It's all to do with inflammation..

[1.....]

what are people with pre-mature hairloss best route if this anti inflam. thing isnt enought?

 

[helpwithhair]

there seems to be a hell of a lot of pills that could help.

Any recommendations?

 

[decro435]

I do not buy the theory that claims hair follicles are sensitive to D.H.T. because D.H.T. is the main androgen in every part of the body except the muscle. The muscles main androgen is testosterone.

DHT might be the main androgen in every part of the body except the muscle, but what difference does that make? Hair follicles on the head are different to those on the body and they are sensitive to androgens. The general theory states that DHT attaches itself to the androgen receptors in the Dermal Papilla. Thus causing it to release growth surpressing chemicals. Body hair is effected oppositely and androgens actually stimulate growth.

what are people with pre-mature hairloss best route if this anti inflam. thing isnt enought?

there seems to be a hell of a lot of pills that could help.

Any recommendations?

My route to take for a premature Androgenetic Alopecia sufferer would be:

- (.25mg) or less of Finasteride and on the first sign of side effects quit. None of this "Ride it out" bullshit that inexperienced posters claim. Though, you can be a bit more lenient if you are older. Personally after a lot of deliberation I had to quit the drug and I'm glad I did. It wrecked havoc on my body and it's effects are still present after 5 months of going cold turkey on it. Hate to say it but I should have listened to those people claiming the potential irreversible effects.

- Cucurmin.- Too many studies showing it's benefits. Could a key ingredient to a successful regimen.

- Fish oil/Krill oil - Why don't people take this? It has so many well documented benefits.

- Nizoral(Ketoconazole) - Studies prove it's benefits.

- T/gel(Coal Tar) - I like it, I feel it might even be a more important

- As many antioxidant and anti-inflammatory supplements as possible, preferably coming from food consumption.

- Topical of Olive oil and Vitamin E. I know it depends on the person and how much they really want to keep their hair, but a topical of this oil applied at night and washed out in the morning make my head feel great. It's also very cheap. Extra-virgin Olive oil is best. Other oils that could be used are Jojoba oil, Aloe Vera, Tea tree, Lavender and many more. Many have "alleged" benefits for Androgenetic Alopecia sufferers.

There's a good bit more that I could add, but the jury is out on a lot of it.

 

[decro435]

Seriously about all of them..

-Extreme decrease in Ejaculate.
-Weak, soft erections.
-Testicular pain
-Penile and testicular shrinkage.
-Weight gain.
-Loss of muscle.
-Depression.
-Memory problems.
-Weird feeling around nipples.
-Anxiety

Now you'd think that someone would jump off of the drug when they saw the first sign of side effects. But, they creep up on you so quickly.

 

[Thickandthin]

Seriously about all of them..

-Extreme decrease in Ejaculate.
-Weak, soft erections.
-Testicular pain
-Penile and testicular shrinkage.
-Weight gain.
-Loss of muscle.
-Depression.
-Memory problems.
-Weird feeling around nipples.
-Anxiety

Now you'd think that someone would jump off of the drug when they saw the first sign of side effects. But, they creep up on you so quickly.

I have all of those now (except the nip thing) and I'm not even on finasteride.

 

[decro435]

I hate to say it but no not really, erections aren't half as strong as they were. Stupid to have to put up with that at 19, but I took the choice to use Finasteride. Hopefully, over the next year or so they'll get better.. :dunno:

 

[barcafan]

get some bloodwork done. You could have permanently shut off 5AR2.

alot of idiots here will say that DHT is a 'useless' hormone, LOL

 

[decro435]

Yeah all those tools, telling un-educated, gullible young guys to ride it out. Finasteride is a very potent, dangerous drug. Actually, I wouldn't reccomend it to anyone under 30. Unfortuenatly, there will still be hoards of young guys jumping on this drug, avoiding the stark warnings just like I did. I don't blame half of them either, losing your hair so young is extremely worrying.

 

[Cassin]

Yeah all those tools, telling un-educated, gullible young guys to ride it out. Finasteride is a very potent, dangerous drug. Actually, I wouldn't reccomend it to anyone under 30. Unfortuenatly, there will still be hoards of young guys jumping on this drug, avoiding the stark warnings just like I did. I don't blame half of them either, losing your hair so young is extremely worrying.

My biggest problem with guys using finasteride is the fools who order it off the internet having no clue what it really is.

 

[Thickandthin]

Yeah all those tools, telling un-educated, gullible young guys to ride it out. Finasteride is a very potent, dangerous drug. Actually, I wouldn't reccomend it to anyone under 30. Unfortuenatly, there will still be hoards of young guys jumping on this drug, avoiding the stark warnings just like I did. I don't blame half of them either, losing your hair so young is extremely worrying.

My biggest problem with guys using finasteride is the fools who order it off the internet having no clue what it really is.

