Thanks for your reply!
So SW033291 inhibits 15-PGDH so levels of PGE1, PGE2 and PGF2a are increased.
PGE1 and PGE2 inhibit collagen production, but I see your point about dermarolling, so the increase of PGE2 should be good.
PGF2a is bad for skin according to this:
But the effects can be counterbalanced by PGE1 and PGE2 increase, so it is difficult to SW033291 safety.
But now I have a question, instead of SW033291, it would not be simpler and safer to use directly PGE2 as @westonci did?
PGE2 is probably only bad for skin so far as it gets converted to PGF2a. PGF2a is only somewhat increased by SW033291, while the increase in PGE2 is much more pronounced.
Standalone treatment with PGE2 doesn't come close to raising PGE2 levels as much as combining it with SW033291, as you can see in the study I linked in the OP. The combination of those two could be a major breakthrough in the treatment of male pattern baldness.