Italian Hair Loss Lotion To Hit The Market In 2016

CapiLarry

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I’d contribute if you set it up and were willing to go.
Apparently no one on IESON will be able to go.

So I thought about it and f*** it, I might go and film it.

The only inconvenience is that I live on the other side of Italy and I am still a poor student.
If I setup a GoFundMe for 200€, would you be interested? Really I only need money for the train, conference and one night hotel.

I'd be willing to contribute as well. Set it up!
 

ZenHead

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If that is the case then it will also reduce DHT on other parts of the body right?
No. Let me state again - DHT synthesis will NOT be altered in the body. The DHT in your scalp will be unable to bind to the androgen receptors in the scalp, stopping the DHT cascade which leads to male pattern baldness.

Let me put it this way - if you applied equol to your prostate, the DHT would not bind to the prostate's receptors (this is why equol is being looked at as a BPH treatment). If you applied it to your leg, the DHT would not bind to the legs androgen receptors (maybe less leg hair?). You get the point
 

vegetassj

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Sounds clever. Billion dollar question: Why noone is using this euqol then????

Does not seem like a big secret to me. Looks like merck could easily combine this with rogaine to beat finasteride out of the market. Or why does noone mix it in his own minoxidil?
 

Afro_Vacancy

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Things that I do not know, and would like to know,

1) How will the DHT inhibition of the brotion compare to the ~65% DHT reduction of finasteride, the ~90% reduction from dutasteride, and the ~70% blocking of androgen receptors from RU?
2) Will it be dose-dependent, or will a single swipe of the brotion saturate the effect?
3) How much of the S-equol will go systemic?
 

Afro_Vacancy

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It is not the same, but a bit similar... RU binds to the androgen receptor. Equol binds to DHT which prevents it from binding to the androgen receptor.

Also, some more clarification in regards to side effects: Testosterone can either convert into DHT or Estradiol. Finasteride inhibits the conversion of T to DHT, so by default it converts to Estradiol. The excess Estradiol is most likely why sexual side effects occur in many finasteride users. This lotion does not have this flaw - your hormonal levels will not be altered

There's no indication that this is true.

By the way, testosterone can also bind to SHBG.
 

ZenHead

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There's no indication that this is true.

By the way, testosterone can also bind to SHBG.
Fair enough, there is actually no solid answer on where finasteride sexual side effects occur. But, I will say from my research on people with sides who had their hormone levels tested, elevated estradiol was common among most of them
 

Royaume

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Apparently no one on IESON will be able to go.

So I thought about it and f*** it, I might go and film it.

The only inconvenience is that I live on the other side of Italy and I am still a poor student.
If I setup a GoFundMe for 200€, would you be interested? Really I only need money for the train, conference and one night hotel.

Yes, i am sure that we will get the 200 Euros for you. This should not be an issue. We really need someone who film it. This could be the most important event for us, especially in 2018.
 

Afro_Vacancy

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Fair enough, there is actually no solid answer on where finasteride sexual side effects occur. But, I will say from my research on people with sides who had their hormone levels tested, elevated estradiol was common among most of them

Studies of people with PFS have, to the best of my knowledge, found no meaningful differences in levels of serum hormones. Finasteride sides are a tough nut to crack. What has been shown are differences in hormonal levels of the cerebrospinal fluid, but the sample size was small.

That supports the notion that finasteride sides are actually due to its effects on neurosteroids. Given that this lotion should yield fewer sides, as we don't expect topical s-equol to rampage through neurosteroid levels and transform them the way finasteride does.
 

Afro_Vacancy

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If it's only 200 euros there may be multiple people willing to contribute.

A lot of people were disappointed by Hellouser's trip to Tokyo. He took money and seemingly put in much less effort and produced far less content than he did on his trip to Miami a year prior. It was a very underwhelming result and it validated the people who said that funding him was pointless and that he was just getting a free trip out of it.
 

ZenHead

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Studies of people with PFS have, to the best of my knowledge, found no meaningful differences in levels of serum hormones. Finasteride sides are a tough nut to crack. What has been shown are differences in hormonal levels of the cerebrospinal fluid, but the sample size was small.

