How does finasteride (or duta) stop working? (or be less effective?)

[telogen]

The unfortunate part of AAs . We cant win boys. I imagine the loss will be ridiculous after upregulating your ARs so much and then dropping the AA. You think cycling different AAs will do anything? Or since they all do the same thing it wont matter

I've tried to switch daily between using RU and Oh-Flut, but i don't think it helps in regards of counteracting upregulation.

Staying away from using AR antagonists for some time (couple of months) definitely helps, the issue is exposing your hairline and temples for harmfull T when off-cycle which will do damage. I'm now trying topical Estriol (20mg x2 ed) as an replacement for RU/Oh-flut when cycling off AR antagonists, and it does help on the itch which usually appears on the hairline when not using RU/Oh-flut. Only time will tell if it's potent enought to maintain for 2-3 months before going back on RU/Oh-flut.

 

[crikey1980]

You might be right about RU58841 Upping the AR regulation but how do you explain MPMD success with the drug and many others anecdotal success.
Cycling RU58841 makes zero sense to me, you either take it or don't.

 

[Equal Rights]

You might be right about RU58841 Upping the AR regulation but how do you explain MPMD success with the drug and many others anecdotal success.
Cycling RU58841 makes zero sense to me, you either take it or don't.

You take it for a long period of time it upregulates AR, you increase the dosage to make it effective again, overtime it upregulates AR even more. Its a never ending cycle. That is why people that have been using it for years say that theyve always had to continuously up the dosage. Letting your ARs recover may be the way to do it. But then you lose most gains within a couple of months.

 

[Abomination]

You might be right about RU58841 Upping the AR regulation but how do you explain MPMD success with the drug and many others anecdotal success.
Cycling RU58841 makes zero sense to me, you either take it or don't.

I've read myself some success story of continued RU usage with no increased baldness, at least so far. Honestly I have no idea. Perhaps it's genetic, some people's receptors upregulate and some don't, who the f*ck knows really.