Hair loss reversed in alopecia areata sufferers

[mr the hairy monkey]

Fresh from BBC : http://www.bbc.com/news/health-28834058

 

[Armando Jose]

Also comments in this post
http://www.hairlosstalk.com/interac...-hair-within-5-months-in-majority-of-patients

 

[mr the hairy monkey]

Also comments in this post
http://www.hairlosstalk.com/interac...-hair-within-5-months-in-majority-of-patients

oops , I haven't seen that , thank you for letting me know Armando Jose

 

[EvilLocks]

I should be happy that AA sufferers may have a cure on the rise, but all I can think is that if they find a cure to AA I'll be even more alone as a balding girl than before. It'll not be a cure for Androgenetic Alopecia, since the mechanisms behind AA and Androgenetic Alopecia hair loss are totally different. With AA the follicles are never miniaturized, dormant or lost; it's just an autoimmune condition which treats hair as foreign. If they can find out how to stop the body from attacking follicles, they will have a cure. Maybe this will be the cure. But with Androgenetic Alopecia you are battling something completely different; genetics. AA is a disease, Androgenetic Alopecia is not (although it should be one). You can cure a disease, but cure genetics? A world of difference. The only difference this will make for us is watching other people get their hair back. And let's not try to be sweet and kind here, we all know we want OUR hair back.

 

[Anarch]

Soon, friend. I hope we're all cured soon enough. :wave:

I should be happy that AA sufferers may have a cure on the rise, but all I can think is that if they find a cure to AA I'll be even more alone as a balding girl than before. It'll not be a cure for Androgenetic Alopecia, since the mechanisms behind AA and Androgenetic Alopecia hair loss are totally different. With AA the follicles are never miniaturized, dormant or lost; it's just an autoimmune condition which treats hair as foreign. If they can find out how to stop the body from attacking follicles, they will have a cure. Maybe this will be the cure. But with Androgenetic Alopecia you are battling something completely different; genetics. AA is a disease, Androgenetic Alopecia is not (although it should be one). You can cure a disease, but cure genetics? A world of difference. The only difference this will make for us is watching other people get their hair back. And let's not try to be sweet and kind here, we all know we want OUR hair back.

 

[bushbush]

I should be happy that AA sufferers may have a cure on the rise, but all I can think is that if they find a cure to AA I'll be even more alone as a balding girl than before. It'll not be a cure for Androgenetic Alopecia, since the mechanisms behind AA and Androgenetic Alopecia hair loss are totally different. With AA the follicles are never miniaturized, dormant or lost; it's just an autoimmune condition which treats hair as foreign. If they can find out how to stop the body from attacking follicles, they will have a cure. Maybe this will be the cure. But with Androgenetic Alopecia you are battling something completely different; genetics. AA is a disease, Androgenetic Alopecia is not (although it should be one). You can cure a disease, but cure genetics? A world of difference. The only difference this will make for us is watching other people get their hair back. And let's not try to be sweet and kind here, we all know we want OUR hair back.

Why are you so confident that genetics play no role in AA?

"it's just an autoimmune condition which treats hair as foreign" - this does not mean that it is not under genetic influence.

Wikipedia:

Alopecia areata is not contagious.[SUP][2][/SUP] It occurs more frequently in people who have affected family members, suggesting heredity may be a factor.[SUP][2][/SUP] Strong evidence of genetic association with increased risk for AA was found by studying families with two or more affected members. This study identified at least four regions in the genome that are likely to contain these genes.[SUP][11][/SUP] In addition, it is slightly more likely to occur in people who have relatives with autoimmune diseases.

"AA is a disease, Androgenetic Alopecia is not (although it should be one). You can cure a disease, but cure genetics? A world of difference." - Check your definition of a disease. Genetic diseases exist.

 

[dps]

there is hope guys, there are stories of a guy who suffers from GENETIC alopecia good ole male pattern baldness, and he took one of those arthritis drugs NOT FOR TREATING male pattern baldness... and as a side effect he got his hairline back.
ask hellouser.