That supports the notion that finasteride sides are actually due to its effects on neurosteroids. Given that this lotion should yield fewer sides, as we don't expect topical s-equol to rampage through neurosteroid levels and transform them the way finasteride does.
Young men taking Finasteride - after a few months
DHT very low (reduced by 70%)
Estrogen (estradiol) - elevated (excess testosterone is converted into estrogen only, instead of E2 and DHT. Possibility of feminization of the body)
Prolactin: elevated (increasing the level of estrogen causes increased prolactin)
Impact on libido: Lower libido due to high levels of Prolactin, Estradiol and low level of DHT.

http://finasteridesyndrome.blogspot.com/p/dht-role.html

I know this is not a scientific study, but there is plenty of evidence out there that claims that what I posted about elevated estradiol and its relation to side effects is true. I don't mean to get off topic, but I just wanted to share why I think this "lotion" is special - due to it not affecting hormones (and elevating estradiol). That's all I'm saying man.
 

fuDHTck

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If it's only 200 euros there may be multiple people willing to contribute.

A lot of people were disappointed by Hellouser's trip to Tokyo. He took money and seemingly put in much less effort and produced far less content than he did on his trip to Miami a year prior. It was a very underwhelming result and it validated the people who said that funding him was pointless and that he was just getting a free trip out of it.
Well I would film only Brotzu presentation and make sure i have good audio quality of it.

I will let you know soon if I will go or someone else will.
 

Royaume

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Well I would film only Brotzu presentation and make sure i have good audio quality of it.

I will let you know soon if I will go or someone else will.


Start the gofundme page. I think the areata girls will attend the sitri conference but I dont like them. They just focus on areata and give a f*** on Androgenetic Alopecia.

Come on guys. We reached over 700 pages. It would be enough if we donste 5-10 Euros.... We can reach this very fast.

We need a fast update. Br1 should donate 50 Euro for his pessimistic attitude.
 

fuDHTck

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yeah, I just want to make sure I can actually film.

I know you wouldn't even trust my words lol
 

Btg

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Young men taking Finasteride - after a few months
DHT very low (reduced by 70%)
Estrogen (estradiol) - elevated (excess testosterone is converted into estrogen only, instead of E2 and DHT. Possibility of feminization of the body)

Prolactin: elevated (increasing the level of estrogen causes increased prolactin)
Impact on libido: Lower libido due to high levels of Prolactin, Estradiol and low level of DHT.

http://finasteridesyndrome.blogspot.com/p/dht-role.html

I know this is not a scientific study, but there is plenty of evidence out there that claims that what I posted about elevated estradiol and its relation to side effects is true. I don't mean to get off topic, but I just wanted to share why I think this "lotion" is special - due to it not affecting hormones (and elevating estradiol). That's all I'm saying man.
well there are some studies claiming DHT is better than testosterone in releasing NO2 which is the primary erection substance so this alone should cause a bit weaker erections , but there are a shitloads of factors concering erections , probably neurosteroids play a role too so who knows
 

kawnshawn

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Sounds clever. Billion dollar question: Why noone is using this euqol then????

Does not seem like a big secret to me. Looks like merck could easily combine this with rogaine to beat finasteride out of the market. Or why does noone mix it in his own minoxidil?
Things that I do not know, and would like to know,

1) How will the DHT inhibition of the brotion compare to the ~65% DHT reduction of finasteride, the ~90% reduction from dutasteride, and the ~70% blocking of androgen receptors from RU?
2) Will it be dose-dependent, or will a single swipe of the brotion saturate the effect?
3) How much of the S-equol will go systemic?
Slow your roll, you're asking stuff that no one can answer for fact since no one is using the lotion or helped developed it and Beps will continue to be as vague as possible. Just wait until April.
 

kawnshawn

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Well I would film only Brotzu presentation and make sure i have good audio quality of it.

I will let you know soon if I will go or someone else will.
I imagine that it will be spoken in Italian so someone is gonna have to provide a translated synopsis of it.
 
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