HMI-115 PRLR antibody: The Most Promising Treatment Ever

[HMI 115 IS THE CURE dude]

Something else that I find interesting is that a similar PRLR mA is being used to treat prostrate cancer . many of the best drugs that treat prostate cancer also work for male pattern baldness

“Based on preclinical data, combination therapy of LFA102 with those novel agents targeting hormonal pathways in metastatic castration-resistant prostate cancer and metastatic breast cancer is promising.”

 

[pegasus2]

Something else that I find interesting is that a similar PRLR mA is being used to treat prostrate cancer . many of the best drugs that treat prostate cancer also work for male pattern baldness

“Based on preclinical data, combination therapy of LFA102 with those novel agents targeting hormonal pathways in metastatic castration-resistant prostate cancer and metastatic breast cancer is promising.”

Not only that, but acne too. Metabolic syndrome is also associated with Androgenetic Alopecia, and I'm sure you know about all the old men regrowing their hair on RA drug benoxaprofen before it was quickly banned.

 

[RolfLeeBuckler]

They don't need the money. Don't do this. They have more than enough to conduct the phase 2.

I'm sure they are. There are lots of NW3-5 diffuse thinners. They aren't going to accept people with no temple loss at all.

I am sorry i don’t understand your answer.

i asked you whether you think of Hope Medicine Will do trials with diffuse hair loss people… and you answered „Yes they Are“

could you please Tell me what you have meant?

 

[Flamingflaps]

I am sorry i don’t understand your answer.

i asked you whether you think of Hope Medicine Will do trials with diffuse hair loss people… and you answered „Yes they Are“

could you please Tell me what you have meant?

I think his point was that if they do trials on the more typical Norwood patterns, some of those people will also have diffuse thinning. If you’ve got a Norwood 4, there’s also going to be diffuse thinning throughout the scalp. But doing a trial on someone with full coverage but a little sparse throughout - they couldn’t guarantee that it’s AA.

either way, if it works on the typical patterns why wouldn’t it work on diffuse patterns?

 

[RoryGall29]

If everything goes well when all the 3 Clinical Trials will be completed? 2026?

 

[RStGeorge]

The role of high Prolactin levels in Androgenetic Alopecia

 

[1919]

Thank you so much for the very thorough analysis pegasus! Wish you were one of the guys in the lab, then maybe the 5-year curse might become history by now .
Anyways, I haven't been online for a while, so Im wondering if Bayer is currently the only known company pursuing the prolactin receptor angle.

 

[RolfLeeBuckler]

I think his point was that if they do trials on the more typical Norwood patterns, some of those people will also have diffuse thinning. If you’ve got a Norwood 4, there’s also going to be diffuse thinning throughout the scalp. But doing a trial on someone with full coverage but a little sparse throughout - they couldn’t guarantee that it’s AA.

either way, if it works on the typical patterns why wouldn’t it work on diffuse patterns?

I Want to Go into Phase II trials with diffuse pattern

 

[Jackshtbro]

I Want to Go into Phase II trials with diffuse pattern

You're outta luck buddy

 

[pegasus2]

That article overlooks that prolactin has a direct effect on HFSCs, that HF produces its own prolactin independent of the pituitary gland and serum prolactin levels, and that catagen is initiated by a reduction in Wnt signaling and that loss of blood flow comes afterwards as a result of catagen not a cause. When Wnt signaling is restored the HF enters anagen again and blood flow is restored.

 

[pegasus2]

Thank you so much for the very thorough analysis pegasus! Wish you were one of the guys in the lab, then maybe the 5-year curse might become history by now .
Anyways, I haven't been online for a while, so Im wondering if Bayer is currently the only known company pursuing the prolactin receptor angle.

For hair loss they are the only one

 

[RolfLeeBuckler]

too bad (that they wouldnt accept me) I'm a Norwood 1 but HEAVY diffuse thinner ... my hairlooks looks like female hair-loos almost

Anyway, watch this guy's 1 year old opinion on the subject

You don’t know If they would accept you right? You Are just speculating Right?

 

[Jackshtbro]

You don’t know If they would accept you right? You Are just speculating Right?

It's over rolf

 

[RolfLeeBuckler]

It's over rolf

You Are a son of a b**ch.

 

[Nostro300]

You don’t know If they would accept you right? You Are just speculating Right?

are you in Australia, because only australian residents of a certain area are allowed to register to the trial so nevermind if you only have diffuse thinning

 

[RolfLeeBuckler]

are you in Australia, because only australian residents of a certain area are allowed to register to the trial so nevermind if you only have diffuse thinning

No i am Not in Australia But i Hope that they will do Phase II trials in US and EU soon to participate in

 

[waynakyo]

How come there is no group buy on this yet?

 

[Exodia]

How come there is no group buy on this yet?

It’s only being sold to research institutions. Even if we had a research institution buy it for us it would be too expensive.

 

[RStGeorge]

It’s only being sold to research institutions. Even if we had a research institution buy it for us it would be too expensive.

Maybe you can ask Professor Sinclair, who frequents the http://reddit.com/r/hairlossresearch sub on his monthly Q&As. He is running the trial in Melbourne

 

[RagnarLothbrok]

Yeah, how much could it cost for our "research institution"? (we can maybe pull one up)

If there isn't production problems why wouldn't they want more people willing to test it who finance it themselves.