sublime said:
docj077 said:
sublime said:
[quote="docj077":243f5]It's also important to remember that all polypeptide hormones in milk will be broken down by the digestive tract by the numerous peptidases that are in the stomach and secreted by the pancreas.
For this very reason, people can not take insulin, growth hormone, or any other polypeptide hormone orally. Steroid hormones are a different story.
So, oral intake of growth hormone, IGF-1, insulin, and all other polypeptide hormones (there are a lot of them) will be prevented. On the other hand, diamino acid compounds like thyroxine can easily be taken orally.
I wish people would remember such facts when they start freaking out about what is in their food.
I will see if I can find the canadian report that proves that untrue especially in the presence of casien. rbgh increases IGF-1 by 20-30% while pasteurization increases IGF-1 by 70%.
So, what the hell are you talking about? There is no possible way that peptide hormones will survive passage through the digestive tract whole. I don't care what any study says with regards to increased serum IGF-1 after a meal. It's impossible. Pure and simple. IGF-1 will increase so as to antagonize insulin.
If IGF-1 is increased in serum after eating or drinking dairy products, the cause is not dietary absorption, but dietary influence.
Seriously, you can't even dilute IGF-1 powder without it losing its potency. How would you expect it to be absorbed after traveling through a highly acidic environment filled with peptidases?
Pure and simple? I am guessing you still believe cigarettes are good for people. hhmmm. :wink:
"......provides both clear evidence that IGF-1 survives digestion (Xian et al, 1995) and an explanation for why the oral IGF-1 feeding studies looked at by JECFA in 1992 had ambiguous results, as is discussed below. Both the Monsanto-sponsored and the Elanco-sponsored studies previously considered by JECFA involved feeding free rIGF-1 by itself to rats. Neither used IGF-1 associated with its binding proteins (IGFBPs). IGFBPs are resistant to acidic conditions and may enable IGF-1 to survive digestion in the stomach (Corps and Brown, 1987; Donovan and Odle, 1994). Furthermore, in these two previous studies, the free IGF-1 was not mixed with other constituents of milk, such as casein, which more recent evidence indicates protect it from digestion."
"The demonstration that IGF-1 survives digestion through the protective effects of casein makes irrelevant the argument that human saliva contains IGF-1 at levels greater than the quantities that would be consumed in milk. As the IGF-1 produced by salivary glands is free IGF-1, without the protective effect of casein, it is unlikely to survive digestion.
Two earlier oral feeding studiesone sponsored by Monsanto and one by Elancoconcluded that IGF-1 does not survive digestion. Those studies are not definitive because rats were given free IGF-1, without casein or other protective proteins. Thus one would not expect the IGF-1 to survive digestion in these studies. Even so, a careful review of the Monsanto study suggested that some small amount of the IGF-1 administered in this study survived digestion and affected the rats' growth rate (Hansen, 1993)."