I am a man of abstraction, and I can't stand to see all these fragmentation everywhere, this is why I am going to create a new thread for each presentation/interview for members to discuss. This is the first one we have and will be adding some for Dr. Lauster's team.
Short Interview between Desmond and Dr. Cotsarelis:
1) Follica's phase 2 trial completed recently with promising results. But they have insufficient funds to continue with further trials. So at this point everything has been put on hold.
2) When I asked him if the rumours were true that the company that conducted the trials on behalf of Follica was found to falsify data and is being sued. He laughed and denied any such matters. So the data they collected is definitely valid I suppose.
3) I brought up the crowdfunding idea particularly with regards to Follica and he said the amount necessary is quite large. So I insisted on an actual amount and here's what he said: "US $2 million would bring out a product that would be more effective than Minoxidil and Propecia but would not give a bald person a full head of hair. US $20 million will provide the kind of funding necessary to give someone who is already bald a full head of hair but it will take more years to accomplish".
4) Also he did say that a full blown cure using Follica's method for an already bald person is still many years away.
5) Regarding the PGD2 approach and the current blockers that are in trials, i mentioned how they are failing to show much benefit in Asthma and trials are being stopped one at a time he seemed very optimistic and believed that is a great thing for hair because companies in general try to keep the number of trials to the minimum. The more trials you do the greater the chances for an adverse effect to be found. He believes that is the best thing that could have happened and may finally give these companies enough willpower to start a trial in hair regeneration.
6) And finally I brought up fgf9 and its potentials. He believes fgf9 is still a very new discovery with many years of preclinical research ahead of it, when I asked for an estimated date he said at least 10 years. He then went on to mention that just to go from Rogaine liquid to Rogaine foam it took the company over 8 years of studies and data collection before they were allowed to sell it and Minoxidil has been on the market for many years. Now imagine if we are trying to bring out a completely new agent. The timeframes are quite long indeed.
Here is the video that Desmond has presented:
https://www.youtube.com/watch?v=TN5H01HGaVI
Wounding Theory with and Practice(updated):
[video=youtube;m84cOOc8-T0]https://www.youtube.com/watch?v=m84cOOc8-T0[/video]
Note: It seems that we can only embed 1 video per post, hmm annoying.
Short Interview between Desmond and Dr. Cotsarelis:
1) Follica's phase 2 trial completed recently with promising results. But they have insufficient funds to continue with further trials. So at this point everything has been put on hold.
2) When I asked him if the rumours were true that the company that conducted the trials on behalf of Follica was found to falsify data and is being sued. He laughed and denied any such matters. So the data they collected is definitely valid I suppose.
3) I brought up the crowdfunding idea particularly with regards to Follica and he said the amount necessary is quite large. So I insisted on an actual amount and here's what he said: "US $2 million would bring out a product that would be more effective than Minoxidil and Propecia but would not give a bald person a full head of hair. US $20 million will provide the kind of funding necessary to give someone who is already bald a full head of hair but it will take more years to accomplish".
4) Also he did say that a full blown cure using Follica's method for an already bald person is still many years away.
5) Regarding the PGD2 approach and the current blockers that are in trials, i mentioned how they are failing to show much benefit in Asthma and trials are being stopped one at a time he seemed very optimistic and believed that is a great thing for hair because companies in general try to keep the number of trials to the minimum. The more trials you do the greater the chances for an adverse effect to be found. He believes that is the best thing that could have happened and may finally give these companies enough willpower to start a trial in hair regeneration.
6) And finally I brought up fgf9 and its potentials. He believes fgf9 is still a very new discovery with many years of preclinical research ahead of it, when I asked for an estimated date he said at least 10 years. He then went on to mention that just to go from Rogaine liquid to Rogaine foam it took the company over 8 years of studies and data collection before they were allowed to sell it and Minoxidil has been on the market for many years. Now imagine if we are trying to bring out a completely new agent. The timeframes are quite long indeed.
Here is the video that Desmond has presented:
https://www.youtube.com/watch?v=TN5H01HGaVI
Wounding Theory with and Practice(updated):
[video=youtube;m84cOOc8-T0]https://www.youtube.com/watch?v=m84cOOc8-T0[/video]
Note: It seems that we can only embed 1 video per post, hmm annoying.
