Crush the pill, put it in pure ethanol at a 1% concentration. Do some light needling before applying.
Exploring The Hormonal Route. Hair=life.
- Thread starter bridgeburn
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No, then just take it orally. Topical is just to avoid gyno, which will be inevitable with oral administration.
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A great way to spend several years testing drugs and get a deterioration that will then be difficult to cure even on HRT
Of course these treatments are inferior to HRT. But they are also going to have zero effects on fertility and almost no chance of gyno either.
If someone wants to jump straight into HRT, more power to them. It's just not for everyone. But yes, if you are willing to do HRT, the sooner the better.
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And they will not stop baldness, undermining the mental health of the young man, who had high hopes for them. I went through this. Unfortunately, the only way out is HRT at the first sign of baldness. But I understand that no one will go for it until, like me, I go through a series of mistakes. HRT is something that comes after despair and bitter experience...
But what is needed immediately, not at the end. It's hard to admit to yourself that this is the only way out. I understand it.
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Bicalutamide has the highest number of anecdotal stories of success for finasteride resistant hair loss. Very long half life, topical use is challenging due to systemic build up so I would recommend oral at low dose. Very easy to get and very affordable
Sides like gyno will happen even at low dose over time because of the build up.
For a topical AA without sides, check my groupbuy post in the research section.
Sides like gyno will happen even at low dose over time because of the build up.
For a topical AA without sides, check my groupbuy post in the research section.
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What you call 5AP blockers is normally called 5a reductase (with a R not a P) inhibitors. Bica doesn't "destroy" DHT, it just blocks it at the AR with T. E competes with T production by other mechanism but doesn't "destroy" DHT, just lower its conversion from lower T. Congrats, you clearly have demonstrated your ignorance about hrt protocol in one single post. Please refrain from posting more wrong info, these could be unfortunately used by other people who read this thread and try to learn from it.
As for me, I will simply ignore your posts starting now.
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You voiced what I and everyone here knows and said that I do not understand anything about it.
I see no reason to clarify that DHT falls not because E "destroys" it, but because E decreases T, which is converted into DHT - this is already known to everyone. It seems that I mentioned that DHT does not decrease directly:
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2-3 cases for the entire Internet and cases of treatment of female hair loss, which, according to the only study of Bicalutamide, stops in 40-50% of cases? Yes bro. That's a hell of a lot.
I read many, if not all, studies of Bicalutamide at the beginning of the year and have continually updated this thread with it as monotherapy. So thanks, Cap.
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inhibition of ligand-dependent AR activity alone may not be sufficient as AR can be activated by various cellular factors other than the endogeneous androgens testosterone (T) and dihydrotestosterone (DHT), such as growth factors, kinases, co-activator overexpression. Consequently, blocking the binding of T and DHT to AR with a classical antiandrogen may not be sufficient to have the desired efficacy
So Bicalutamide is not an all-powerful pill that will cause you osteoporosis and make you experience menopausal symptoms. And he won't stop baldness
Estradiol, unlike Bicalutamide, lowers T levels and hence DHT
@recedingyt
US Patent Application for SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF Patent Application (Application #20210024458 issued January 28, 2021) - Justia Patents Search
This invention provides novel 3-amino propanamide selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other 5 hyperandrogenic dermal...
patents.justia.com
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If it's blocked why would you want to destroy it?
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been on dutasteride for 1 year, oral minoxidil for 10 months, and now RU for 1 month
hairline has grown new hairs but i dont know if the density and crown have gotten worse or better
the shed is still the same
when do i say f*** it and do estrogen
hairline has grown new hairs but i dont know if the density and crown have gotten worse or better
the shed is still the same
when do i say f*** it and do estrogen
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I recommend you don't if it's just for hair sake. There are alternative treatments with even better potential than hrt but everyone on this thread is willing to ignore them.
Whenever having boobs and being infertile are acceptable. Just remember that chemical castration with high estrogen isn't a cure and might not even make much of a difference.
Would be nice if you got of your high horse for once.
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what are the alternatives
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He believes that everyone should know about the existence of this thread.
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my dick still works after 1 year of dutasteride. will it die if i start bica or do i stand a chance