Norwood One
Experienced Member
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- 139
How much better are things looking now compared to 10 years ago?
- Thread starter INT
- Start date
Optimistic we will see an actual new treatment cross the finish line in the next 5 years or so. That being said im with others like swoop that its going to be something like CB that is similar to finasteride or rogain. A little regrowth, but a cure is just fantasy for the coming decades. Your looking at more of the same and a little progress I think. Better ways to keep hair and maybe more regrowth along the lines of rogain certainly not huge amounts of hair.
It depends on what we see as a cure. Personally something that would work as good as dutasteride with zero side effects would already be a cure.
farkhairloss
Established Member
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- 37
If Replicel really ends up immunising hair follicles against DHT, we have reached a cure for those above NW3. This single treatment will completely revolutionise the hairloss industry! hair transplant surgeons would roll in cash as everyones trying to recreate their juvenile hairline after immunising their hair against DHT! At least 50% of hair loss sufferers will try to do something about their hairloss as there's finally a permanent solution available.
Samumed may face regulatory scrutiny during their approval process, since playing with WNT signalling is quite dangerous indeed. I'd be surprised if it gets approved in the timeframe they are forecasting.
Histogen has definitely given us some hope. Lets hope Mexico will happen. I personally know trial patients who had minor regrowth & maintained their Norwood for over 14 months after a single session!
Latanoprost will simply be an alternative to Minoxidil.
Tsuji, Lauster & Xu are still a good 5-10 years away from having a commercial product available on the market.
All in all though, Shiseido trial results will be very interesting to find out. The theory is solid. Lets hope it pans out in a real life human patient
Great to have you back on the forums Desmond. Again thanks for the email reply and looking forward to news of what your working on.
big_head
Established Member
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Can someone explain the reality of dutasteride to me? I have some questions:
1. You can't get it for hair with a legit script, correct? Only online as it is only prescribed for prostate?
2. Do most people see the kind of amazing results I hear about? I hear about aggressive regrowth at only 4-5 doses of .5 mg a week.
3. Are the sides just as aggressive? Why doesn't everyone take dutasteride?
Sorry for hijacking this, but dutasteride seems to be the closest overall thing to a "cure"- just as good as finasteride at stopping baldness, but way more regrowth.
1. You can't get it for hair with a legit script, correct? Only online as it is only prescribed for prostate?
2. Do most people see the kind of amazing results I hear about? I hear about aggressive regrowth at only 4-5 doses of .5 mg a week.
3. Are the sides just as aggressive? Why doesn't everyone take dutasteride?
Sorry for hijacking this, but dutasteride seems to be the closest overall thing to a "cure"- just as good as finasteride at stopping baldness, but way more regrowth.
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1. You can buy it from online pharmacies without a script, just do a script with their "online doctor" (fill out a few questions)
2. Not everybody. It's no doubt the best treatment for male pattern baldness though, with the highest potential for regrowth.
3. Because quite simply, its a seriously powerful drug. Only a small minority of hairloss sufferers are comfortable taking finasteride, let alone dutasteride. It inhibits 5AR1 which plays no role in male pattern baldness and affects neurosteroids, and inhibits a further 30% or so serum DHT compared to finasteride. It also has a half life of months, compared to finasteride's half life of hours, meaning if you do get nasty sides, they may persist for a long time after stopping the drug. It has less long term safety studies than finasteride and is not an approved hairloss medication.
big_head
Established Member
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- 51
So it's obviously smarter to give finasteride a go before even thinking about dutasteride...it does sound scary. All the paranoia around finasteride sounds better suited for dutasteride.
Have you ever tried it?
- Reaction score
- 331
Histogen and Replicel are the two new possible upcoming treatments I've been looking up to the most. I could probably restore my original Norwood 1 if they turn out to be excellent treatments and most likely won't need a hair transplant if they're that effective.
big_head
Established Member
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- 51
I keep hearing conflicting things about Histogen though. Did anyone get a clear answer about their "Faked" results pictures? I hope it's not just minoxidil 2.0.
From what I understand Histogen is a collection of harvested growth factors, even if it works and you get regrowth what is there to stop those hairs from eventually being attacked too? If PGD2 antagonists do prove halt hair loss, a combination of Histogen and Seti may be something that works, we will have to wait and see.
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Yeah I wonder what the long-term benefits of histogen will be, if any.
But if it comes out in 2017 or 2018, I'm likely to try it. Hopefully it's not $15,000.
But if it comes out in 2017 or 2018, I'm likely to try it. Hopefully it's not $15,000.
Giiizmo
Established Member
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- 148
Wishful thinking: Androgenetic Alopecia is a chronic disease which stems from an imbalance between different inflammatory mediators (prostaglandins) and keeps on going once it is initiated. Imagine if Histogen managed to reverse the tide, thus stopping the balding process dead in its tracks for a few months/years until it is triggered again, allowing for both regrowth and maintenance.
Hey, why not? Desmond reported a test subject who maintained is hairline and had a small amount of regrowth over 14 months after only one injection. One can dream.
Hey, why not? Desmond reported a test subject who maintained is hairline and had a small amount of regrowth over 14 months after only one injection. One can dream.
I don't think Histogen can reverse the underlying causes of Androgenetic Alopecia as it is a just growth factors at the end of the day. However I don't see any reason why it would not cause regrowth with enough dosage and distributed injections.
If they can make the production a industrial process and lower the price so that you can go for additional "top-ups" once a year that may also be a better business model.
If they can make the production a industrial process and lower the price so that you can go for additional "top-ups" once a year that may also be a better business model.
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- 1,332
Hmm..
How do you explain that some people don't have any inflammation going for them? Why do some show miniaturization without any indications of inflammation?
- Reaction score
- 200
As far what the future holds, it's a little better. 10 years ago was 2006. Correct me if i'm wrong, but people were still kinda talking about the same thing. Stem cell research was passed in 2008, 8 years ago. Really not that much of a difference imo. Everything is still 5-10 years away like always. I think HSC is supposedly 2 years away for Japan and Mexico, but we will see how effective that really is on 100% of people, or if it gives varying results or varies on what type norwood scales is most effective on.