Not exactly because of the 12 accounts of accelerated loss but I meant that most people have an easier time maintaining their crown then their hairlines when they are losing ground. I'm less surprised when a NW4 maintains or improves over 4 years then when a NW1.5-2 does.
Kintor has started Phase 3 trial in China for Pyrilutamide
- Thread starter Micky_007
- Start date
- Reaction score
- 142
Nah im NW1 (real)slighly diffused. dutasteride made my hair thin asf and i start shedding 300 hairs 10 months straight lol. I'm on finasteride now and hair is already less thin and looking better.
I know about the studies tho, idk how it's possible. But i actually fucked my hair way worse than without medication.
- Reaction score
- 2,105
Probably just a better responder due to genes. Same way for me
And most of them quit before they get to the other side of the shedding and the eventual recovery, leaving you with tons of reports of from dumb panicked people and the perception that dutasteride ruins hair.
You can also search the same thing for finasteride and get the same results. 9/10 times they just quit during the shedding period.
Will finasteride loose effectiveness after 10 + years?
- Reaction score
- 5
Saw this on tressless, don’t know if it was posted here. Says phase 2 results June 2022.
- Reaction score
- 68
Yes we were and are eagerly waiting for June, thanks for that document anyway.
Hope that the leaked results aren't bullshit haha !! Gonna be a fun wait ! Last time I was excited for results was for... Brotzu and their conference lmao
"Diameter doesn't change"
- Reaction score
- 3,659
Yes we were and are eagerly waiting for June, thanks for that document anyway.
Hope that the leaked results aren't bullshit haha !! Gonna be a fun wait ! Last time I was excited for results was for... Brotzu and their conference lmao
"Diameter doesn't change"
f*** if only the diameter didn't change, that would at least mean it had not gotten any worse, but it couldn't even do that.
- Reaction score
- 173
What's the deal with group buys, are they legal or not so much?
- Reaction score
- 142
I really start to hate it when i see a notification popping op on this or the HMI topic to only find out there are more stupid questions being asked.
inmyhead
Senior Member
- Reaction score
- 1,018
I think you got the wrong price. Where do you see 280USD for 5g?Not sure if I'm allowed to say company names? But I might give it a go.seems expensive but $279 = £205 for 5000mg at 10mg a day is less than a pound a day, that's less than minoxadil.
I'm not American but they seem to be recruiting for trials
ClinicalTrials.gov
clinicaltrials.gov
Edit: actually I have a couple questions:
Is selleckchem legit?
What vehicle should I use, currently I use zix so can I just use alcohol/distilled water?
How is this stored in the freezer like RU?
Remember this was a chinese study. Asian men tend to respond better to antiandrogens than caucasians.
I wouldnt expect KX to be more effective than finasteride or dutasteride. Excellent addition to the arsenal though.
As somebody mentioned in the discord, Dutasteride results in a phase III Korean study were 12.2/cm2. Koreans and Chinese are similar enough, which means that if the 22.5/cm2 result is true it should be significantly more effective than dutasteride.
If it can achieve long-term maintenance even with some minimal regrowth or thickening it's already a win in my book. I'm not in the pursuit of a juvenile NW1 hairline and I don't harbor any grand delusions, I'm quite happy to live with my NW3 hairline as long as it doesn't get any worse and becomes slightly more revitalized than it is right now.
Cool bro. Thats a realistic mindset. You can still go for some regrowth with DY dermarolling/stamping + minoxidil.
- Reaction score
- 179
just a friendly reminder that 6 months result of breezily was 21/cm^2 in TAHC. then after 12 months it went totally to sh*t. Kintor does not plan to do a 12 month phase 3 trial. they are both topical anti androgens and have a very comparable mechanism of action. so even if the leaked results were to be accurate and the side effect profile was to be favorable, who says that pyralutamide shares not the same property that it cannot maintain the regrowth for more than half a year. and we would never know because they do not have to do a 12 month trial. maybe they will have to do one for the FDA once they are in phase 3 in the US. but that will take another 1-2 years minimum
I still do not understand why breezula did so well initially and then so poorly when other anti androgens like finasteride or dutasteride really start to show the best results after 12-15 months. its strange because anti androgens take a long time to show their positive effects however with this one it seems to be potent initially and then diminish(breezula). personally I am hopeful that Pyrilutamide does not have this property
I was under the impression that Pyrilutamide was an androgen degrader. If so then its mode of action is far different than an anti-androgen like Breezula or RU. The safety profile would also be better.