J
jonson
Guest
Hi
Could it be that l arginine increase hairloss?
Did you hear about that?
Could it be that l arginine increase hairloss?
Did you hear about that?
squeegee
Banned
- Reaction score
- 132
israelite said:
Isrealite! don't garbage it!! just add Dl of l-citrulline malate or L-Norvaline to it.. you will be fine!! http://purebulk.com/l-norvaline
read this! really good read : http://www.lmreview.com/articles/view/l ... e-part-II/
squeegee
Banned
- Reaction score
- 132
Bryan said:
update your stuff Bryan... I am a gym freak and know a lot about arginine..you are so late in the news..
Supplemental L-arginine is readily absorbed; however, ~50% of ingested L-arginine is rapidly converted in the body to ornithine, primarily by the enzyme arginase.16 As noted above, in the presence of oxidized LDL, arginase activity is increased, and arginase competes with NOS for L-arginine in its role as a substrate for NOS, which results in impaired production of NO and increased production of ROS by NOS.
L-citrulline may be a better option. L-citrulline is readily absorbed and efficiently converted to L-arginine. But its conversion does not take place in the intestine or liver, and therefore not only does not induce tissue arginase, but inhibits its activity. Upon entering the kidney, vascular endothelium and other tissues, L-citrulline is readily converted to L-arginine, raising plasma and tissue levels of L-arginine and enhancing NO production.14 Published data indicates that L-citrulline has relatively better absorption and systemic bioavailability than L-arginine.
squeegee
Banned
- Reaction score
- 132
Jan. 9, 2004 — Topical L-arginine cream improves blood flow and temperature in the feet of diabetics, according to the results of a preliminary trial published as a letter in the January issue of Diabetes Care.
"This pilot study showed that arginine does increase blood flow, but it is not yet clear if this translates into fewer foot ulcers or better healing of ulcers," American Diabetes Association Vice President Robert Rizza, MD, told Medscape. He is a professor of medicine in the division of endocrinology and diabetes at the Mayo Clinic in Rochester, Minnesota, and was not involved in this study.
L-arginine, an amino acid classified as a dietary supplement, is the biochemical precursor of nitric oxide, which controls local blood flow by relaxing endothelial smooth muscle. In diabetes, L-arginine levels are reduced while levels of asymmetric dimethylarginine, an inhibitor of the enzyme that converts L-arginine to nitric oxide, are elevated. Transdermal delivery of exogenous L-arginine via patented technology is said to restore blood flow by reversing these biochemical defects.
In this double-blind, vehicle-controlled, crossover-design pilot with washout periods of one week, 16 subjects with diabetes and impaired foot circulation were enrolled and 13 completed the study. With L-arginine cream, average Doppler flow increased 33% at the metatarsal and 35% at the Achilles tendon, and average temperature increased 5 degrees at the metatarsal and 8 degrees at the great toe.
"That is a huge amount," study author Eric T. Fossel, PhD, told Medscape. "It is true that this was a small study, but these are very convincing statistics." Dr. Fossel is president of Strategic Science and Technologies in Wellesley, Massachusetts, which holds the patent for L-arginine cream.
Because the effect of L-arginine persisted throughout the washout period, Dr. Fossel altered the analysis to determine the effect from cumulative exposure to L-arginine throughout the study. This eliminated the possibility of comparing active cream with placebo.
Dr. Rizza called these findings "intriguing but preliminary" and recommended additional research to determine if the cream has any clinical benefit in preventing or reducing amputations or other foot complications.
"We need better treatments, but there are many things that diabetics can do to reduce their risks," he said, urging daily foot inspection, better glucose control, exercise, quitting smoking, and protecting the feet with well-fitting shoes.
"This pilot study showed that arginine does increase blood flow, but it is not yet clear if this translates into fewer foot ulcers or better healing of ulcers," American Diabetes Association Vice President Robert Rizza, MD, told Medscape. He is a professor of medicine in the division of endocrinology and diabetes at the Mayo Clinic in Rochester, Minnesota, and was not involved in this study.
L-arginine, an amino acid classified as a dietary supplement, is the biochemical precursor of nitric oxide, which controls local blood flow by relaxing endothelial smooth muscle. In diabetes, L-arginine levels are reduced while levels of asymmetric dimethylarginine, an inhibitor of the enzyme that converts L-arginine to nitric oxide, are elevated. Transdermal delivery of exogenous L-arginine via patented technology is said to restore blood flow by reversing these biochemical defects.
In this double-blind, vehicle-controlled, crossover-design pilot with washout periods of one week, 16 subjects with diabetes and impaired foot circulation were enrolled and 13 completed the study. With L-arginine cream, average Doppler flow increased 33% at the metatarsal and 35% at the Achilles tendon, and average temperature increased 5 degrees at the metatarsal and 8 degrees at the great toe.
"That is a huge amount," study author Eric T. Fossel, PhD, told Medscape. "It is true that this was a small study, but these are very convincing statistics." Dr. Fossel is president of Strategic Science and Technologies in Wellesley, Massachusetts, which holds the patent for L-arginine cream.
Because the effect of L-arginine persisted throughout the washout period, Dr. Fossel altered the analysis to determine the effect from cumulative exposure to L-arginine throughout the study. This eliminated the possibility of comparing active cream with placebo.
Dr. Rizza called these findings "intriguing but preliminary" and recommended additional research to determine if the cream has any clinical benefit in preventing or reducing amputations or other foot complications.
"We need better treatments, but there are many things that diabetics can do to reduce their risks," he said, urging daily foot inspection, better glucose control, exercise, quitting smoking, and protecting the feet with well-fitting shoes.
- Reaction score
- 42
Jacob said:
Sure! We know what many (or most) of the things in Prox-N are, because they're right there on the label. But there's no such label for Proxiphen, unfortunately. We know about a few of the things in Proxiphen, but that's all we can say about it.
Jacob
Senior Member
- Reaction score
- 44
I don't know if this is worth looking into: http://www.neogenis.com/
First saw it at this place: http://www.healthtruthrevealed.com/item-NEO40.html ..was an article on it a few days ago..disappeared.
Same company that sells that beet root powder..as posted about here(see the NO connection): http://www.hairlosstalk.com/interact/viewtopic.php?f=36&t=69050
First saw it at this place: http://www.healthtruthrevealed.com/item-NEO40.html ..was an article on it a few days ago..disappeared.
Same company that sells that beet root powder..as posted about here(see the NO connection): http://www.hairlosstalk.com/interact/viewtopic.php?f=36&t=69050
Jacob
Senior Member
- Reaction score
- 44
Bryan said:
Oh..so now there are "mysterious ingredients" in Prox-N as well. If it's not on the label..it shouldn't be in it.
Again..Just imagine..anything we talk about here Bryan can say- it may also be in Proxiphen! And now Prox-N as well...it seems.
Why people would spend that kind of money on something that doesn't have a full ingredients list..and even NO list... :shock: