Hair Multiplication Update:Histogen!

tonyj

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Hmmm, It's been available in the U.S. since 2009. Dermaheal is a little cheaper at Amazon.com and Regrowth has a 15% discount coupon for the Dermaheal product. Since I have free shipping with Amazon, I might go for the shampoo.
 

waynakyo

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tonyj said:
Hmmm, It's been available in the U.S. since 2009. Dermaheal is a little cheaper at Amazon.com and Regrowth has a 15% discount coupon for the Dermaheal product. Since I have free shipping with Amazon, I might go for the shampoo.

Can you please show us the link showing it is available ... no one mentioned that on the other forum..

and what was the link with Dermaheal ?
 

tonyj

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waynakyo,

I searched google and this is what I came up with. I wanted to know more about Renokin so I looked into the company. The company that developed Renokin is called Caregen. This is a biotech company that opened in 2001. The CEO is Yongji Chung, PH.D in Molecular Biology. He is a proponent of something called the Mesotherapy (I don't know what mesotherapy is all about) which was developed by Dr.Michel Pistor back in 1952.

If you take a look at the South Korea yellow pages, there is some info on Caregen.

http://www.southkoreapages.com/company/caregen.php

If you compare that to Dermaheal's website the about us section, you'll see that they reference a company in South Korea started in 2001 by a Ph.D in molecular biology.

http://dermahealproducts.com/about-dermaheal-products

You can find dermaheal's products on Amazon.com
http://www.amazon.com/DermaHeal-Dermahe ... B002JQ3KEG

Just spotted a thread at the Hairloss Fight forum discussing the Dermaheal LA Science as I was writing. The info should be useful.

http://www.hairlossfight.com/forums/vie ... php?t=1130

Sorry about that, apparently the server won't let me display the link on "The Other Forum," so you 'll have to do your search their.
 

somone uk

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it's a snake oil and idk why it's on this thread :eek:fftopic: :eek:fftopic:

they seem relatively modest about their results but the results non the less seem fabricated
a study is nothing without a peer review

and products that are marketed as a cosmetic rather than a medicine usually don't have medicinal advantages but rather cosmetic advantages
in other words i think it mearly works like a thickening shampoo
anyway i am using minoxidil and finasteride and it's frankly hm or nothing as far as i am concerned now
 

tonyj

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Yes, you are correct of course, just a little of side track.

Back to Histogen, there is some inconsistencies in way the proof of concept image was presented on this thread, the control area of the head was on the right side, but on this document in the link below, the control is on the left side. I don't know which would be correct.

http://glamsolutions.com/wp-content/upl ... 8.6.10.pdf

Update- If the proof of concept image on the link has the correct side of the control area, this would explain the bald spot on the front left side on the mans head.
 

tonyj

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Is there any news on Histogen's topical pilot trails in the U.S. They were to have two trials? both trails were on transplanted hair to see if the topical could prevent hair loss.
 

andrei_eremenko

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latest updates!

Histogen Announces Completion of Series A Financing

SAN DIEGO, December 1, 2010 - Histogen, Inc., a regenerative medicine company developing solutions based on the products of newborn cells grown under embryonic conditions, today announced the successful completion of its Series A financing at $10 million. Among other private investors, Secure Medical, Leonard Lavin, Lordship Ventures and Angus Mitchell brought the round to a close.

With its pilot clinical trial for hair regrowth completed, a skincare line launched, and exciting preclinical data in applications including oncology, Histogen has added significant value which was recognized by the Company's new and existing shareholders. In addition, Histogen has recently moved into a new facility that will allow for up-scaled manufacturing for its upcoming clinical trials, and later commercial production.

"With the Series A completed, we are excited to build on the momentum Histogen has created over the past two years, and further advance the Company's rich product portfolio," said Gail K. Naughton, Ph.D., CEO and Chairman of the Board for Histogen. "We have made significant strides in several important research areas, advanced partnership discussions, and are on track to reach key value inflection points in 2011."

This successful completion follows the announcement of initial Series A financing in May 2008. Simultaneously, Histogen opens its Series B financing, which has been approved up to $23 million. The Series B was opened by Angus Mitchell, and Histogen has already received further commitments toward that round.

