Finasteride Inhibits 5ar. In This Case, Testosterone Does Not Turn Into Dihydrotestosterone, But You

[Yar]

[QUOTE = "Ollie, post: 1823838, member: 131941"] В основном это работа 5ar3, которая не блокируется финастеридом. [/ QUOTE]
Финастерид (Проскар, Пропеция) - подавляет типы 2 и 3

 

[Yar]

[QUOTE = "Олли, должность: 1823905, участник: 131941"] Чувак .. это не запрещено. Его 5ar тип 3 функции. Финастерид не получает отличного отрастания, потому что он ингибирует только 60% DHT, и если у вас нет генетически одаренных способностей к сильному росту, вы не получите роста. [/ QUOTE]
5α-RI, которые используются в медицине, включают следующее:

Альфатрадиол (Ell-Cranell Alpha, Пантостин)
Алопеции (Avodart) - ингибирует типы 1, 2 и 3
Эпристерид (Aipuliete, Chuanliu) - ингибирует тип 2
Финастерид (Проскар, Пропеция) - подавляет типы 2 и 3
Пила пальметто экстракт (Permixon) - подавляет типы 1 и 2

 

[Yar]

Dude.. its not inhibited . Its a 5ar type 3 function. finasteride doesn't get excellent regrowth because it only inhibits 60% DHT and if you're not genetically gifted in regards to having strong growth pathways then you're not gonna get growth.

not therefore, but because 5AR is inhibited through which progesterone passes which is not metabolized to hydroxyprogesterone, inhibits the effect of DHT and is completely inhibited by 5AR. 5 ar does not need to be inhibited!

 

[baba_yaga]

Dude.. its not inhibited . Its a 5ar type 3 function. finasteride doesn't get excellent regrowth because it only inhibits 60% DHT and if you're not genetically gifted in regards to having strong growth pathways then you're not gonna get growth.

Some people's regrowth is likely to be caused by the elevation of E levels.

 

[Yar]

Some people's regrowth is likely to be caused by the elevation of E levels.

I support, therefore, there are no gorgeous results on finasteride, 5AR is inhibited, which means that another metabolite will not pass through 5AR to its derivative. Progesterone is hydroxyprogesterone.

 

[Manochoice]

Still more alive than me.

Man, no offense here but you may need some other kind of help if the hair is a make or break issue in life. Don't get me wrong, I understand pretty well the esthetics role of hair but let's not get crazy. Of course it also depend on your age. The younger you are, the more difficult to cope.

 

[baba_yaga]

Man, no offense here but you may need some other kind of help if the hair is a make or break issue in life. Don't get me wrong, I understand pretty well the esthetics role of hair but let's not get crazy. Of course it also depend on your age. The younger you are, the more difficult to cope.

Balding at 18 is a death sentence to confidence, self esteem and social life. Life in general will never be the same.
Desperate situations require desperate actions.

 

[Yar]

[QUOTE = "petersonKj, post: 1824045, member: 140197"] это логически фигня. Он дал бы хорошие результаты отрастания. но это не так. он также ингибирует фермент типа 1, который также присутствует в клетках волосяной фолликулы. Тип 1 является наиболее важным и чаще всего встречается в тканях мозга. [/ QUOTE]

this is logically bullshit. IF it would inhibit all types of ar then it WOULD give good regrowth results. but it doesn't. dutasteride more so because it also inhibits the type one enzyme which is also present in the hair follicle cells. type 1 is the most important and its mostly found in brain tissue

other metabolites pass through 5par, not only testosterone to dihydrotestosterone. It does not need to be inhibited !!! Testosterone must be inhibited, not 5par.

 

[whatevr]

[QUOTE = "petersonKj, post: 1824045, member: 140197"] это логически фигня. Он дал бы хорошие результаты отрастания. но это не так. он также ингибирует фермент типа 1, который также присутствует в клетках волосяной фолликулы. Тип 1 является наиболее важным и чаще всего встречается в тканях мозга. [/ QUOTE]

other metabolites pass through 5par, not only testosterone to dihydrotestosterone. It does not need to be inhibited !!! Testosterone must be inhibited, not 5par.

Yes but it is not possible to inhibit only T->DHT conversion without touching 5-AR and f*****g up everything else too. The only way you could do is by using something like Equol which supposedly binds to DHT and renders it inactive, but you would need large doses, 20-30 mg per day, and it is also an estrogen receptor beta stimulant.

And if you use something that lowers testosterone then you also lose estrogen so I don't see how that is much better. Topical androgen receptor antagonist would be an ideal solution, but RU58841 isn't strong enough, and the other ones that were tried (enzalutamide and darolutamide) also performed pathetically and no one had any results.

 

[mannyFJ]

Man, no offense here but you may need some other kind of help if the hair is a make or break issue in life. Don't get me wrong, I understand pretty well the esthetics role of hair but let's not get crazy. Of course it also depend on your age. The younger you are, the more difficult to cope.

I notice you offer no useful info and not even on any regime. Dude do you even have a life outside of this forum?

 

[mannyFJ]

Finasteride inhibits 5AR. In this case, testosterone does not turn into dihydrotestosterone, but you deprive yourself of other metabolic hormones that pass through 5AP. They are also very necessary for the body and hair! For example, a progestin metabolite that is formed from progesterone.

It doesn't totally inhibit...does it?

 

[Manochoice]

I notice you offer no useful info and not even on any regime. Dude do you even have a life outside of this forum?

as it is such and also as such is it unto you it's good man, don't bother with me. I don't get sucked into web toxicity.

 

[mannyFJ]

as it is such and also as such is it unto you it's good man, don't bother with me. I don't get sucked into web toxicity.

Don’t bother others and you wont get banned again

 

[Manochoice]

Don’t bother others and you wont get banned again

Again? )

 

[I'mme]

Yes but it is not possible to inhibit only T->DHT conversion without touching 5-AR and f*****g up everything else too. The only way you could do is by using something like Equol which supposedly binds to DHT and renders it inactive, but you would need large doses, 20-30 mg per day, and it is also an estrogen receptor beta stimulant.

And if you use something that lowers testosterone then you also lose estrogen so I don't see how that is much better. Topical androgen receptor antagonist would be an ideal solution, but RU58841 isn't strong enough, and the other ones that were tried (enzalutamide and darolutamide) also performed pathetically and no one had any results.

Agree but I think topical bicalutamide wasn't given enough chances by folks here. They just wanted to try "the most powerful" anti-androgen topically, perceiving that they won't get any side and that their AR in the scalp would Rip for rest of the life making them cured OF Androgenetic Alopecia.