Goodbye To Baldness .. New Technology Gives You Hope A Team Of Japanese Researchers Has Succeeded In

[That Guy]

Just out of curiosity, on which Norwood scale are you now

2. Slightly worse off than 2, but not enough to be a 3. Had diffuse thinning though, but I caught it early enough that the diffuse isn't an issue anymore.

Are you optimistic generally?

Not even f*****g close lol

He's kind of right to be optimistic about those studies,

Yes.

 

[Hate da Bt]

highly recommend you read the article in sciencedaily. it seems fukuda et al. were able to accomplish tsujis hurdle, that is, large scale production of viable follicle germs. i dont see why this method cant be replicated with human hfgs, which fukuda alluded to has been accomplished already:

"This simple method is very robust and promising. We hope that this technique will improve human hair regenerative therapy to treat hair loss such as androgenic alopecia," adds Fukuda. "In fact, we have preliminary data that suggests human HFG formation using human keratinocytes and dermal papilla cells."

https://www.sciencedaily.com/releases/2018/02/180201142853.htm

Fukuda used embryonic stem cells, which are a lot easier to amplify.
You are wrong.

 

[sadila]

Yes.

you're a bit too optimistic for a nw2, if i were you i wouldn't give a f*** about new treatments for the next 10 years

 

[kingjohn]

Fukuda used embryonic stem cells, which are a lot easier to amplify.
You are wrong.

when did i say that he didnt...? i just said he was able to make hfgs on a large scale, something tsuji is still (as far as we know) trying to accomplish. i never said how he did that...

 

[Hate da Bt]

when did i say that he didnt...? i just said he was able to make hfgs on a large scale, something tsuji is still (as far as we know) trying to accomplish. i never said how he did that...

Repetition is the mother of learning.
Fukuda used primarily murine embryonic stem cells, that are easier to amplify, whereas Tsuji uses murine and human adult stem cells, that are more difficult to amplify on great scale.
In other words, it's easier to create 5,000 germs with embryonic epithelial and mesenchymal cells than with adult epithelial and mesenchymal cells.
I hope I have come across this time, even though the third one is the charm.

 

[That Guy]

you're a bit too optimistic for a nw2, if i were you i wouldn't give a f*** about new treatments for the next 10 years

Doesn't make any sense. I think it would be more optimistic for like, a NW7.

I only want/need something that is a superior option to a transplant, and we will have that by the end of this decade (if we're lucky) or early next. Follica would be able to provide the Dhurat study's results at worst and it is on its last phases. Depending on what they wind up charging for RIKEN or how much regrowth Shiseido can give, those could also be possible options in the next few years.

But 10 years doesn't make any sense based on where these companies are at now. It would be a small-scale cataclysm for them to take that long at this point

 

[Saulus]

Do you think they will cure

Doesn't make any sense. I think it would be more optimistic for like, a NW7.

I only want/need something that is a superior option to a transplant, and we will have that by the end of this decade (if we're lucky) or early next. Follica would be able to provide the Dhurat study's results at worst and it is on its last phases. Depending on what they wind up charging for RIKEN or how much regrowth Shiseido can give, those could also be possible options in the next few years.

But 10 years doesn't make any sense based on where these companies are at now. It would be a small-scale cataclysm for them to take that long at this point

I think if there havent even been human trials 10 years is more than realistic, if not optimistic

 

[That Guy]

Do you think they will cure



I think if there havent even been human trials 10 years is more than realistic, if not optimistic

Except there have been for 2 out of 3 of those, will be one for the other next year and could possibly go to market the year after that given the laws.

I'm not sure where you've been.

 

[kingjohn]

Repetition is the mother of learning.
Fukuda used primarily murine embryonic stem cells, that are easier to amplify, whereas Tsuji uses murine and human adult stem cells, that are more difficult to amplify on great scale.
In other words, it's easier to create 5,000 germs with embryonic epithelial and mesenchymal cells than with adult epithelial and mesenchymal cells.
I hope I have come across this time, even though the third one is the charm.

yet again youre arguing a point i never made, go reread my original post. i simply stated that fukuda et al have accomplished a feat that tsuji et al have not accomplished, that is, the large scale production of hfgs, be that human or murine. never did i specify that fukuda improved tsujis method or even used the same cell lines/types of cells at all... has tsuji et al published a study mass producing hfgs on a large scale, human or murine? NO, thus my original statement stands 100% accurately. feels like were splitting hairs here, pun intended

