Isn’t Follica Supposed To Be Out In The Next 1-2 Years?

hanginginthewire

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That number was taken out of context at the time and many people today associated with the efficacy of the treatment

Now, what will this first iteration of Follica consist of? minoxidil and a selected modality of skin disruption, or more than one.

If you read the studies in humans you will see that the numbers of hair per sq. expected could be significantly higher, and that is why Follica will kick *** especially compared to previous drugs, snake oils, brotions, etc

Do your homework fella

Are you affiliated with Follica?
 

hanginginthewire

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yeah, im cotsarelis. Feel free to ask me about anything you want dude

:)

What’s your balding situation? What treatments are you most hopeful about? Do you have Puretech stock? I’m genuinely asking. Everyone is understandably pessimistic about the hair loss industry, when I encounter a (semi?) optimist who isn’t an obvious loon or fantasist I want to pick your brain.
 

Kagaho

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LOL OK, my hair situation has changed drastically in recent months thanks to the restarting of minoxidil (I had not had luck when I used it together with finasteride) and of course dermarolling.

I do not have any affiliation with Follica, I wish!

When I have time I will make a thread of my personal situation.

What bothers me a little about this thread is that a lot of people spend too much time complaining and they do not look for success cases. there are and many.
 
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hrplz

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Obviously plenty of reasons to be skeptical given all of the delays. Here's my optimistic take with perhaps a tiny bit of realism:

1. They said they would begin an optimization study in the first half of 2018 and that happened. Admittedly, they had to change time frames more than once, but they met a stated goal. In the hairloss world, that counts for something.
2. They said they would begin both the optimization study and their pivotal trial in the first half of 2018. Given how close those two events are being initiated, they must feel that the pivotal trial is a practical certainty after the optimization study (I know, I know! But we're focusing on the positives.)
3. We'll potentially know within the next 2.5 months if the pivotal trial has started - which would be the first Phase 3 trial for a hairloss drug/treatment in how many years?? (I actually don't know the answer to this question.)
 

dermrafok

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hahaha. Here people just say nonsense!!!! Some will get an unpleasant surprise. They are very very close!!!
 

Murkey Thumb

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But have you ever tried dermarolling?
I'm been derma rolling for 10 years. Still bald!

I admit that i did have some success when i first started but i was also using a 15% minoxidil solution from Dr Lee at the time. The effects lasted for about 9 months then i started losing ground again after Dr Lee got shut down by the FDA. I have tried to replicate the formula but nothing has really worked as well. The 15% played havoc with my skin & eyes too so it wasn't a pleasant experience.
 
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brohawk

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I'm been derma rolling for 10 years. Still bald!

I admit that i did have some success when i first started but i was also using a 15% minoxidil solution from Dr Lee at the time. The effects lasted for about 9 months then i started losing ground again after Dr Lee got shut down by the FDA. I have tried to replicate the formula but nothing has really worked as well. The 15% played havoc with my skin & eyes too so it wasn't a pleasant experience.

Are you just using it lightly for absorption, or going hard until you have erythema/purple skin? Added a GSK3b-inhibitor for activating wnt? Any other aspects of what Follica has included in their patents? Kitchen sink is where it's at and Follica knows it. May not bring a NW7 back to dense NW1, but that's certainly what they're trying to achieve and why it's taken them all these years to do it, IMO.
 

Murkey Thumb

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Yeah I have used it for absorption in the past on and off using a 0.5 roller. Still bald!

I have just started something different a couple of weeks ago which is loosely based upon what Follica is doing after i noticed a similar protocol on http://www.worldhairloss.org/index.php/forums/viewthread/9 My best guess is that they are not going to be using Lithium or Genistein in their protocol and i was thinking of swapping them for something more potent but cant really be bothered as i don't really have the time or energy. If its successful I will report back, if not i will go back to plan 'W' and say nothing.

Wounding 1.5mm x 1 weekly
Lithium chloride x 2 daily
Genistein x 2 daily
Essengen (minoxidil & 0.05% finasteride) x 1 daily
castor oil + dmso x 1 over night
 

Murkey Thumb

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0.5 was recommended by my hair surgeon, like i said earlier it only really worked with 15% minoxidil + acetic acid and what ever Dr Lee was using at the time. However if you look very closely at my scalp there is definitely scarring from rolling. I don't really know where i would put myself in a Norwood scale probably a Norwood 4 V would be the closest but i had a fue to rebuild the hairline so who knows? Crown is bare and mid scalp defuse to a point were i buzz to a number 3 just to look ok.
 

Kagaho

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0.5 was recommended by my hair surgeon, like i said earlier it only really worked with 15% minoxidil + acetic acid and what ever Dr Lee was using at the time. However if you look very closely at my scalp there is definitely scarring from rolling. I don't really know where i would put myself in a Norwood scale probably a Norwood 4 V would be the closest but i had a fue to rebuild the hairline so who knows? Crown is bare and mid scalp defuse to a point were i buzz to a number 3 just to look ok.

You are making the right decision by choosing a 1.5mm dermaroller.
 

Noisette

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2018 is suppposed to be such a game changer for hair loss treatments. Where is Follica at?
Hey @hanginginthewire
" Follica has completed its clinical-stage development of a next-generation device and drug combination product " and they are developping next-generation, proprietary compounds (pre-clinical testing)
Now, Follica is in the middle of the optimisation study, then following that they will begin their pivotal trial (Phase 3)
 

Murkey Thumb

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I am quietly optimistic about Follica far more so then i have been about Histogen/Brotzu which i have never had much faith in. It wont be a perfect treatment as suspect you will have to carry on getting wounded at a clinic every couple of years just to maintain and you with still have to follow a strict regime. However even 10-20% more hair would have an amazing effect!
 

Noisette

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I am quietly optimistic about Follica far more so then i have been about Histogen/Brotzu which i have never had much faith in. It wont be a perfect treatment as suspect you will have to carry on getting wounded at a clinic every couple of years just to maintain and you with still have to follow a strict regime. However even 10-20% more hair would have an amazing effect!
+1 And for Follica is not "just to maintain" what we have. According to them, they can create New hair follicles (follicular neogenesis), and reorganizing existing hair structures...
 

THALL

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+1 And for Follica is not "just to maintain" what we have. According to them, they can create New hair follicles (follicular neogenesis), and reorganizing existing hair structures...
Yes, but the newly created hair follicles will not be immune to male pattern baldness, at least after some time. That is what is predicted, so you will have to get the treatment again, in one, two or hopefully more years
 

Murkey Thumb

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+1 And for Follica is not "just to maintain" what we have. According to them, they can create New hair follicles (follicular neogenesis), and reorganizing existing hair structures...
Yeah that is true but those hairs will still fall foul to DHT, it will regenerate new hairs but those will still have the characteristics of the old ones. Therefore more new follicles will be required every couple of years.
 
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