The Company is scheduled to begin a Phase I/II clinical trial of its Hair Stimulating Complex (HSC) in Singapore in Spring 2011, and hopes to also begin a clinical study of its soluble human extracellular matrix (hECM) for the treatment of carcinomatosis, a rapidly progressing and debilitating cancer, mid-year.
 

person

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Excellent (Mr Burns style lol).
 

person

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Can someone please explain to me what histogen actually is? I listened to the bald truth programme and essentially they are injecting their magic formula and after 7 months the hair starts to go crappy again; so basically you would need an injection every 7 months? And what does it actually do in those 7 months? Does it sort of wash away the DHT temporarily? I'm quite confused by Histogen :) .
 

malo

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person said:
Can someone please explain to me what histogen actually is? I listened to the bald truth programme and essentially they are injecting their magic formula and after 7 months the hair starts to go crappy again; so basically you would need an injection every 7 months? And what does it actually do in those 7 months? Does it sort of wash away the DHT temporarily? I'm quite confused by Histogen :) .


I think you are confusing Histogen with PRP (platelet rich plasma)
Histogen has gone thru a phase 1 pre-trial and is scheduled to begin
a phase 1/2 trial in singapore in 2011.
In its phase 1 trial it proved that it continued to grow hair a year after its
initial application.
 

Letac

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I think you are confusing Histogen with PRP (platelet rich plasma)
Histogen has gone thru a phase 1 pre-trial and is scheduled to begin
a phase 1/2 trial in singapore in 2011.
In its phase 1 trial it proved that it continued to grow hair a year after its
initial application.[/quote]

Is it some kind of lubricant you put on to your scalp, or is it some kind of injection as well? I heard that Matristem is some kind of thing that makes the donor-area grow back (if it will work)...

Are there any pictures of these trials on the web? And are there any dates/year that this prosess will be finished - or they think that they might have something to release on the market?

I`m kinda new here, so sorry for all the questions!:)

I`m not sure if this is the right page to be asking this question, but if any of these trials acctualy will be great sucess, will one person have unlimited supply of donor-hair so that you can get a thick and full head of hair again? I know that it`s a bit early to be dreaming of again, but a person do have hope:)
 

malo

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Is it some kind of lubricant you put on to your scalp, or is it some kind of injection as well? I heard that Matristem is some kind of thing that makes the donor-area grow back (if it will work)...

Are there any pictures of these trials on the web? And are there any dates/year that this prosess will be finished - or they think that they might have something to release on the market?
I`m kinda new here, so sorry for all the questions!:)
I`m not sure if this is the right page to be asking this question, but if any of these trials acctualy will be great sucess, will one person have unlimited supply of donor-hair so that you can get a thick and full head of hair again? I know that it`s a bit early to be dreaming of again, but a person do have hope:)

Histogen is a growth factor using WNT proteins it is not available yet
The company is entering into phase 1 and 2 trials this coming year.
It gets injected into the scalp. If you look on their website you can see
some photos and explanation of the therapy and early results.
The earliest this might be available is 2013/14 in certain Asian
countries, And then possibly 2015 in America.

Acell is a product that has been used for wound healing.
In the past five or six years some hair transplant doctors have
been studying various ways to use it in hair transplantation.
(faster healing and growth)

Recently a well respected hair restoration doctor by the name of Jerry Cooley
began experimenting with it to see if he could use it to auto-clone new hair.
In his experiment he plucks a hair from the donor area with more of the
underlying cell intact. He then coats the plucked hair with the acell solution
and implants it into the balding area. In theory the plucked hair re-grows and the transplanted hair grows as well. He has had early success with this but
there is still a great deal of research that needs to be done.
There are also two other highly respected transplant surgeons starting to study this.
They are Dr. Robert Bernstein and William Rassman.
The advantage of Acell if it works is that there will be an unlimited amount of donor hair and no chance of disfiguring scars in the donor area (back and sides of the head)
We should know more about it efficacy by this time next year

I am not a medical professional so this is my lay persons explanation of these procedures. I hope this helps.
 

person

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malo said:
Is it some kind of lubricant you put on to your scalp, or is it some kind of injection as well? I heard that Matristem is some kind of thing that makes the donor-area grow back (if it will work)...