 

[Hate da Bt]

yet again youre arguing a point i never made, go reread my original post. i simply stated that fukuda et al have accomplished a feat that tsuji et al have not accomplished, that is, the large scale production of hfgs, be that human or murine. never did i specify that fukuda improved tsujis method or even used the same cell lines/types of cells at all... has tsuji et al published a study mass producing hfgs on a large scale, human or murine? NO, thus my original statement stands 100% accurately. feels like were splitting hairs here, pun intended

Dude,
A) The cells were embryonic. Tsuji works with adult cells.
B) Embryonic stem cells can be more easily amplified.
Therefore, the two are almost irrelevant.
Fukuda did NOT overcome the hurdle Tsuji and his colleagues are trying to overcome in their Kobe lab. PERIOD.
Your statement is 100% inaccurate.
Own it and move on.

 

[shookwun]

If I hear mice one more time

 

[Longway886]

Ten pages of pointless arguing to follow

 

[sadila]

I only want/need something that is a superior option to a transplant, and we will have that by the end of this decade

Not sure how you consider on average 8% of hair regrowth (shiseido) superior to a transplant but okay. That's what the studies have provided til now so don't already jump to conclusions. and yes i know phase II is focused on efficacy, but shoudn't we wait for their results to judge if it's superior to a hair transplant ?

Doesn't make any sense. I think it would be more optimistic for like, a NW7.

a nw7 would be more desperate for a new treatment than a nw2, hence why i said you have an inflated optimism for a nw2

 

[Hate da Bt]

Not sure how you consider on average 8% of hair regrowth (shiseido) superior to a transplant but okay. That's what the studies have provided til now so don't already jump to conclusions


a nw7 would be more desperate for a new treatment than a nw2, hence why i said you have an inflated optimism for a nw2

RCH-01 may be a great tool for maintenance and that's exactly what nw2 and 3 need along with a hair transplant.
Without maintenance, a nw2 can't opt for a hair transplant lightheartedly, beboo (edit).

 

[sadila]

RCH-01 may be a great tool for maintenance and that's exactly what nw2 and 3 need along with a hair transplant.
Without maintenance, a nw2 can't opt for a hair transplant lightheartedly, amigo.

Okay booboo

 

[cubsnation_]

So lads, is this it? Do you guys really think that 5 years from now we will have the cure for everyone?

 

[shookwun]

So lads, is this it? Do you guys really think that 5 years from now we will have the cure for everyone?

my suggestion is to stop wasting your time, and have a hair transplant already.

Cant take back time. youth goes quick

 

[razzmatazz91]

my suggestion is to stop wasting your time, and have a hair transplant already.

Cant take back time. youth goes quick

Would love to, but for some of us here it isn't even an option.

 

[hanginginthewire]

He's kind of right to be optimistic about those studies, especially when you read what they've been able to do til now and what they're claiming they can do in the future. One day it's going to be a reality, but that day is still far away, sure we'll maybe get shiseido this year but don't expect 1st gen gene hairloss treatments to be closely effective to what our idea of a cure is.

I’m a diffuse thinner. Patterned. I just want to know when the nightmare is over.

The things people say on here confuse me. Why should I be optimistic for something that’s far away and won’t work well apparently?

It seems like no one knows what the (near to near-ish) future will bring, which is fine. Or it is what it is. But then you have guys basically saying it’s in the bag. 2018! 2019! We’re gonna make it brahs!

I guess a hair loss forum isn’t the National Academey of Sciences and I shouldn’t put stock in anything here, yay or nay. I just want so much to have a clear light at the end of the tunnel.

Not sure how you consider on average 8% of hair regrowth (shiseido) superior to a transplant but okay. That's what the studies have provided til now so don't already jump to conclusions. and yes i know phase II is focused on efficacy, but shoudn't we wait for their results to judge if it's superior to a hair transplant ?


a nw7 would be more desperate for a new treatment than a nw2, hence why i said you have an inflated optimism for a nw2

sadila I thought you agreed the studies justify optimism?

 

[sadila]

sadila I thought you agreed the studies justify optimism?

I still agree. The train has left the station and a cure is on the way sooner or later, but where i don't agree is when people expect a full reversal cure to be out there in the next two years, or when people expect a cure to reach full scale market only after phase II trials in japan, which is not possible. Anyone who says it is haven't read the pmd act in japan, or did not understand what this act is intended for in the first place.