Do you hang out at the factory where your finasteride pills are created? How do you know the stuff you get from your local pharmacy isn't fake?

 

[Cassin]

Yeah all those tools, telling un-educated, gullible young guys to ride it out. Finasteride is a very potent, dangerous drug. Actually, I wouldn't reccomend it to anyone under 30. Unfortuenatly, there will still be hoards of young guys jumping on this drug, avoiding the stark warnings just like I did. I don't blame half of them either, losing your hair so young is extremely worrying.

My biggest problem with guys using finasteride is the fools who order it off the internet having no clue what it really is.

Do you hang out at the factory where your finasteride pills are created? How do you know the stuff you get from your local pharmacy isn't fake?

Ok...do I really need to explain the difference between FDA approved finasteride I get from Walgreens and stuff bought from some website?

I wont waste my time if you can't figure that out.

 

[decro435]

Hey decro are you still shedding hair, is your male pattern baldness progressing, or has it stable now? The reason I ask this is because, if your A5R was shut of completly, you would not still be experiancing male pattern baldness.

No it's still progressing, not as fast as it was, but it's progressing. When I start my new regimen of mostly Anti-inflammatories, Ketoconazole etc. I will keep track of it in my "My Story" thread.

I believe that the damage done to me, was done during the use of Finasteride and my body is now recouperating. Whether or not the erection problems are permenant is anyone's guess.

 

[Thickandthin]

Ok...do I really need to explain the difference between FDA approved finasteride I get from Walgreens and stuff bought from some website?

I wont waste my time if you can't figure that out.

Doesn't matter if it's "FDA approved". It can be still counterfeited just as easily as Fincar made in India can be. In fact, the brand name Proscar and Propecia are more likely to be counterfeited than a no name, Indian generic drug which costs pennies. Just pointing out the logical fallacy in thinking that because you bought a drug on US soil means it is immune to being fake - because its not.

There are no statistics for fake fincar, not even a single valid suspicion actually, and in fact the high majority of people on this very website with success stories are using it.

 

[Thickandthin]

Hey decro are you still shedding hair, is your male pattern baldness progressing, or has it stable now? The reason I ask this is because, if your A5R was shut of completly, you would not still be experiancing male pattern baldness.

No it's still progressing, not as fast as it was, but it's progressing. When I start my new regimen of mostly Anti-inflammatories, Ketoconazole etc. I will keep track of it in my "My Story" thread.

I believe that the damage done to me, was done during the use of Finasteride and my body is now recouperating. Whether or not the erection problems are permenant is anyone's guess.

The paranoia in your mind is permanent - that's for sure.

 

[baller234]

Apparently spironolactone is a strong inhibitor of inflammatory cytokines.

http://sciencelinks.jp/j-east/article/2 ... 569731.php

http://cat.inist.fr/?aModele=afficheN&cpsidt=17767904

Perhaps the anti-inflammatory properties of spironolactone play a stronger role in preventing hair loss than its anti-androgen effects.

 

[decro435]

Baller, have you ever used spironolactone?

Well, if you haven't there is an immediate cooling sensation, it makes your head feel great. I attribute this mostly to the fact that is an anti-inflammatory. Actually, the same can be seen with Olive oil. A naturally occurring chemical found in extra-virgin olive oils is a non-steroidal anti-inflammatory agent called oleocanthal. I noticed when applying Olive oil to my head, my head would feel great and relieved from the usual tightness and pain. I also noticed that if I applied a lot I would wake up in the morning with a weird sensation in the back of my throat. Fast-forward a few months and I come across this article; http://www.sciencedaily.com/releases/20 ... 075427.htm

Basically, it claims that scientists discovered that Olive oil posseses the same anti-inflammatory properties as Ibuprofen. They noticed that both Olive oil and Ibuprofen induced that weird sesation in the back of the throat and the studies began from there. If you go back through the archives, you will notice that I posted a thread on "Olive oil" and claimed that it had significantly slowed down my hair loss. I didn't know how or why, but it helped immensly. Now I understand that it was due to it's anti-inflammatory properties.

This further back's up the theory that a regimen of anti-inflammatories could be extremely beneficial in the treatment of Androgenetic Alopecia. Olive oil was always as ancient cure for hair loss, I guess it might have actually worked to a certain degree.

 

[dpdr]

...

 

[baller234]

Yes, I use it topically and internally. I'm assuming you're refering to topical spironolactone when you refer to the cooling sensation. If you use Dr. Lees solution, this cooling sensation could be due to the aloe vera as this is the base for his cream.

Aloe vera is also suppose to be a strong anti-inflammatory.

 

[litcII]

Might be kind of a dumb question, but is the cucurmin supposed to eaten, or applied topically?

 

[decro435]

It's generally taken orally, but it can be applied topically. Sometimes this results in irritation. I'd reccomend taking it orally though, just because I have yet to see a study done on it's topical effects.