Exploring The Hormonal Route. Hair=life.

Pls_NW-1

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Isn't aldosterone an antagonist of spironolactone? Resveratrol is a phyto-estrogen, I believe.
Yes, Resveratrol recudes adrenal androgen precursors.

I really am not sure how spironolactone certainly works. From my knowledge it flushs put Aldosterone, it can be found then in the urine.
 

Pls_NW-1

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I am thinking more and more that I will be in need of E.

My hair vanishes more and more. I hope I can get bica regrowth as much as DHTcel got lol.
 

Nimos0651

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I am not certain about this as both work similarly by occupying receptors and sort of tricking the body into thinking it has less T when actually more is circulating. Provera(brand name) which is medroxyprogesterone acetate is an AA of sorts that actually lowers T straightforwardly which makes interpreting testing easier. Some people get better results on bica and some on spironolactone.

In my experience, spironolactone needs to be used more gently and titrated because it can have pretty debilitating sides if used in excess. I used 100 mg and 200 mg and 300 mg and probably 50 mg was all that I should have taken but I was less aware of the concept of titration and shedding a couple of years ago. Some people prefer CPA which is sort of in between MPA and spironolactone in terms of how it works. It seems to block receptors and lower T but it is the most dangerous long-term and not approved for use in the U.S. Some people swear by it though and get it from offshore pharmacies.
I’ve been taking 50mg spironolactone for the last 2 months and haven’t noticed any side effects yet. I agree with you I think 200mg is way too much but someone I think his name was “americanhairline” on this website took 200mg with dutasteride and had amazing results it just took time. I’m going to get bloodwork done again soon and hound them for the results so I can update you guys.
 

Swarleyd

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Yes AmericanHairline takes (took?) 200mg of spironolactone since he though that 100mg after one year wasn’t enough because of a shed
 

Pls_NW-1

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@tato123

Hey, our warrior, how is the fight going on?

I thought about your latest posts... Maybe the rise of the liver enzyms raised due to Metformin + Bicalutamide combo. You mentioned the enzyms (smt about glucose?), which metabolize Met., raised!?

Might there be a co-relation?
 

Jakarta_monas

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Hi, I came and asked again, 3 months on spironolactone, gyno is the only change, because it hasn't been there before, is gyno a good sign for hair growth? How long will it take for me to see results at the 200mg spironolactone? , btw I am NW3 And the sebum on the face is still annoying
 

Swarleyd

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You have to take finasteride and dutasteride when you’re on spironolactone since spironolactone obviously raises DHT levels without 5AR
 

Pls_NW-1

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20210316_072305.jpg


Look at all these vellus hairs, crying for rescue! >_<
 

Pls_NW-1

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You have to take finasteride and dutasteride when you’re on spironolactone since spironolactone obviously raises DHT levels without 5AR
spironolactone is weird... as a SAA it decreases androgens, but at the same time it raises them due to the (weak) AA properties on the AR.
 

Pls_NW-1

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@Itsnoahkennedy and other's who did nuclear treatment and then maintained with AA's and/or 5ARi's...

I still can't understand how you all have got rid of the gyno, so the chest is still in a good shape, but not capable anymore to form breasts...

How!? Is there any surgeon able to perform such a surgery!? Is it physically possible!? Lol!
 

Jakarta_monas

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You have to take finasteride and dutasteride when you’re on spironolactone since spironolactone obviously raises DHT levels without 5AR
There are people out there succeeding with spironolactone 200mg without DHT blockers, btw I just found out that spironolactone increases DHT, is there a link maybe?
 
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