 

[mr the hairy monkey]

I just hope that this sort of treatments won't be life-time ones ,as is the case for Androgenetic Alopecia .... when it comes to bilking people out of their money , industry is a genius.
if it's only 5 months followed by nothing , that would suit everybody , well except maybe for the company that sells it.

Androgenetic Alopecia is a bigger fish though.

 

[hellouser]

I just hope that this sort of treatments won't be life-time ones ,as is the case for Androgenetic Alopecia .... when it comes to bilking people out of their money , industry is a genius.
if it's only 5 months followed by nothing , that would suit everybody , well except maybe for the company that sells it.

Androgenetic Alopecia is a bigger fish though.

There will be no shortage of people that will take it... 7 billion is the world's population, ever increasing and replenishing of the old geezers that die out.

 

[EvilLocks]

Why are you so confident that genetics play no role in AA?

"it's just an autoimmune condition which treats hair as foreign" - this does not mean that it is not under genetic influence.

Wikipedia:

Alopecia areata is not contagious.[SUP][2][/SUP] It occurs more frequently in people who have affected family members, suggesting heredity may be a factor.[SUP][2][/SUP] Strong evidence of genetic association with increased risk for AA was found by studying families with two or more affected members. This study identified at least four regions in the genome that are likely to contain these genes.[SUP][11][/SUP] In addition, it is slightly more likely to occur in people who have relatives with autoimmune diseases.

"AA is a disease, Androgenetic Alopecia is not (although it should be one). You can cure a disease, but cure genetics? A world of difference." - Check your definition of a disease. Genetic diseases exist.

Yeah sure but you must agree with me that theoretically, it should be easier curing a disease that does not destroy the follicles, than a condition (or disease, doesn't matter what you call it really) that permanently destroys/compromises the follicles? In AA there are healthy follicles but they will not grow hair as the body treats it as a foreign. In Androgenetic Alopecia The follicles are progressively and permanently damaged. I'm surprised there isnt a cure for AA yet as the problem seems to be how to make the body stop attacking hair so the healthy follicles can start working again. In Androgenetic Alopecia we need to find a way to reverse those dormant follicles and make them larger again, ultimately starting to produce hair. This article even says that it will not likely work in Androgenetic Alopecia as it's mostly hormonal/genetics. If you wanna be optimistic sure, but it's most likely not gonna do anything... If they do find a cure i will be extatic tho.

 

[hellouser]

Yeah sure but you must agree with me that theoretically, it should be easier curing a disease that does not destroy the follicles, than a condition (or disease, doesn't matter what you call it really) that permanently destroys/compromises the follicles? In AA there are healthy follicles but they will not grow hair as the body treats it as a foreign. In Androgenetic Alopecia The follicles are progressively and permanently damaged. I'm surprised there isnt a cure for AA yet as the problem seems to be how to make the body stop attacking hair so the healthy follicles can start working again. In Androgenetic Alopecia we need to find a way to reverse those dormant follicles and make them larger again, ultimately starting to produce hair. This article even says that it will not likely work in Androgenetic Alopecia as it's mostly hormonal/genetics. If you wanna be optimistic sure, but it's most likely not gonna do anything... If they do find a cure i will be extatic tho.

Follicles are never destroyed in Androgenetic Alopecia either. Cotsarelis confirmed this at the World Hair Congress that Desmond attended. It's on video as well and clearly states the presence of cells in slick bald areas.

Also, take the article's writer's comments with a fine grain of salt. Most of the people in media that write about hair loss, well actually damn near all of them, know jack sh*t about alopecia and come to ridiculous conclusions. There's NO evidence of ruxolitinib not being able to work on Androgenetic Alopecia and therefor any comments on this are pure speculation. These kind of premature comments and negative assumptions do more harm than good. Ie; sulfasalazine has been known to revert hair loss (as evidence by my link to the Hair Loss Help thread) and yet little to no research has been done on it at all.

 

[Muzzle]

We dont have much time for a cure for Androgenetic Alopecia baldness, i think there is no meaning getting full head of hair after 35

 

[hellouser]

We dont have much time for a cure for Androgenetic Alopecia baldness, i think there is no meaning getting full head of hair after 35

You'll care when your 35 or 85.

