Meiji Seika Pharma teams up with Dr. Tsuji of the Riken Center

[distracted]

I HIGHLY doubt his work was destroyed. He's probably just waiting for a more appropriate time to announce his findings.

Or..you know.. just the familiar delays that we are no stranger to.

 

[Tracksterderm]

Hey Swoop, did you send send any email to Tsuji and if so, any replies about the announcement?

 

[Swoop]

Hey guys, I didn't heard anything yet whatsoever. I'm going to e-mail him next week in Japenese so it makes it easier for him to respond in a more detailed fashion!

 

[distracted]

Hey guys, I didn't heard anything yet whatsoever. I'm going to e-mail him next week in Japenese so it makes it easier for him to respond in a more detailed fashion!

Damn Swoop nice new avatar. Who needs hair with abs like that!

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But thank you! Tsuji updates are the best kind of updates

 

[Pray The Bald Away]

Hey guys, I didn't heard anything yet whatsoever. I'm going to e-mail him next week in Japenese so it makes it easier for him to respond in a more detailed fashion!

Awesome, thanks for being our liaison!

 

[distracted]

Not hair related, but other developments coming from Riken Center:

http://www.riken.jp/en/research/rikenresearch/highlights/8012/

 

[paleocapa89]

BTW what do you think about this guys? It's in Japanese and google translate doesn't help much. The only thing I could get out of it is something something 10 years something...

http://nlab.itmedia.co.jp/nl/articles/1605/02/news102.html

 

[Solomon]

Quick question:

Is Tsuji's going to have transplant-like procedure or its like injection?

Thanks

 

[Pray The Bald Away]

Quick question:

Is Tsuji's going to have transplant-like procedure or its like injection?

Thanks

Injection.

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BTW what do you think about this guys? It's in Japanese and google translate doesn't help much. The only thing I could get out of it is something something 10 years something...

http://nlab.itmedia.co.jp/nl/articles/1605/02/news102.html

F*CK! Could this be an indication that Tsuji might take 10 years too? I hope Tsuji is ahead of these guys. Swoop is this the same procedure that Tsuji is developing?

 

[Torin]

Hello guys,

Been browsing this site for some time now. I too am very interested in Dr. Tsuji's work in hair regeneration. I think Tsuji lab's offers us the best possible chance of a de novo hair treatment in the coming decade.

Now obviously Tsuji's work is based around the creation of new hair follicles. The purpose of the treatment is not rejuvenating existing hairs that are thin/miniaturized. This seems to be what companies such as Replicel/Shiseido and Histogen are aiming to do.

So the question is, if most of your hair remains but it is thinned out/miniaturized, are you are maintaining it with propecia, would hair cloning of the kind being developed by Tsuji's lab be of little benefit for your scalp, except maybe in the temple recessions? I wonder what would happen if you injected Tsuji treatment stem cells into a frontal diffuse area for example.

Since there are a lot of guys at an NW2 level with diffuse thinning who might be looking at hair cloning as a future possible treatment, I think it is certainly worth asking if this treatment will even be relevant to such a candidate. It might be that hair cloning will work exclusively on slick bald areas, where existing follicles have been completely lost, thus leaving space for the treatment to fill those areas in with new hairs.

 

[distracted]

http://www.hairlosscure2020.com/ - Latest post is an interview with Tsuji.

 

[Swoop]

http://www.hairlosscure2020.com/ - Latest post is an interview with Tsuji.

Thanks, great that PDF is in depth! However this is a bit of a bummer or not? I don't see any mention of the hair follicle regeneration specifically?? He is mostly talking about that latest study regarding iPS cells..

However he does speak of searching for hair growth promoting agents in collobaration with adjuvant cosmetics!

 

[Pray The Bald Away]

Thanks, great that PDF is in depth! However this is a bit of a bummer or not? I don't see any mention of the hair follicle regeneration specifically?? He is mostly talking about that latest study regarding iPS cells..

However he does speak of seeking out hair growth promoting agents in collobaration with adjuvant cosmetics!

WTF. Does that mean he's throwing in the towel on hair-specific research? Or is he just misenterpreting what the admin was asking about?

 

[Dragonborn]

Thanks, great that PDF is in depth! However this is a bit of a bummer or not? I don't see any mention of the hair follicle regeneration specifically?? He is mostly talking about that latest study regarding iPS cells..

However he does speak of searching for hair growth promoting agents in collobaration with adjuvant cosmetics!

Well if I understood correctly the gist of it is that they want to start using their newly created skin for testing other drugs. And the skin for usage in humans would have to come from an in vitro generating system not an in vivo one (I think they grew the skin on mice and they want to grow it in a "Petri dish"). So this is basically what are they are trying to do nexT:

In future study, we would like to develop the in vitro culture system to generate the system but not in vivo transplantation model. Thus, we cannot answer the correct period to develop human clinical application. We would like to realize the application within 10 years.

However if I remember correctly Dr. Tsuji said the same timeline of 10 years in 2012. So we might have to wait for a while. Of course for all intents and purposes this is the cure no question about it. Unfortunately this will take some time to come to market.
Correct me if I said anything wrong here.
That said the bit about hair growth promoting agents in cosmetics sure sounds interesting.

 

[Pray The Bald Away]

I just realized that the studies that Desmond has been posting only apply to the dermal papilla stem cells, not the epithelial bulge stem cells. It's probably gonna take another several years to overcome that obstacle before he goes to trials.

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Thanks, great that PDF is in depth! However this is a bit of a bummer or not? I don't see any mention of the hair follicle regeneration specifically?? He is mostly talking about that latest study regarding iPS cells..

However he does speak of searching for hair growth promoting agents in collobaration with adjuvant cosmetics!

Swoop what was the date that Tsuji sent you the email about having issues expanding the epithelial bulge stem cells? I just found a study that was published on December 1st of last year that claims Wnt-3a aids in expanding them. That sounds like a solution to his other obstacle. Please get back to me on this.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430324/

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This is almost certainly why he is going to announce a partnership. Somebody else solved his final problems with expansion! I feel so bipolar right now.

 

[distracted]

This is almost certainly why he is going to announce a partnership. Somebody else solved his final problems with expansion! I feel so bipolar right now.

HAHA. Well Swoop said in someplace that he'd be emailing this week. I don't know if he chose to postpone it after we got a Tsuji update this week even though that FAQ document made no mention of hair loss...

 

[Pray The Bald Away]

HAHA. Well Swoop said in someplace that he'd be emailing this week. I don't know if he chose to postpone it after we got a Tsuji update this week even though that FAQ document made no mention of hair loss...

I read the whole study and it turns out that Wnt-3a was shown to maintain 8-10% of the bulge stem cell population for up to 10 days while being cultured. There's still some work to be done but a solution definitely doesn't seem too far away.

 

[distracted]

I read the whole study and it turns out that Wnt-3a was shown to maintain 8-10% of the bulge stem cell population for up to 10 days while being cultured. There's still some work to be done but a solution definitely doesn't seem too far away.

Honestly, I don't know crap about science. I know finance and that's about it. But maintain 8-10% for 10 days doesn't sound very good, does it?

 

[Pray The Bald Away]

Honestly, I don't know crap about science. I know finance and that's about it. But maintain 8-10% for 10 days doesn't sound very good, does it?

It's not ideal but the point is that they have somewhere to start instead of just throwing crap at the wall and seeing what sticks.

 

[Swoop]

Another interview with T. Tsuji;

http://itaintmagic.riken.jp/whats-up-with-us/organ-regeneration-lab/