@AnxiousAndy Ethynl Estradiol officially has blood clots listed as a rare but serious side effect.
it is not as easily metabolised by the liver as natural E and stays in the body longer.
back in the day, higher doses were in birth control pills until they discovered that the stuff is stronger than they thought.
It is also no longer reccomended for transitioning.
"EE carries a greater risk of blood clot formation and VTE than does natural estradiol, which is thought to be due to different degrees of hepatic metabolism between the two drugs (see
below).
The original formulations of COCs contained as much as 150 μg EE.
[24] However, it was soon found that EE is associated with incidence of VTE and that the risk is dose-dependent.
[24] Subsequently, the dosage of EE was greatly reduced, and is now generally between 25 and 35 μg,
[24] in some cases less than 20 μg,
[24] and not more than 50 μg.
[25][26][23] These lower dosages have a significantly reduced risk of VTE with no loss of contraceptive effectiveness.
[24] "
it has a bad reputation however, millions of women do take it in birth control pills and are fine and the risk of blood clots is much higher if you are obese or smoke.
maybe some are more sensitive to it and taking it with too much cypro could be an issue since they both take a toll on the liver. There are other complications it can cause too like that guy experienced who Dhtpolice said was popping 3 pills of yasmin a day for awhile. lol..
also,
@Pasbrillantebrunette said she had terrible sides while on diane.
oh and sorry to butt in before rupture could reply.