Everyone, I've been off this forum for a couple weeks, but I want to give an update: Unfortunately, I've given up hope on seti.
To recount my experience:
I started taking Kane's seti on Nov 10th at 1g/day. I switched to Lyphar's seti at 2g/day starting December 28th or so. So I'm ~10 weeks in on Lyphar and almost 4 months in from when I started Kane's seti.
In addition to this, I started minoxidil in early December, applying only to the crown and top of my head (on my spot that was thinnest ie a traditional bald spot). I've reported increased shedding but no additional sides in previous posts on this thread. Others attributed that to the minoxidil, which makes sense. This shedding has continued to this day.
Here's my problem:
At this point, the crown of my head has thicker hair (in fact, what was a small bald spot is now gone), but the front, sides, and nape of my head are all substantially thinner.
In other words, it's apparent to me at this point that the minoxidil is working, at least to some extent, but the seti is not.
I fear that the shedding I've experienced is not from the drugs at all but simply an increased rate of natural hair loss, which is offset on my crown by the minoxidil. And I fear that the seti is simply not effective, causing thinning everywhere else. I fear that the positive results that wes got stem from the PGE2 treatment that he underwent, rather than from the seti. This lines up neatly with his most recent posts on this thread. It's also something I was asking back on Jan 2nd on this thread:
I'm obviously very bullish on seti, and I'm betting my hair on it, but I think this is a good point.
@westonci, I applaud you for being the canary in a coal mine here, and your experience has provided great data points on sides, etc. However, Seti isn't supposed to cause regrowth, just maintenance. But it seems like most of the enthusiasm around your photos/progress is from the regrowth. You mentioned your hair is thickening and are attributing it to the seti. Could that be caused by the other parts of your regimen like the PGE2 and Dermastamping?
So I "threw in the towel" on trying to do this without an anti-androgen, and I started fina this past weekend. I was on it just fine for years w/o sides, stopped for a bit, and then started it again. I got sides when I started it again, but there was also a lot going on in my life then and so I'm not positive it was the drug. I'm going to give it another shot because I have to act quick to save my hair.
For those out there who don't want to do fina (which I presume is almost everyone on this forum), it sounds like adding PDE2 to your routine could be the way to go. If I get bad sides on fina, I may stop and try that.
***Note that despite my findings, I'm going to continue the 2g/day seti routine until Allergan announces results of the clinical trials this summer. That will be a 6-8 month trial, and I feel like testing any hair loss drug does take time. If their tests show super positive results, but also indicate strong shedding in the first 3 months, then well, that could mean seti is effective after all, and I'll stay on it. But if their test results are lackluster, I'll quit.
As an aside, Pigeon reported something similar about thinning on the front and sides in post #298 in this thread:
https://www.hairlosstalk.com/intera...really-high-doses.105459/page-15#post-1583139
I think it's a weird coincidence.
Although I hate to be a bummer, I think too often people don't post lackluster or negative results. I think its important we all share results, whatever they are, so we can triangulate to the most effective treatment. Regardless of your regimen, good luck everyone!