Are there any pictures of these trials on the web? And are there any dates/year that this prosess will be finished - or they think that they might have something to release on the market?
I`m kinda new here, so sorry for all the questions!:)
I`m not sure if this is the right page to be asking this question, but if any of these trials acctualy will be great sucess, will one person have unlimited supply of donor-hair so that you can get a thick and full head of hair again? I know that it`s a bit early to be dreaming of again, but a person do have hope:)

Histogen is a growth factor using WNT proteins it is not available yet
The company is entering into phase 1 and 2 trials this coming year.
It gets injected into the scalp. If you look on their website you can see
some photos and explanation of the therapy and early results.
The earliest this might be available is 2013/14 in certain Asian
countries, And then possibly 2015 in America.

Acell is a product that has been used for wound healing.
In the past five or six years some hair transplant doctors have
been studying various ways to use it in hair transplantation.
(faster healing and growth)

Recently a well respected hair restoration doctor by the name of Jerry Cooley
began experimenting with it to see if he could use it to auto-clone new hair.
In his experiment he plucks a hair from the donor area with more of the
underlying cell intact. He then coats the plucked hair with the acell solution
and implants it into the balding area. In theory the plucked hair re-grows and the transplanted hair grows as well. He has had early success with this but
there is still a great deal of research that needs to be done.
There are also two other highly respected transplant surgeons starting to study this.
They are Dr. Robert Bernstein and William Rassman.
The advantage of Acell if it works is that there will be an unlimited amount of donor hair and no chance of disfiguring scars in the donor area (back and sides of the head)
We should know more about it efficacy by this time next year

I am not a medical professional so this is my lay persons explanation of these procedures. I hope this helps.

Yeah it does help; which do you think has more chance of success acell or histogen? Also when I said the hair loses integrity after 7 months they said that in a histogen interview on the bald truth but perhaps I was wrong.
Do you think that the autocloned hairs will be DHT resistent? Surely they will if the acell solution is regrowing the dht sensitive follicle which was plucked? :dunno:
 

malo

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Yeah it does help; which do you think has more chance of success acell or histogen? Also when I said the hair loses integrity after 7 months they said that in a histogen interview on the bald truth but perhaps I was wrong.
Do you think that the autocloned hairs will be DHT resistent? Surely they will if the acell solution is regrowing the dht sensitive follicle which was plucked? :dunno:

Acell is available to doctors now so I would think that there will be answers and results sooner. As I said in my earlier post Dr. Bernstein and Rassman are starting studies with it in their practices as we speak. So this is a good thing. Both these men are giants in the field of hair restoration and they are skeptical of therapies that are new and unproven so I am cautiously optimistic about Acell. I don't think Acell will ever bring back our 16 year old hair but it could be a big advancement in hair restoration surgery. So I think by this time next year we will know if the hair is DHT resistant and about its ability to cycle more than once.

As for Histogen I have never read that it loses its integrity after 7 months that sounds like PRP (platelet rich plasma) which is an injection of stem cells culled from your own blood. I had this done about a year ago and the benefits were temporary.

In fact if you read about Histogens results they said there was continued growth after one injection, one year later. If Histogen is successful it would be a huge advancement in hair loss prevention. There is an interview with Gail Naughton the CEO of Histogen in which she states that the hair re-grown from the hair stimulating complex will last as long as it did before it was lost. So in theory if hair did not start to fall out until you were say 28 years old it should last that long again. Well that's what she says anyway. I hope it is true.

Histogen is a fairly small company so money is crucial to them They just got another ten million in funding so that means that some investors have faith in them. Which in my opinion is good. I am sure if more investors got on board they could speed things up but it hasn't happened yet.

i have no inside information but these are some of the points that have been brought up on other forums. There is a great deal of excitement about these therapies so people become passionate and over zealous about them and sometimes this leads to the wrong interpretation of what was originally said. So it helps if you go to the blogs and websites of the doctors and companies directly involved with the therapies.