 

[EvilLocks]

Follicles are never destroyed in Androgenetic Alopecia either. Cotsarelis confirmed this at the World Hair Congress that Desmond attended. It's on video as well and clearly states the presence of cells in slick bald areas.

Also, take the article's writer's comments with a fine grain of salt. Most of the people in media that write about hair loss, well actually damn near all of them, know jack sh*t about alopecia and come to ridiculous conclusions. There's NO evidence of ruxolitinib not being able to work on Androgenetic Alopecia and therefor any comments on this are pure speculation. These kind of premature comments and negative assumptions do more harm than good. Ie; sulfasalazine has been known to revert hair loss (as evidence by my link to the Hair Loss Help thread) and yet little to no research has been done on it at all.

Sure but they are compromised, even you can't say otherwise. I like that there are still people like you who gives a glimmer of hope (something we all need) but I'm really one of the negative ones... Then if there is a cure they can give me a happy surprise.

You are right it hasn't been tested on Androgenetic Alopecia but in reality Androgenetic Alopecia and AA are completely different.

None of you can argue that theoretically it seems easier to make an already healthy follicle (AA) grow hair again, than sparking a compromised and small (miniaturized) follicle to reverse itself to normal state, THEN produce hair again.

 

[Python]

Sure but they are compromised, even you can't say otherwise. I like that there are still people like you who gives a glimmer of hope (something we all need) but I'm really one of the negative ones... Then if there is a cure they can give me a happy surprise.

You are right it hasn't been tested on Androgenetic Alopecia but in reality Androgenetic Alopecia and AA are completely different.

None of you can argue that theoretically it seems easier to make an already healthy follicle (AA) grow hair again, than sparking a compromised and small (miniaturized) follicle to reverse itself to normal state, THEN produce hair again.

There is one maybe two cases on forums where drugs for different things like for arthritis have been used and they got their hair back with Androgenetic Alopecia. And just recently those drugs also regrew hair on AA according to a Yale study. So it points to a glimmer of hope. I am currently trying one of them out, otherwise we will need know.

 

[mr the hairy monkey]

We dont have much time for a cure for Androgenetic Alopecia baldness, i think there is no meaning getting full head of hair after 35

depends on what kind of person you are talking about.

if you are an actor or a celebrity you'll need you hair even when you'll be in your casket.

if you are some farmer that lives away from society you wouldn't be much concerned about your appearance , even if you were a zoophile , your cows won't give a rip about your hair....

 

[I.D WALKER]

Considering that hair loss adds maybe 10 years (+/-) to our looks I'm thoroughly convinced that even many middle agers are longing to restore some of their stolen youth. When you think about this more I would go as far to opine they may yearn for hair help just as much if not more in order to help compensate for the depreciating appearance that naturally comes with age.

 

[shivers20]

You'll care when your 35 or 85.

This.

I thought that at the age of thirty six I wouldnt care as much as in my early twenties. I was WRONG, **** still bothers me the same.

 

[Mr White]

[...] It'll not be a cure for Androgenetic Alopecia, since the mechanisms behind AA and Androgenetic Alopecia hair loss are totally different. With AA the follicles are never miniaturized, dormant or lost; it's just an autoimmune condition which treats hair as foreign. [...]

Yes but it's definitely great news for AA sufferers. And who knows, maybe this new discovery can somehow help to develop a new Androgenetic Alopecia treatment, too - even though they're different conditions, like you said.

By the way, has anyone tried ruxolitinib for male pattern baldness?

 

[hellouser]

Sure but they are compromised, even you can't say otherwise. I like that there are still people like you who gives a glimmer of hope (something we all need) but I'm really one of the negative ones... Then if there is a cure they can give me a happy surprise.

You are right it hasn't been tested on Androgenetic Alopecia but in reality Androgenetic Alopecia and AA are completely different.

None of you can argue that theoretically it seems easier to make an already healthy follicle (AA) grow hair again, than sparking a compromised and small (miniaturized) follicle to reverse itself to normal state, THEN produce hair again.

There's only one sure way to find out if it will work or not:

TRIAL.

Sitting around and bitching whether it will or won't doesn't do any of us any good. Someone needs to try it out, orally or topically. NOW.