Most likely because of high estrogens:
https://www.ncbi.nlm.nih.gov/m/pubmed/429508/
And why do the very fit lose their hair? If diet and exercise had a perceptible, beneficial effect on hair loss, there would be no balding professional athletes (Roony, James, Brady, etc.). Brady is an excellent example - that guy is obsessive about his diet, and yet he still thinned until he had a transplant and probably finasteride.
I would say you didnt make a big damage. It does increase testosterone but a little and after long term..One of the worst supplement offenders that I've ever used is Vitamin D. Speeds up my hair loss dramatically. I remember there was a member here claiming he regained 5 years of hair loss with Vitamin D supplementation and advising everyone to take it. I have never thinned so fast as when taking 4000-6000 IU of Vitamin D regardless if I take the other cofactors (A, E, K, magnesium, etc.) with it or not. I'll prefer to just get it from the sunlight as much as I can, and if I'm still deficient, then f*** it. Doesn't seem worth it to me.
Yes, thats the point.You support his point, rather than disprove it. Someone being very lean and athletic would have as little estrogen as possible and most likely more androgens. Someone obese will have suppressed testosterone and more estradiol due to increased aromatase activity in fat cells, and we know how protective estrogen is for male pattern baldness hair.
Yes, thats the point.
Of course, as it is transparent from your own words, it is not something i would suggest in order to keep someone's hair (to become obese)
But the estrogenic spyke is enormous so..obese has more aromatase but in the fat, be obese is associated with insulin resistence which lowers Shbg and increase free androgens
Not really. It's true that fat contains aromatase enzyme, thus one would conclude that an obese person would have higher Estrogen than a skinny person. However, obesity is also associated with low SHBG, which would translate to higher free Androgens (T/DHT), thus, knowing that Androgens are stronger than Estrogens, T/DHT would just cancel E in various tissues.But the estrogenic spyke is enormous so..
From wiki : Orally, EE is on the order of 100 times as potent by weight as natural estrogens like micronized estradiol and conjugated estrogens, which is largely due to substantially greater resistance to first-pass metabolism.[72][73][74] It is specifically in the range of 80 to 200 times as potent as estropipate (piperazine estrone sulfate), which has similar potency to micronized estradiol, in terms of systemic estrogenic potency.[75][76] In contrast, the potencies of EE and natural estrogens are similar when they are administered intravenously, due to the bypassing of first-pass metabolism.[36]Relative to its prodrug mestranol, EE is about 1.7 times as potent by weight orally.[73]Where does the study shows that ehinyl estradiol is raising SHBG higher than if using other forms of bioidentical estradiol?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782930/Not really. It's true that fat contains aromatase enzyme, thus one would conclude that an obese person would have higher Estrogen than a skinny person. However, obesity is also associated with low SHBG, which would translate to higher free Androgens (T/DHT), thus, knowing that Androgens are stronger than Estrogens, T/DHT would just cancel E in various tissues.
From wiki : Orally, EE is on the order of 100 times as potent by weight as natural estrogens like micronized estradiol and conjugated estrogens, which is largely due to substantially greater resistance to first-pass metabolism.[72][73][74] It is specifically in the range of 80 to 200 times as potent as estropipate (piperazine estrone sulfate), which has similar potency to micronized estradiol, in terms of systemic estrogenic potency.[75][76] In contrast, the potencies of EE and natural estrogens are similar when they are administered intravenously, due to the bypassing of first-pass metabolism.[36]Relative to its prodrug mestranol, EE is about 1.7 times as potent by weight orally.[73]
Thus, one would conclude that EE is far stronger than E in its effects on the liver. One of the reasons why EE is avoided, because it can cause high chances of VDT.
https://www.ncbi.nlm.nih.gov/m/pubmed/6403446/Thanks. I wonder if taking EE sublingual or bucal can diminish the side-effect on the liver
When taking Estradiol, going the sublingual or bucal route bypasses the first pass metabolism so I also wonder if this provides a way to offset the chances of getting dangerous sides with EE.
https://www.ncbi.nlm.nih.gov/m/pubmed/6403446/
Judging by this study, it appears that EE taken sublingually would lead to higher bioavailability, while retaining its liver-changing properties.
Same here. I really don’t understand it.One of the worst supplement offenders that I've ever used is Vitamin D. Speeds up my hair loss dramatically. I remember there was a member here claiming he regained 5 years of hair loss with Vitamin D supplementation and advising everyone to take it. I have never thinned so fast as when taking 4000-6000 IU of Vitamin D regardless if I take the other cofactors (A, E, K, magnesium, etc.) with it or not. I'll prefer to just get it from the sunlight as much as I can, and if I'm still deficient, then f*** it. Doesn't seem worth it to me.