of making the hormones work effectively in my body.
all i'm sayying is that if you're failing with een you maaaaay wanna try ec because i was failing with een at a similar dosage that ec made me thrive at. and yes, adding bica did make things better but the ec wasn't too shabby on it's own.