Again, I hope this helps.
 

Letac

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What do you guys think about the Histogen product? After my opniniom I think that they are the most exciting out there at the moment. After some mail correspondance with them I have the impression that they fully believe that can change the whole market when it comes to hair etc. They will start their next trials early 2011 up to mid 2011. They will have results after 3, 6, 9 and 12 months. The pictures they posted on the website was with only a few injections (dunno how many). The next trials will be with a lot more, so that means that the really expect great results within the next year. If this will come true....man, I cant even say how gratefull I will become!:)

This is gonna be a really exciting year when it comes to hair and some kind of cure. What do you guys think?
 

malo

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dudemon said:
Letac said:
What do you guys think about the Histogen product? After my opniniom I think that they are the most exciting out there at the moment. After some mail correspondance with them I have the impression that they fully believe that can change the whole market when it comes to hair etc. They will start their next trials early 2011 up to mid 2011. They will have results after 3, 6, 9 and 12 months. The pictures they posted on the website was with only a few injections (dunno how many). The next trials will be with a lot more, so that means that the really expect great results within the next year. If this will come true....man, I cant even say how gratefull I will become!:)

This is gonna be a really exciting year when it comes to hair and some kind of cure. What do you guys think?

Aderans supposedly has a "release date" of 2014, for their product to become commercially available. They also are apparently conducting phase II this year (2011).

But I wouldn't hold your breath on it. To me, it just sounds like more of the same old "it's just 3 to 5 years away" BS :jackit: that we've been told for the last 15 to 20 years.

Then there's the fact that Bosely is funding Aderans as far as I know .... which is bad news because anything Bosely puts their slimy hands on instantly turns to $hit.

dudemon I always respect your posts but I think you have it backwards.
Bosley does not fund Aderans. It's the other way around Aderans bought Bosley. Aderans is one of the largest Wig manufactures in Japan. I think now they call themselves Uni-hair and are basically trying to get involved in everything having
to do with hair. At least they have the capital to throw at the research. So we can only hope.
 

person

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I still don't understand Histogen; it doesn't seem to address the problem of DHT. If I have to compare it to anything would minoxidil be a good analogy? Does it simply boost the hair but not stop it going bald later? I'm confused.
 

malo

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person said:
I still don't understand Histogen; it doesn't seem to address the problem of DHT. If I have to compare it to anything would minoxidil be a good analogy? Does it simply boost the hair but not stop it going bald later? I'm confused.


No you're right is doesn't address DHT but if it works the way Gail Naughton
(CEO of Histogen) implies then if you regrow hair that you didn't lose until you were
in your twenties it should last that long again. (in theory) still if you can regrow hair and use Propecia to maintain that would be pretty good.
Lets keep our fingers crossed.
 

Ende

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And a company called Histogen has a hair growth stimulant in the works that is being held up by a lawsuit.
http://theweek.com/article/index/210507 ... e-baldness
Histogen’s entire future depends on a ruling from a South California federal judge. The company was sued by SkinMedica, claiming that Histogen CEO Gail Naughton is using SkinMedica’s trade secrets. SkinMedica bought a drug called NouriCel from Advanced Tissue Sciences, the suit claims. Naughton was the founder of ATS. When she left the company to create Histogen she hired people who had trade secret knowledge of SkinMedica’s newly acquired property, the suit alleges.

When the suit was filed, Histogen’s investors panicked and pulled their funding. Xconomy:

The patent suit, which was filed a year ago by Carlsbad, CA-based SkinMedica, hit just as Histogen was preparing to report early results of its experimental treatment to stimulate hair regrowth among 24 men with male-pattern baldness. (...) the prospect of costly litigation prompted a group of angel investors to withdraw their planned $2.4 million investment, and Histogen was forced to lay off all 36 employees.

If Histogen can find funding — and if it prevails in court — the company plans a larger trial of HSC in Singapore.
http://www.bnet.com/blog/drug-business/ ... gling/3973
 
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